2. (3,4,methylenedioxymethamphetamine) Ecstasy
A designer amphetamine that has become one of the most widely abused drugs in the adolescents
A blending of sympathomimetic amphetamine stimulation with the hallucinogenic effects of mescaline
The drug is popular at “rave “ parties and at dance clubs.
Following ingestion, the onset of action is 30 – to 90 minutes, plateau effects are achieved in 2- 3 hours
The drug is abused because it induces extreme euphoria, increased energy, feeling of belongings, heightened sensations, empathy, music appreciation

3. Toxic effects & Major complications
Bruxism
Trismus
Short-term memory loss
Confusion
Headches
Vertigo
Ataxia
Vomiting
Depression&psychological addiction
Profound hyperthermia
Hypertension
Seizures
Dehydration
Hyponatremi
Hepatic and renal failure
Rhabdomyolysis
MI & ICH

4. Psychological Euphoria Closeness to others love drug
Serotonergic properties
Shimmering visual effects

5. Differential Diagnosis
Amphetamines
LSD
Phencyclidine abuse

6. Management Supportive care, airway management, rapid cooling
Liberal doses of benzodiazepines for tachycardia,hypertension, and agitation
Activated charcoal
Toxicology urine screens that are marketed to detect amphetamines can be negative after ecstacy and desighner amphetamine use
Fluid

7. Management Consultation with a local or regional poison center
Observation for4 to 6 hours
Because of % repeat ingestion, families must be received a kind of instuction about poison prevention
Admission to the hospital(slow release substances and or ingestion of significant amounts of drug
A conservative approach for toxins that can cause potential mortality in small doses (camphor, benzocaine, lomotil, chloroquin, methyl salicylate
All patients with intentional overdoses should undergo psychiatric assessment