1. Merve ÖZDEMİR KIDNEY TRANSPLANT

2. Content  What causes kidney failure?  What is a kidney transplant?  Are there different kinds of kidney transplants?  During a transplant  Animation  What is rejection?  What are the side effects of the anti-rejection medications?

3. What causes kidney failure? Kidney failure can occur from an acute situation or from chronic problems. In acute renal failure, kidney function is lost rapidly. The list of causes is often categorized based on where the injury has occurred. Prerenal causes (pre=before + renal=kidney) causes are due to decreased blood supply to the kidney. Examples of prerenal causes of kidney failure are: (low blood volume) due to blood loss; Dehydration from loss of body fluid (for example, sweating); poor intake of fluids; medication

4. What is a kidney transplant? A kidney transplant is an operation in which a person whose own kidneys have failed receives a new kidney to take over the work of cleaning the blood.

5. Are there different kinds of kidney transplants? There are two types of kidney transplants: those that come from living donors and those that come from unrelated donors who have died (non-living donors). A living donor may be someone in your immediate or extended family or your spouse or close friend, and in some cases a stranger who wished to donate a kidney to anyone in need of a transplant.

6. During a transplant; The surgeon places the new kidney in your lower abdomen and connects the artery and vein of the new kidney to your artery and vein. Often, the new kidney will start making urine as soon as your blood starts flowing through it. But sometimes it takes a few weeks to start working.

7. Here there is an animation: http://www.kidneypatientguide.org.uk/site/TRAa nim.php http://www.kidneypatientguide.org.uk/site/TRAa nim.php

8. Many transplanted kidneys come from donors who have died. Some come from a living family member. The wait for a new kidney can be long. People who have transplants must take drugs to keep their body from rejecting the new kidney for the rest of their lives.

10. What is rejection? The most important complication that may occur after transplant is rejection of the kidney. The body's immune system guards against attack by all foreign matter, such as bacteria. This defense system may recognize tissue transplanted from someone else as "foreign" and act to combat this "foreign invader."

11. People will need to take medications every day to prevent rejection of your new kidney. Most patients need to take three types. The major one is usually cyclosporine or tacrolimus or sirolimus

12. What are the side effects of the anti- rejection medications? Anti-rejection medications have a large number of possible side effects because the body's immune defenses are suppressed. Fortunately, these side effects usually are manageable for most patients. If side effects do occur, changing the dose or type of the medications will usually take care of them.

13. Some of the most common side effects include high blood pressure, weight gain and a susceptibility to infections and tumors. You may also require additional medications to maintain blood pressure and prevent ulcers and infections.

14. SOURCES: http://www.kidneypatientguide.org.uk/site/TRAa nim.php http://www.kidneypatientguide.org.uk/site/TRAa nim.php http://www.nlm.nih.gov/medlineplus/kidneytrans plantation.html http://www.nlm.nih.gov/medlineplus/kidneytrans plantation.html http://www.kidney.org/atoz/content/kidneytransn ewlease.cfm http://www.kidney.org/atoz/content/kidneytransn ewlease.cfm

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