1. Bojana Gardijan 4th year March 16, 2010 Mentor: A. Žmegač Horvat

2.  destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle  part of acute coronary syndrome, ACS  non- STEMI non ST-elevation MI  STEMI ST-elevation MI

3.  diabetes  hyperlipoproteinemia, especially high LDL and low HDL  high blood pressure  family history of ischemic heart disease  obesity BMI>30 kg/m²  age M>45, F>55  stress  alcohol

4.  a manifestation of coronary artery disease, also called ischemic heart disease  most common triggering event: disruption of an atherosclerotic plaque in an coronary artery clotting cascade sometimes results in total occlusion of the artery

5.  chest pain (typically radiating to the left arm or left side of the neck)  shortness of breath (dyspnea)  nausea, vomiting  palpitations  sweating  anxiety

6.  history and physical examination  EKG  CBC  cardiac markers, preferably troponin T (and complete biochemistry)  differential diagnosis includes pulmonary embolism, aortic dissection, pericardial effusion causing cardiac tamponade, tension pneumothorax, pancreatitis and esophageal rupture

7.  MONA as soon as possible morphine, oxygen, nitrates, aspirin  clopidogrel, heparin, eptifibatide  procedure of choice : PCI (percutaneous coronary intervention) if unavailable: fibrinolysis  postinfarctial therapy: SAAB statins, ACEI, aspirin, beta blockers

8.  varies greatly, depending on a person’s health, the extent of the heart damage and the treatment given  time to reperfusion is of great importance  a quick reaction saves lives

10.  http://en.wikipedia.org/wiki/Myocardial_infar ction  http://www.escardio.org