1. From Discoveries to Cures SOM Graduate Education Office Paul MacDonald Martin Snider Robert Petersen Monica Montano George Dubyak Diana Ramirez-Bergeron Joseph Williams Deborah Noureddine Malana Bey Dan Korgan

2. From Discoveries to Cures Seeds of Discovery The Ph.D. White Lab Coat Ceremony 76 students entering 11 different programs 57 % female, 43 % male 11 different countries (33 %) 36 % from Ohio, 11 % from CWRU

3. From Discoveries to Cures Guiding Principles for Graduate Education preparing students for success as future leaders in the rapidly changing biomedical research environment of the 21 st century. an interdisciplinary, concept-driven curriculum rather than content-driven approaches that stimulate active interchange of ideas among students and faculty fosters collaboration among students and faculty…safe learning environments students and faculty as colleagues independent study, self-directed learning, and life-long learning skills a professional skill set beyond the academic research profession

4. From Discoveries to Cures Guiding Principles for Graduate Education preparing students for success as future leaders in the rapidly changing biomedical research environment of the 21 st century. Students develop a set of core research competencies: Broad foundational knowledge of discipline, depth of knowledge in their field Interdisciplinary knowledge of experimental methods Think and communicate clearly, oral and written Plan and execute experiments Read, critically evaluate, and integrate scientific literature Ability to think creatively and acquire creative problem solving skills

5. From Discoveries to Cures Biochemistry Tracks: RNA Biology Structural Biology & Biophysics Bioethics Biomedical Engineering Cell Biology Epidemiology and Biostatistics Genetics Tracks: Developmental Biology Molecular Biology and Microbiology Molecular Medicine Molecular Virology Neurosciences Tracks: Developmental Biology Nutrition Pathology Tracks: Cancer Biology Exp. Pathology Immunology Mol. Cell. Basis of Disease Pharmacology Tracks:Cancer Therapeutics, Molecular Pharmacology, Membrane Structural Biology, Translational Therapeutics Physiology and Biophysics Systems Biology & Bioinformatics Ph.D. Graduate Programs at CWRU

6. From Discoveries to Cures 1.Biomedical Sciences Training Program – BSTP 2.Medical Scientist Training Program – MSTP Dual-degree – M.D./Ph.D. 3.Direct Admission to programs SOM Ph.D. Entry Routes

7. From Discoveries to Cures Students enter together, then earn a PhD in one program First semester: cell & molecular biology Lab rotations with prospective advisors PhD: Biomedical Sciences Training Program

8. From Discoveries to Cures Over 200 faculty advisors Smaller labs with individual attention PhD: Biomedical Sciences Training Program

9. First and Second Years: Initial Recruit coursework, grades rotations selection of thesis advisor At the end of the second year: Candidacy Exam = Qualifier Third Year, plus: Doctoral Candidate publish journal papers fellowships go to conferences thesis and oral defense career goal-setting End of Fifth Year: Graduate and Go On Typical Progress in Biomedical PhD Program From Discoveries to Cures

10. CWRU MSTP NIH funded Medical Scientist Training Program, 1956 2 years medical school + 4 years PhD + 2 years clerkships Accept about a dozen students/year

11. From Discoveries to Cures MS in Anesthesia MS Applied Anatomy MS in Biochemical Research MS in Biochemistry JD/MS in Biochemistry MD/MS Biomedical Investigation MA in Bioethics MD/MA in Bioethics MS in Engineering MS in Clinical Research MS Degree in Translation Bioinformatics MS Environmental Health Science MS in Biostatistics Master of Public Health (MPH) MS Genetic Counseling MS Public Health Nutrition MS Coordinated Dietetic MS in Pathology MS in Pharmacology MS in Medical Physiology Master Programs at CWRU SOM

12. From Discoveries to Cures SOM Graduate Students, Steady State 2013 n 348 36 179 169 272 76 Total URM Female Male Citizen Foreign % 100 10.3 51.4 48.6 78.2 21.8 n 535 58 309 226 466 69 % 100 10.8 57.8 42.2 87.1 12.9 SOM PhD studentsSOM Masters students

13. From Discoveries to Cures Ph.D. Time to Degree and Publications ave TTD ave # pubs/program # pubs/grad Ave primary pubs/program primary pubs/grad 5.7 103.1 3.8 47.9 1.7 5.5 109.4 3.1 54.7 1.5 2002-20072008-2013

14. From Discoveries to Cures ~ 7 mil in annual total costs, 70 predoc slots, 33 postdoc slots Training in Geographic Medicine & Infectious Diseases Immunology Training Program- Predoctoral Training Program in Musculoskeletal Research Training in Investigative & Molecular DermatologyCancer Biology Training Grant Metabolism Training Grant CWRU Nephrology Training Grant Cardiovascular Research Training Program (CRTP) Predoctoral Training in Neurosciences Molecular Medicine Training Program Visual Sciences Training Program CWRU Institutional Training Grants Integrated Engineering and Rehabilitation Training Interdisciplinary Biomedical Imaging Training Program Case Urology Translational Research Training Program (CUTRTP) Combined Training Program in Digestive Disease Sciences

15. From Discoveries to Cures 8-10 wk lab research Science, career seminars poster session $3,500 stipend Travel, housing About 80 students Deadline Feb1 Summer Research Internships

16. From Discoveries to Cures Postbaccalaureate Research Education Program NIH funded program to prepare for graduate school One year in dynamic research lab Math or science courses GRE workshop and practice sessions