1. Pathology of the ovary

2. WHO CLASSIFICATION OF TUMORS OF THE OVARY (2003) 1. Surface epithelial-stromal tumors Serous tumors - malignant: adenocarcinoma, surface papillary adenocarcinoma, adenocarcinofibroma - borderline: papillary cystic tumor, surface papillary tumor, adenofibroma, cystadenofibroma - benign: cystadenoma, adenofibroma, cystadenofibroma, surface papilloma

3. Mucinous tumors - malignant: adenocarcinoma,adenocarcinofibroma - borderline: intestinal type, endocervical-like - benign: cystadenoma, adenofibroma, mucinous cystic tumor with pseudomyxoma peritonei Endometrioid tumors including variants with squamous differentiation - malignant: adenocarcinoma,adenocarcinofibroma, malignant mullerian mixed tumor (carcinosarcoma) - borderline: cystic tumor, adenofibroma - benign: cystadenoma, adenofibroma

4. Clear cell tumors - malignant: adenocarcinoma, adenocarcinofibroma - borderline: cystic tumor, adenofibroma - benign: cystadenoma, adenofibroma Transitional cell tumors - malignant: transitional cell carcinoma (non-Brenner type), malignant Brenner tumor - borderline: Brenner tumor (proliferating type) - benign: Brenner tumor Squamous cell tumors malignant and benign Mixed epithelial tumors malignant,borderline,benign Undifferentiated and unclasified tumors

5. 2. Sex cord-stromal tumors Granulosa-stromal cell tumors - Granulosa cell tumor group: adult, juvenile - Thecoma-fibroma group: thecoma, fibroma, fibrosarcoma Sertoli-stromal cell tumors - Sertoli-Leydig stromal cell group Sex cord-stromal tumors of mixed or unclassified cell types sex cord tumor with annular tubules, gynandroblastoma Steroid cell tumor

6. 3. Germ cell tumors Primitive germ cell tumors - Dysgerminoma - yolk sac tumor - embryonal carcinoma -polyembryoma - non-gestational choriocarcinoma Biphasic or triphasic teratoma - immature teratoma - mature teratoma dermoid cyst

7. Monodermal teratoma - thyroid tumor group struma ovarii - carcinoid group - neuroectodermal tumor group -carcinoma group adenocarcinoma,squamous cell carcinoma - melanocytic group - sarcoma group - etc....

8. 4. Germ cell sex cord-stromal tumors 5. Tumors of the rete ovarii 6. Miscellaneous tumors 7. Tumor-like conditions - luteoma of pregnancy - stromal hyperthecosis - stromal hyperplasia - fibromatosis - massive ovarian edema - others 8. Lymphoid and hematopoietic tumors 9. Secondary tumors

9. Surface epithelial-stromal tumors etiology risk factors

10. Benign serous tumors

11. Benign serous tumors gross and microscopic features

12. Borderline serous tumors

13. Serous adenocarcinoma

14. Serous adenocarcinoma gross and microscopic features

15. Benign mucinous tumors

16. Benign mucinous tumors gross and microscopic features

17. Borderline mucinous tumors

18. Mucinous adenocarcinoma

19. Mucinous adenocarcinomas gross and microscopic features

20. Pseudomyxoma peritonei

21. Endometrioid tumors

22. Endometrioid adenocarcinoma

23. Endometrioid adenocarcinoma gross and microscopic features

24. Sex cord-stromal tumors Granulosa cell tumor group

25. Granulosa cell tumor group Adult granulosa cell tumor

26. Juvenile granulosa cell tumor

27. Thecoma-fibroma group Thecoma

28. Thecoma

29. Fibroma

30. Germ cell tumors

31. Malignant transformation of germ cell Mature Benign mature cystic teratoma struma ovarii Malignant squamous carcinoma carcinoid thyroid carcinoma Embryonal (multipotential) Undifferentiated dysgerminoma Primitive embryonal carcinoma Somatic immature teratoma Trophoblast choriocarcinoma Extraembryonic yolk sac carcinoma

32. Mature teratoma

33. Mature teratoma dermoid cyst

34. Monodermal teratomas

35. Immature (malignant) teratomas

36. Dysgerminoma