1. Tuberculosis in the UK 2013 report
Tables and figures slide-set

2. 1. Tuberculosis case reports, UK, 2000-2012
Tuberculosis in the UK: 2013 report

3. Figure 1.1: Tuberculosis case reports and rates, UK, 2000-2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
3 Tuberculosis in the UK: 2013 report

4. Figure 1.2: Tuberculosis case reports and rates by country, UK, 2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
4 Tuberculosis in the UK: 2013 report

5. Figure 1. 3. Three-year average tuberculosis case rates by local area
Figure 1.3. Three-year average tuberculosis case rates by local area*, UK,
*England – Local authorities, Wales and Scotland – Health Boards, NI – data not available
London
© Crown copyright and database rights 2013 Ordnance Survey
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
5 Tuberculosis in the UK: 2013 report

6. Figure 1. 4: Tuberculosis case reports and rates by region
Figure 1.4: Tuberculosis case reports and rates by region*, England, 2012
* HPA region
CI – 95% confidence intervals
Source: Enhanced Tuberculosis Surveillance (ETS), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
6 Tuberculosis in the UK: 2013 report

7. Figure 1.5: Tuberculosis case reports and rates by PHE Centre, England, 2012
CI - confidence intervals
Source: Enhanced Tuberculosis Surveillance (ETS), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
7 Tuberculosis in the UK: 2013 report

8. Figure 1.6: Tuberculosis case reports by place of birth and country, UK, 2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
8 Tuberculosis in the UK: 2013 report

9. Figure 1.7: Tuberculosis case reports by place of birth and PHE Centre, England, 2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
9 Tuberculosis in the UK: 2013 report

10. Figure 1.8: Non UK-born tuberculosis case reports by time since entry to the UK to tuberculosis diagnosis, UK, 2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
10 Tuberculosis in the UK: 2013 report

11. Table 1.1: Most frequent countries of birth for non UK-born tuberculosis cases, UK, 2012
* Where country of birth was known; **Years
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
11 Tuberculosis in the UK: 2013 report

12. Figure 1.9: Tuberculosis case reports and rates by ethnic group and place of birth, England, Wales and Northern Ireland, 2012
Source: Enhanced Tuberculosis Surveillance (ETS), Rates by place of birth calculated using Labour Force Survey population estimates.
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
12 Tuberculosis in the UK: 2013 report

13. Figure 1.10: Tuberculosis case reports and rates by age group and place of birth, UK, 2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
13 Tuberculosis in the UK: 2013 report

14. Figure 1.11: Tuberculosis case reports and rates by age group and sex, UK, 2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
14 Tuberculosis in the UK: 2013 report

15. Figure 1.12: Tuberculosis case reports and rates by place of birth, UK, 2000-2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
15 Tuberculosis in the UK: 2013 report

16. Figure 1.13: Proportion of tuberculosis case reports by site of disease (pulmonary/extra-pulmonary), UK,
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
16 Tuberculosis in the UK: 2013 report

17. Table 1.2: Tuberculosis case reports by site of disease, UK, 2012
*With or without disease at another site **Percentage of cases with known sites of disease (8751)
±For Scotland cases, this includes both cryptic and miliary site
CNS - Central Nervous System
  Total percentage exceeds 100% due to infections at more than one site
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
17 Tuberculosis in the UK: 2013 report

18. Figure 1.14: Child to adult ratio in notifications rate, UK, 2000-2012
The child-to-adult ratio is the ratio of the case notification rate in children under 15 years of age, to that in adults. A declining trend in the ratio suggests a decrease in ongoing transmission (European Centre for Disease Prevention and Control).
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
18 Tuberculosis in the UK: 2013 report

19. 2. Microscopy, culture confirmation, speciation and drug susceptibility
Tuberculosis in the UK: 2013 report

20. Figure 2.1: Proportion of cases with first line drug resistance or MDR-TB, UK, 2000-2012
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

21. Table 2.1: Number and proportion of tuberculosis cases with drug resistance by age group, UK, 2012
*First line drugs - isoniazid, rifampicin, ethambutol and pyrazinamide**First line drugs – isoniazid, rifampicin, ethambutol and pyrazinamide
**Culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

22. Table 2.2: Proportion of tuberculosis cases with drug resistance by previous history of tuberculosis, UK, 2012*
* Cases with unknown previous history of tuberculosis are excluded
** First line drugs - isoniazid, rifampicin, ethambutol and pyrazinamide
$ Culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

23. Table 2.3: Number and proportion of tuberculosis cases with drug resistance by place of birth, UK, 2012*
* Cases with unknown previous history of tuberculosis are excluded
** First line drugs - isoniazid, rifampicin, ethambutol and pyrazinamide
$ Culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

24. Figure 2.2: Proportion of tuberculosis cases isoniazid and multi-drug resistance by place of birth and previous history of tuberculosis, UK, 2012*
* Cases with unknown place of birth and unknown previous history of TB are not included
Culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

25. Figure 2.3: Proportion* of multi-drug resistance cases from Eastern Europe, South Asia and Sub-Saharan Africa with additional resistance, UK, 2012
*Proportion were calculated out of those who were tested
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

26. 3. Strain typing,
Tuberculosis in the UK: 2013 report

27. Table 3.1: Number and proportion of culture confirmed cases typed or with 23 loci typed by year and country
* Culture confirmed cases with a MIRU-VNTR profile with at least 23 complete loci
** Clustered cases are clustered within geographical area
$ Calculated using the n-1 method (number of cases in a cluster-number of clusters/number of cases with a strain type)
‡ The number of clusters in England, Wales and Northern Ireland is higher than the sum of all clusters in the three countries because it includes clusters that span more than one country
§ The number of clusters in England is higher than the sum of all PHEC clusters because it includes clusters that span more than PHEC
# The number of culture confirmed cases in Northern Ireland reported here is less than the 157 culture confirmed cases known about locally
Source: Enhanced Tuberculosis Surveillance (ETS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
27 Tuberculosis in the UK: 2013 report

28. Table 3.2: Number of tuberculosis cases and proportion of clustering stratified by place of birth,
* Culture confirmed cases with a MIRU-VNTR profile with at least 23 complete loci
** Calculated using the n-1 method (number of cases in a cluster-number of clusters/number of cases with a strain type)
$ The number of cases in England, Wales and Northern Ireland is higher than the sum UK-born and non UK-born as 583 cases have unknown UK-born information
‡ Number of clusters with at least one UK-born person in the cluster
§ Number of clusters with at least one non UK-born person in the cluster
Source: Enhanced Tuberculosis Surveillance (ETS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
28 Tuberculosis in the UK: 2013 report

29. 4. TB treatment outcomes, UK, 2001-2011
Tuberculosis in the UK: 2013 report

30. Table 4.1: Treatment outcome at 12 months for tuberculosis cases, UK, 2011*
* Excludes MDR-TB and RMP-resistant TB cases. Not evaluated includes missing, unknown and transferred out
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

31. Figure 4.1: Trends in tuberculosis treatment outcomes at 12 months post start of treatment, UK*
*Cases who developed MDR or rifampicin resistance while on treatment were not available for years prior to 2010 and will remain in the 12 month treatment outcome cohort for these years. These data were also not available for Scotland.
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

32. Figure 4.2: Proportion of cases completing treatment by Country and PHE Centre, UK, 2011
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

33. Table 4.1: Relationship between tuberculosis diagnosis and cause of death at 12 months, UK, 2011
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report

34. Figure 4.3: Treatment outcomes at 12 months for tuberculosis cases by place of birth, UK, 2011
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Annual report on tuberculosis surveillance in the UK 2013

35. Figure 4.4: Treatment outcomes at 12 months for tuberculosis cases with at least one social risk factor, UK, 2011
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Annual report on tuberculosis surveillance in the UK 2013

36. Figure 4.5: Treatment outcomes at 12 months for tuberculosis cases with previous history of TB, UK, 2011
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Annual report on tuberculosis surveillance in the UK 2013

37. Table 4.3: Treatment outcome at 24 months for MDR and rifampicin resistant tuberculosis cases, UK, 2010
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Annual report on tuberculosis surveillance in the UK 2013