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The Cardiovascular System

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1 The Cardiovascular System
26 The Cardiovascular System

2 Learning Outcomes (cont.)
26.1 Describe the structures of the heart and the function of each. 26.2 Explain the cardiac cycle, including the cardiac conduction system. 26.3 Compare pulmonary and systemic circulation.

3 Learning Outcomes (cont.)
26.4 Differentiate among the different types of blood vessels and their functions. 26.5 Explain blood pressure and tell how it is controlled. 26.6 Describe the causes, signs and symptoms, and treatments of various diseases and disorders of the cardiovascular system.

4 Introduction The cardiovascular system Heart Blood vessels
Sends blood to Lungs for oxygen Digestive system for nutrients Also circulates waste products for removal Learning Outcomes: Describe the structures of the heart and the function of each. This system also circulates waste products to certain organ systems so these wastes can be removed from the blood.

5 The Heart Cone-shaped organ Size of a loose fist
Slightly left of the midline Bordered by Lungs Sternum and vertebral column Diaphragm Learning Outcomes: Describe the structures of the heart and the function of each. Located in the mediastinum and extends from the level of the second rib to about the level of the sixth rib.

6 Cardiac Membranes Pericardium Pericardial sac
Covers the heart and large blood vessels Fibrous outer layer Visceral pericardium ~ epicardium Parietal pericardium Pericardial sac Pericardial cavity – pericardial fluid Learning Outcomes: Describe the structures of the heart and the function of each. Pericardium Consists of an outer fibrous layer that covers two inner layers. The visceral pericardium [ epicardium]– the innermost layer It is also the outer layer of the heart wall. The parietal pericardium – the layer on top of the visceral pericardium Pericardial sac – formed by fibrous pericardium and the parietal pericardium The pericardial cavity the space between the parietal pericardium and visceral pericardium. Contains pericardial fluid that reduces friction between the membranes when the heart contracts.   Cardiac Membranes

7 Cardiac Membranes (cont.)
Learning Outcomes: Describe the structures of the heart and the function of each. Back

8 The Heart Wall Epicardium Myocardium Endocardium Thin, smooth layer
Contains part of electrical conduction system Learning Outcomes: Describe the structures of the heart and the function of each. Epicardium The visceral pericardium Contains fat – cushions the heart Myocardium Middle layer and thickest layer of the wall Primarily of cardiac muscle Endocardium – innermost layer stretches as the heart pumps blood. Heart Wall

9 Heart Chambers and Valves
Four chambers Two atria Upper chambers Interatrial septum Atrioventricular septum separates the atria from the ventricles Two ventricles Lower chambers Interventricular septum Learning Outcomes: Describe the structures of the heart and the function of each. The heart contains four hollow chambers. Atria Thin walled Receive blood returning to the heart from the lungs and the body Interartrial septum – walled membrane separating atria Ventricles Interventricular septum – separates the ventricles Function to pump blood into the arteries, which send the blood to the lungs and the body. The atrioventricular septum is the wall that separates the atria from the ventricles. Click for View of Heart

10 Heart Chambers and Valves (cont.)
Valves between atria and ventricles Tricuspid ~ three cusps Bicuspid ~ two cusps Valves between ventricles and arteries Pulmonary semilunar Aortic semilunar Learning Outcomes: Describe the structures of the heart and the function of each. The four valves keep blood flowing in one direction. Tricuspid Valve [right atrioventricular (AV) valve] Prevents blood from flowing back into the right atrium when the right ventricle contracts. Chordae tendineae – cord-like structures that anchor the cusps of the valve to papillary muscles that contract close the valve. Bicuspid valve [mitral valve or left AV valve] Prevents blood from flowing back into the left atrium when the left ventricle contracts. Also has chordae tendineae. Pulmonary semilunar valve Between the right ventricle and the trunk of the pulmonary arteries Prevents blood from flowing back into the right ventricle. Semilunar – cusps are shaped like a half moon Aortic semilunar valve Situated between the left ventricle and the aorta Prevents blood from flowing back into the left ventricle Also semilunar Click for View of Heart

11 The Heart Labeled Learning Outcomes: Describe the structures of the heart and the function of each. Back

12 Good Job! Apply Your Knowledge ANSWER: Match the following:
__ Tricuspid valve A. Outermost layer of the heart wall __ Bicuspid valve B. Covering of the heart and aorta __ Intraventricular C. Between the right atrium and the right septum ventricle Ventricles D. Pump blood into the arteries Pericardium E. Primarily cardiac muscle Epicardium F. Between the left atrium and the left ventricle Myocardium G. Inner most layer of the heart wall Endocardium H. Separates the ventricles C F H D Learning Outcomes: Describe the structures of the heart and the function of each. B A E G Good Job!

13 Cardiac Cycle One heart beat = one cardiac cycle
Right atrium contracts  tricuspid valve opens  blood flows into right ventricle Left atrium contracts  bicuspid valve closes  blood flows into left ventricle Learning Outcome: 26.2 Explain the cardiac cycle, including the cardiac conduction system. One cardiac cycle consists of one complete cardiac contraction and one complete cardiac relaxation.

14 Cardiac Cycle (cont.) Right ventricle contracts  tricuspid valve
closes  pulmonary semilunar valve opens  blood is pushed into pulmonary artery Left ventricle contacts  bicuspid valve closes  aortic semilunar valve opens  blood is pushed into aorta Learning Outcome: 26.2 Explain the cardiac cycle, including the cardiac conduction system. . Refer to CONNECT to see an animation on Cardiac Cycle

15 Cardiac Cycle (cont.) Influenced by Exercise Parasympathetic nerves
Cardiac control center Body temperature Potassium ions Calcium ions Learning Outcome: 26.2 Explain the cardiac cycle, including the cardiac conduction system. Exercise – increases the heart rate because skeletal muscles need more oxygen. Parasympathetic nerves – (vagus nerve) generally keep the heart rate relatively low. Sympathetic nerves – increase the heart rate during times of stress. Cardiac control center – located in the medulla oblongata. When blood pressure rises, impulses are sent to decrease the heart rate. When blood pressure falls, impulses are sent to increase the heart rate. Body temperature – an increase in body temperature usually increases the heart rate. Potassium ions A low concentrations of potassium ions in the blood decrease the heart rate A high concentration causes an arrhythmia. Calcium ions Low concentrations of calcium ions in the blood depress heart actions High concentrations cause heart contractions called titanic contractions –longer than normal contractions

16 Heart Sounds Lubb Dubb Murmur – abnormal heart sound First sound
Occurs when ventricles contract and the tricuspid and bicuspid valves snap shut Dubb Second sound Occurs when atria contract and the pulmonary and aortic valves snap shut Murmur – abnormal heart sound Click for Heart Sounds Learning Outcome: 26.2 Explain the cardiac cycle, including the cardiac conduction system. During one cardiac cycle, you can hear two heart sounds – lubb and dubb. If a valve is damaged, it will not close completely and blood leaks back into the atria or ventricles. This produces an abnormal heart sound called a murmur.

17 Cardiac Conduction System
Sinoatrial node Right atrium Natural pacemaker Sends impulse to AV node Atrioventricular node Between atria and just above ventricles Sends impulse to the bundle of His Learning Outcome: 26.2 Explain the cardiac cycle, including the cardiac conduction system. The cardiac conduction system sends electrical impulses through the heart stimulating the heart muscle to contract. Sinoatrial node (SA node) Natural pacemaker - it generates the heart’s rhythmic contractions. Generates an impulse that flows to the atrioventricular node.  Atrioventricular node (AV node) – after the impulse reaches the AV node, the atria contract Click for Conduction System

18 Cardiac Conduction System (cont.)
Bundle of His Between ventricles Right and left bundle branches Sends impulse to Purkinje fibers Purkinje fibers Lateral walls of ventricles Ventricles contract Learning Outcome: 26.2 Explain the cardiac cycle, including the cardiac conduction system. Bundle of His [atrioventricular or AV bundle] – splits into two branches before sending the electrical impulse to the Purkinje fibers. Purkinje fibers – after the impulse flows through the Purkinje fibers, the ventricles contract and the SA node starts the flow of a new impulse. An electrocardiogram (ECG or EKG) is performed to determine if the cardiac conduction system is working properly. Click for Conduction System

19 Cardiac Conduction System (cont.)
Learning Outcome: 26.2 Explain the cardiac cycle, including the cardiac conduction system. Back

20 Smashing! Apply Your Knowledge ANSWER: Match the following:
__ Right ventricle A. Two branches; sends impulse to Purkinje fibers __ Left ventricle B. Located in the medulla oblongata __ Cardiac control C. Contraction pushes blood into the lungs center __ SA node D. In the lateral walls of ventricles __ Bundle of His E. Natural pacemaker __ Purkinje fibers F. Contraction sent blood to the aorta C F B E Learning Outcome: 26.2 Explain the cardiac cycle, including the cardiac conduction system. A D Smashing!

21 Circulation Pulmonary circulation Systemic Circulation
In the body, the blood gives oxygen to cells and picks up carbon dioxide. Veins of the body pick up the oxygen-poor blood and empty it into the venae cavae, and the whole system starts all over again with pulmonary circulation. Circulation Pulmonary circulation Oxygenates blood Removes carbon dioxide Systemic Circulation Delivers oxygen and nutrients Removes carbon dioxide and waste products Learning Outcome: Compare pulmonary and systemic circulation. Blood flows through the body through two main circuits. Pulmonary circulation The route that blood takes from the heart to the lungs and back to the heart again. In the lungs, blood picks up oxygen and gets rid of carbon dioxide. Systemic circulation The route blood takes from the heart through the body and back to the heart. The function of this circuit is to deliver oxygen and nutrients to body cells and picks up carbon dioxide and waste products.

22 Pulmonary Circulation Pulmonary Semilunar Valve Aortic Semilunar Valve
Circulation (cont.) Pulmonary Circulation Right Atrium Tricuspid Valve Right Ventricle Pulmonary Semilunar Valve Body Lungs Learning Outcome: Compare pulmonary and systemic circulation. Pulmonary Circulation Deoxygenated blood that is rich in carbon dioxide enters the right atrium of the heart via the inferior and superior venae cavae. Blood leaves the ventricles via the pulmonary semilunar valve into the pulmonary trunk which branches into the pulmonary arteries that carry deoxygenated blood to the lungs. Systemic Circulation Oxygenated blood from the lungs flows through the left atrium and bicuspid valve into the left ventricle. When the left ventricle contracts, blood is pushed through the aortic semilunar valve into the aorta. Veins of the body pick up the oxygen-poor blood and empty it into the venae cavae, and the whole system starts all over again with pulmonary circulation. Aortic Semilunar Valve Left Ventricle Bicuspid Valve Left Atrium Systemic Circulation

23 Apply Your Knowledge Correct!
What are the functions of the pulmonary and systemic circulations? ANSWER: The pulmonary circulation functions to oxygenate the blood and remove carbon dioxide. The systemic circulation delivers oxygen and nutrients to and removes carbon dioxide and waste products from the body’s cells. Learning Outcome: Compare pulmonary and systemic circulation. Correct!

24 Blood Vessels Form a closed pathway that carries blood from the heart to cells and back to the heart Learning Outcome: Differentiate among the different types of blood vessels and their functions.

25 Arteries and Arterioles
Thick muscular wall Carry blood under high pressure Arterioles Coronary arteries Supply heart muscle Coronary sinus Pulmonary arteries Heart to lungs Deoxygenated blood Aorta Learning Outcome: Differentiate among the different types of blood vessels and their functions. Arteries The strongest blood vessels Their smooth muscle is thicker than that of other types of blood vessels. They carry blood away from the heart and are under high pressure. The muscular wall of an artery constricts to increase blood pressure or dilates to decrease blood pressure. Arterioles – small branches of arteries. Coronary Arteries Supply blood to the tissues of the heart. Branches down to very small blood vessels called capillaries. Blood leaving the capillaries in the heart enters the cardiac veins. Cardiac veins eventually deliver the oxygen-poor blood to the coronary sinus which empties the blood into the right atrium. Pulmonary arteries carry oxygen-poor blood from the heart to the lungs. The aorta comes directly off the left ventricle and has many branches that carry blood to the body. Other arteries are paired – right and left Refer to Table 26-1 Major Arteries of the Body.

26 Veins and Venules Veins Deoxygenated blood
Skeletal muscle contractions move blood Valves prevent back flow Sympathetic nervous system effect Learning Outcome: Differentiate among the different types of blood vessels and their functions. Veins Carry blood toward the heart. Blood is under no pressure in the veins and does not move very easily. The movement of blood through veins requires skeletal muscle contractions and valves to prevent blood from flowing backward. The sympathetic nervous system causes vein walls to constrict forcing blood through the veins if blood pressure gets abnormally low in the arteries.

27 Veins and Venules Venules Pulmonary veins – oxygenated blood
Superior and inferior vena cava Hepatic portal system Learning Outcome: Differentiate among the different types of blood vessels and their functions. Venules Very small blood vessels formed when capillaries merge. Venules merge to make veins, the largest of which are the superior and inferior venae cavae. Most veins in the body carry oxygen-poor blood, except the pulmonary veins, which carry oxygenated blood from the lungs to the heart. Hepatic portal system Collection of veins that carry blood to the liver. The liver processes nutrients in the blood and returns it to general circulation through the hepatic veins. Refer to Table 26-2 Major Veins of the Body.

28 Capillaries Branches of arterioles Connect arterioles to venules
Exchange vessels Oxygen and nutrients Carbon dioxide and waste products Water Learning Outcome: Differentiate among the different types of blood vessels and their functions. Capillaries The smallest type of blood vessel They have very thin walls about one cell layer thick allowing substances to pass into and out of capillaries. Exchange vessels – capillaries are the only blood vessels that allow substances to move in and out of the blood Precapillary sphincters – control the amount of blood that flows into them The substances move through the capillary wall through diffusion, filtration, and osmosis. Oxygen and nutrients diffuse out of the capillary and into body cells. Carbon dioxide and waste products diffuse out of the cells into the capillary. Water is forced through the capillary wall via filtration into a body cell. By the time blood leaves a capillary, it has a high solid concentration and a low water concentration so water back into the capillary by osmosis.

29 Apply Your Knowledge YIPPEE! Match the following:
coronary arteries A. exchange vessels arterioles B. supply blood to the heart tissues veins C. largest veins in the body arteries D. supplies the forearm and hand capillaries E. carry blood toward heart vena cavae F. drain the knees radial artery G. strongest blood vessels popliteal veins H. small branches of arteries ARTERIES: B H E G A C Learning Outcome: Differentiate among the different types of blood vessels and their functions. D F YIPPEE!

30 Blood Pressure The force blood exerts on the inner walls of blood vessels Highest in arteries Lowest in veins Rises and falls as ventricles contract and relax Learning Outcome: Explain blood pressure and tell how it is controlled. In the clinical setting, blood pressure refers to the pressure in arteries. .

31 Blood Pressure Systolic pressure Diastolic pressure Pulse Systole
Ventricles contract Blood pressure in arteries greatest Diastolic pressure Diastole Ventricles relax Blood pressure in arteries lowest Pulse Learning Outcome: Explain blood pressure and tell how it is controlled. Systolic pressure – blood pressure in the arteries when the ventricles contract. Diastolic pressure – blood pressure in arteries when the ventricles relax. Reported as Systolic pressure over diastolic pressure – 120/80 Pulse - created as the artery expands when pressure increases and then subsequently relaxes as blood pressure decreases.

32 Blood Pressure (cont.) Factors affecting blood pressure Cardiac output
Blood volume Vasoconstriction and vasodilation Blood viscosity Learning Outcome: Explain blood pressure and tell how it is controlled. Cardiac output - total amount of blood pumped out of the heart in one minute. As cardiac output increases and decreases, blood pressure increases and decreases. With blood loss, blood pressure falls and vasoconstriction helps to raise blood pressure. If blood pressure is too high, vasodilation decreases the blood pressure. If blood becomes more viscous, blood pressure will decrease.

33 Blood Pressure (cont.) Controlled by the amount of blood pumped out of the heart Starling's law of the heart Blood entering the left ventricle stretches its wall The more the wall is stretched the harder it will contract Learning Outcome: Explain blood pressure and tell how it is controlled. Blood pressure is controlled to a large extent by the amount of blood pumped out of the heart. Blood entering the heard should equal the amount pumped out. Starling’s law of the heart When blood enters the left ventricle, the wall of the ventricle is stretched. The more the wall is stretched, the harder it will contract and the more blood it will pump out. If only a small amount of blood enters the left ventricle, it will not be stretched very much and will not contract very forcefully.

34 Blood Pressure (cont.) Baroreceptors Help regulate blood pressure
Located in the aorta and carotid arteries Send information to cardiac center in the medulla oblongata Learning Outcome: Explain blood pressure and tell how it is controlled. Baroreceptors measure blood pressure. The cardiac center increases or decreases the heart rate to regulate blood pressure based on information from the baroreceptors.

35 Good Answer! Apply Your Knowledge
What is the difference between the systolic pressure and diastolic pressure? ANSWER: Systolic pressure is the result of the contraction of the ventricles increasing the pressure in the arteries. Diastolic pressure is the result of the relaxation of the ventricles lowering the pressure in the arteries. Learning Outcome: Explain blood pressure and tell how it is controlled. Good Answer!

36 Diseases and Disorders of the Cardiovascular System
Chest pain Cardiac causes Myocardial infarction Angina Pericarditis Coronary spasm Non-cardiac causes Heartburn Panic attacks Pleurisy Costochondritis Pulmonary embolism Sore muscles Broken ribs Learning Outcome: Describe the causes, signs and symptoms, and treatments of various diseases and disorders of the cardiovascular system. Refer to Educating the Patient Feature – Chest Pain Take all complaints of chest pain seriously!

37 Diseases and Disorders of the Cardiovascular System (cont.)
Description Aneurysm A ballooned, weakened arterial wall Arrhythmias Abnormal heart rhythms Endocarditis Inflammation of the innermost lining of the heart, including valves Myocarditis Inflammation of the muscular layer of the heart Learning Outcome: Describe the causes, signs and symptoms, and treatments of various diseases and disorders of the cardiovascular system. Aneurysm Most common locations are the aorta and arteries in the brain, legs, intestines, and spleen. Most causes are unknown but may include atherosclerosis , congenital conditions, or traumatic injury Arrhythmias Most common – atrial fibrillation which is a sporadic and rapid beating of the atria. Most serious type of heart arrhythmia is ventricular fibrillation, which produces ineffective contractions of the ventricles because electrical impulses of the cardiac conduction system do not flow correctly through the heart. Endocarditis – caused by bacterial infections Myocarditis – caused by a viral infection, but it also may be caused by exposure to certain chemicals, allergens, and bacteria.

38 Diseases and Disorders of the Cardiovascular System (cont.)
Description Pericarditis Inflammation of the membranes that surround the heart (pericardium) Congestive heart failure Weakening of the heart over time; heart is unable to pump enough blood to meet body’s needs Coronary artery disease (CAD) Atherosclerosis; narrowing of coronary arteries caused by hardening of the fatty plaque deposits within them Learning Outcome: Describe the causes, signs and symptoms, and treatments of various diseases and disorders of the cardiovascular system. Pericarditis Most commonly caused by complications of viral or bacterial infections. May also result from heart attacks and chest injuries. Congestive heart failure – there are many risk factors for this condition as well as congenital heart defects and drugs that weaken the heart Coronary artery disease (CAD) Produced by the buildup of fat, cholesterol, and calcium in the arteries. Risk factors include high levels of LDL cholesterol in the blood, a diet high in fat and cholesterol, smoking, high blood pressure, obesity, a lack of exercise, and diabetes mellitus Refer to CONNECT to see animations about Heart Failure Overview, Left- Side Heart Failure, Right-Side Heart Failure, and Coronary Artery Disease

39 Diseases and Disorders of the Cardiovascular System (cont.)
Description Hypertension High blood pressure; consistent resting blood pressure equal to or greater than 140/90 mm Hg Mitral valve prolapse Valve falls into the left atrium during systole; prevents proper closing Murmurs Abnormal heart sounds Learning Outcome: Describe the causes, signs and symptoms, and treatments of various diseases and disorders of the cardiovascular system. Hypertension Increases a person’s risk of heart attack, stroke, heart failure, and kidney failure Known causes and risk factors include narrowing of the arteries, various medications, kidney disease, endocrine disorders, pregnancy, drug use sleep apnea, obesity, smoking, a high-sodium diet, excessive alcohol consumption, stress, and diabetes. Mitral valve prolapse (MVP) Blood may flow back into the atrium; may become worse over time Increases the risk of heart valve infections and endocarditis. The cause is unknown in most cases. It may be hereditary or due to autonomic nervous system disorders. Murmurs Murmurs are graded from 1 to 6, 1 being barely audible. Not all the causes of heart murmurs are known. In children, the failure of the foramen ovale or ductus arteriosis to close completely after birth can cause murmurs. Other causes include stress and defective heart valves. Refer to CONNECT to see an animation about Hypertension

40 Diseases and Disorders of the Cardiovascular System (cont.)
Description Myocardial infarction Heart attack; damage to cardiac muscle due to a lack of blood supply Stenosis of the heart valves The valve does not fully open; aortic stenosis, mitral stenosis Thrombophlebitis Blood clots and inflammation develop in a vein Varicose veins Twisted, dilated veins Learning Outcome: Describe the causes, signs and symptoms, and treatments of various diseases and disorders of the cardiovascular system. Myocardial infarction The causes and contributing factors include blockage of coronary arteries as a result of atherosclerosis or a blood clot. Drugs such as cocaine also can cause coronary arteries to spasm. Stenosis of the heart valves Blood flow from the heart is decreased, and pressure inside the left ventricle is increased. Congenital or as a result of rheumatic fever. Thrombophlebitis If the blood clot breaks loose becoming an embolus, it can cause a pulmonary embolism, heart attack, or CVA (stroke). Many risk factors including prolonged inactivity, oral contraceptives and others Varicose veins If they occur in the rectum – hemorrhoids May be caused by prolonged sitting or standing, damage to valves in the veins, a loss of elasticity in the veins, obesity, pregnancy, oral contraceptives, or hormone replacement therapy. Family history may also be a cause.

41 Bravo! Apply Your Knowledge True or false:
A myocardial infarction results from a lack of oxygen to the cardiac muscle Myocarditis is inflammation of the innermost lining of the heart. A potentially fatal arrhythmia is ventricular fibrillation. Murmurs are abnormal heart rhythms. ANSWER: T F Endocarditis T Learning Outcome: Describe the causes, signs and symptoms, and treatments of various diseases and disorders of the cardiovascular system. sounds F Bravo!

42 In Summary 26.1 The structures of the heart include the pericardium, epicardium, myocardium, and endocardium. The chambers of the heart consist of the upper atria and the lower ventricles. The septa are the interatrial, interventricular, and atrioventricular. The four valves within the heart are the tricuspid, the bicuspid, the pulmonary semilunar, and the aortic semilunar valves.

43 In Summary (cont.) 26.2 One cardiac cycle consists of one complete heartbeat. The atria contract and relax together, and the ventricles contract and relax together. As each chamber contracts, associated valves open and close to control the flow of blood through the heart. Contractions are initiated by the cardiac conduction system. 26.2 One cardiac cycle consists of one complete heartbeat. The atria contract and relax together, and the ventricles contract and relax together. As each chamber contracts, associated valves open and close to control the flow of blood through the heart. Contractions are initiated by the cardiac conduction system, which consists of the sinoatrial node, the atrioventricular node, the bundle of His, and Purkinje fibers.

44 In Summary (cont.) 26.3 Pulmonary circulation: Right atrium  tricuspid valve  right ventricle  pulmonary semilunar valve pulmonary trunk  pulmonary arteries  lungs pulmonary veins  left atrium. Systemic circulation: Left atrium  bicuspid valve left ventricle  aortic semilunar valve  aorta  arteries  arterioles  capillaries  venules  veins  venae cavae  right atrium.

45 In Summary (cont.) 26.4 Types of blood vessels include arteries and arterioles, which bring blood from the heart to the body; capillaries, which act as the connectors between the arterioles and venules. The largest artery in the body is the aorta. Others arteries are listed in the chapter. The largest veins in the body are the superior and inferior venae cavae. Others veins are listed in the chapter. 26.4 Types of blood vessels include arteries and arterioles, which bring blood from the heart to the body; veins and venules, which carry blood back from the body to the heart; and capillaries, which act as the connectors between the arterioles and venules. The largest artery in the body is the aorta. Other major arteries include lingual, facial, occipital, maxillary, ophthalmic, axillary, brachial, ulnar, radial, intercostals, lumbar, external iliac, common iliac, femoral, popliteal, and tibial. The largest veins in the body are the superior and inferior venae cavae. Other major veins are jugular, brachiocephalic, axillary, brachial, ulnar, radial, intercostals, azygos, gastric, splenic, mesenteric, hepatic portal, hepatic, iliac, femoral, popliteal, and saphenous.

46 In Summary (cont.) 26.5 Blood pressure is the force exerted on the inner wall of blood vessels by blood as it flows through vessels. It is highest in arteries and lowest in veins. Clinically, blood pressure refers to the force of blood within the arteries. Blood pressure is largely controlled by the amount of blood pumped out of the heart, but various other events also may raise and lower blood pressure.

47 In Summary (cont.) 26.6 Many different types of cardiac and blood diseases are described within this chapter. The signs, symptoms, and treatments are as varied as the diseases themselves. The last section of this chapter outlines the most common of these diseases, their signs and symptoms, as well as their treatments.

48 End of Chapter 26 Your work is to discover your world and then with all your heart give yourself to it. ~ Buddha


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