1. Hemophilia A  A hereditary bleeding disorder caused by a lack of the blood clotting factor VIII  Located on the X chromosomes  Females have two X chromosomes the become carriers  Males only have 1 they receive the defect.  Symptoms are mainly internal bleeding, external bleeding.  A hereditary bleeding disorder caused by a lack of the blood clotting factor VIII  Located on the X chromosomes  Females have two X chromosomes the become carriers  Males only have 1 they receive the defect.  Symptoms are mainly internal bleeding, external bleeding.

2. Impact  People live normal lives for the most part  They see regular care from a hematologist  There are also support groups  In some cases, one will bleed to death if injury is major  People live normal lives for the most part  They see regular care from a hematologist  There are also support groups  In some cases, one will bleed to death if injury is major

3. Cellular cause of Hemophilia  The defect will be located on the X chromosome  The factor VIII gets broken on the X chromosome  The defect will be located on the X chromosome  The factor VIII gets broken on the X chromosome

4. Treatment  Only three main treatments  1) BE CAREFUL!  2) replacing the missing clotting factor  3) DDAVP or desmopressin  Only three main treatments  1) BE CAREFUL!  2) replacing the missing clotting factor  3) DDAVP or desmopressin