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Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity Yun Sok Lee, Jung-whan Kim, Olivia Osborne,

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Presentation on theme: "Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity Yun Sok Lee, Jung-whan Kim, Olivia Osborne,"— Presentation transcript:

1 Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity Yun Sok Lee, Jung-whan Kim, Olivia Osborne, Da Young Oh, Roman Sasik, Simon Schenk, Ai Chen, Heekyung Chung, Anne Murphy, Steven M. Watkins, Oswald Quehenberger, Randall S. Johnson, Jerrold M. Olefsky Cell Volume 157, Issue 6, Pages 1339-1352 (June 2014) DOI: 10.1016/j.cell.2014.05.012 Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

2 Figure 1 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

3 Figure 2 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

4 Figure 3 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

5 Figure 4 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

6 Figure 5 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

7 Figure 6 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

8 Figure 7 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

9 Figure S1 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

10 Figure S2 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

11 Figure S3 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

12 Figure S4 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

13 Figure S5 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

14 Cell 2014 157, 1339-1352DOI: (10.1016/j.cell.2014.05.012) Copyright © 2014 Elsevier Inc. Terms and Conditions Terms and Conditions

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