1. Leukemia By Mary Chen and Genesis Pimentel http://ny-image2.etsy.com/il_fullxfull.115519174.jpg

2. Website  http://whsleukemia.weebly.com http://whsleukemia.weebly.com  http://whsleukemia.weebly.com http://whsleukemia.weebly.com

3. What is leukemia?  Cancer of the blood  Begins in bone marrow  If healthy, makes white blood cells, red blood cells, and platelets  In a leukemia patient, unregulated growth of immature “leukemia” cells crowds out normal cells  Enters bloodstream  liver, spleen, lymph nodes  4 Major types:  Acute Myelogenous Leukemia (AML)  Acute Lymphoblastic Leukemia (ALL)  Chronic Myelogenous Leukemia (CML)  Chronic Lymphocytic Leukemia (CLL). http://upload.wikimedia.org/wikipedia/commons/6/6f/Leukemia_cells.png Abnormal leukemia cells

4. Types of Leukemia  Acute or chronic = how fast the cancer progresses  Acute immediate effects  Chronic gradual and may not show symptoms for years  Myelogenous or Lymphocytic/lymphoblastic depends on type of white blood cell it affects (lymphocytes or myelocytes)  Acute lymphoblastic leukemia: most common childhood cancer  Chronic lymphocytic leukemia: most common in adults, especially those older than 55; rare in children  Acute myelogenous leukemia: both children and adults  Chronic myelogenous leukemia: mainly in adults http://www.uchicagokidshospital.org/specialties/images/cms/uch1001089-1.jpg

5. Risk Factors  Genetics  Such as chromosomal abnormalities like down syndrome  Family history  Exposure to Dangerous Chemicals  formaldehyde and benzene  Exposure to High Levels of Radiation  Medical radiation like frequent X-rays  Nuclear fallout  Prior history of chemotherapy  Lifestyle factors  Smoking/drug abuse correlate with higher chances of developing leukemia (especially myelogenous leukemia) http://ocw.tufts.edu/data/graphics/genetics.jpghttp://ocw.tufts.edu/data/graphics/genetics.jpg, http://www.fotosearch.com/bthumb/SUE/SUE105/TOBW0151.jpg,http://www.fotosearch.com/bthumb/SUE/SUE105/TOBW0151.jpg http://www.scientificamerican.com/media/inline/D41DB314-E7F2-99DF-3D6ACEC215A9A006_1.jpg

6. Symptoms, Detection, & Diagnosis http://upload.wikimedia.org/wikipedia/commons/3/3a/Symptoms_of_leukemia.png  Common Symptoms  Detection & Diagnosis  physical exam  Swollen lymph nodes/spleen?  Paleness?  blood tests  bone marrow biopsy

7. Treatment  Depends on age, overall health, stage of cancer, type of cancer, and consideration of side effects  “remission” not “cure”  Chemotherapy: anti-cancer drugs to kill leukemia cells  Surgery: to remove enlarged spleen/cancerous areas  Radiation: high-dose X-rays to treat cancer cells that may stay after surgery  Bone Marrow Transplants: can rebuild a patient's supply of normal blood cells and boost their immune system  radiation or chemotherapy first to destroy the cells in the patient's bone marrow to make room for the donated cells  Biological Therapy: improve the body's natural defenses against cancer  Clinical Trials: studies to test new medicines and other possible treatments http://www.medicgo.com/wp-content/uploads/2010/08/Leukemia-Symptoms-Treatments1.jpghttp://www.medicgo.com/wp-content/uploads/2010/08/Leukemia-Symptoms-Treatments1.jpg, http://blog.oregonlive.com/hg_impact/2009/04/Marissa_Huddleston_and_brother_Kellen.jpghttp://blog.oregonlive.com/hg_impact/2009/04/Marissa_Huddleston_and_brother_Kellen.jpg There are side effects for certain treatments. Chemotherapy causes temporary hair loss.

8. 5-Year Survival Rate  National Cancer Institute Surveillance Epidemiology and End Results Review 2010 Estimate  43,050 new cases will be diagnosed in US; 21,840 will die  Overall 5-year relative survival from 17 different geographic areas was 54.1%  Breakdown by race and gender  54.6% for white males, 54.2% for white females  46.8% for black males, 46.2% for black females.  In US, estimated middle age of death for leukemia is 74 years http://en.wikipedia.org/wiki/File:Leukaemia_world_map_-_Death_-_WHO2004.svg

9. Interesting Facts  History  Greeks first recognized the disease in the 5th century  "leukemia" comes from Greek "leukos" + "hemia" = white blood  John Hughes Benett made the first diagnosis in 1845, Edinburgh  The disease  affects more men than women but men have a slightly higher survival rate  chronic is more common among older people while acute is mainly pediatric http://www.unitedproject.org/images/ribbon_normal/22-orange.jpg

10. Famous People With Leukemia  Ed Bradley Marie Curie Mary Travers Bill Walsh http://www.aolcdn.com/channels/0f/01/455371ba-002b2-04ec9-400cb8e1http://www.aolcdn.com/channels/0f/01/455371ba-002b2-04ec9-400cb8e1, https://thescienceclassroom.wikispaces.com/file/view/Marie_curie_pic.jpg/66535110/Marie_curie_pic.jpg,https://thescienceclassroom.wikispaces.com/file/view/Marie_curie_pic.jpg/66535110/Marie_curie_pic.jpg http://www.chapelhillmemories.com/uploads/Image/P%20MaryJPG%20Medium%20Web%20view.jpg

11. Works Cited  Davis, Bets. "Leukemia - Symptoms, Types, Causes, Diagnoisis and Treatment Options for Leukemia." WebMD. Healthwise, 26 Nov. 2008. Web. 12 Oct. 2010..http://www.webmd.com/cancer/tc/leukemia-topic- overview  "Facts About Leukemia." Cancer Prevention. 2010. Web. 13 Oct. 2010..http://www.your-cancer-prevention- guide.com/facts-about-leukemia.html  "Famous People With Leukemia." HistoryKing. History King, 2010. Web. 16 Oct. 2010..  Feist, Patty. "Signs of Childhood Cancer." Pediatric Oncology Resource Center. Association of Cancer Online Resources, July 2005. Web. 12 Oct. 2010..http://www.acor.org/ped-onc/diseases/SOCC.html>.  Leukemia." MayoClinic. Mayo Foundation for Medical Education and Research, 3 Apr. 2010. Web. 13 Oct. 2010..http://www.mayoclinic.com/health/leukemia/DS00351  "Leukemia Home Page." National Cancer Institute. National Cancer Institute, 2010. Web. 11 Oct. 2010..http://www.cancer.gov/cancertopics/types/leukemia  "Leukemia Risk Factors." Oncology Channel. 04 Dec. 2007. Web. 12 Oct. 2010..http://www.oncologychannel.com/leukemias/risk-factors.shtml  Myrrh, Hector. "Leukemia 101." About.com. The New York Times Company, 8 May 2010. Web. 12 Oct. 2010..http://leukemia.about.com/od/whatisleukemia/a/leukemia101.htm