1. Neil Cowles, Chief Executive Officer OPEN SOURCE SOLUTIONS FOR HEALTHCARE INFORMATION Tolven Update February 2011

2. T OLVEN H EALTHCARE I NNOVATIONS Customer and Business Growth Tolven Adoption North America Primary care clinics Specialty clinics Clinical trial data management Health Information Exchange Hospital EMR system Consumer health records Women’s health clinics Europe Personal health records Health Information Exchange Long Term care Acute care health summaries Patient questionnaires and surveys Asia National infrastructure for health records

3. Partner Strategy T OLVEN H EALTHCARE I NNOVATIONS Tolven Partner Channels National and regional system integrators USA Europe Asia “Blue Chip” retail corporation Academic medical centers North America Europe Subject matter expert organizations Life science Cancer Pharmacy

4. Company Growth T OLVEN H EALTHCARE I NNOVATIONS Tolven Growth Series A Closed in Q4 2010 Validation of company vision and financial security Accelerated staffing growth Plans for new service offerings Key infrastructure improvements

5. T OLVEN H EALTHCARE I NNOVATIONS Transcend Summery TRANSCEND Electronic Clinical Research Forms Comprehensive Clinical Notes Integration caBIG Integration Hub (caXchange) caTissue caArray Randomization Service Data Coordination Automated workflows Trial Summary Record Adverse Event Reports Data Export and Exchange

6. Technology and Application Update Technology Security Open AM Single sign-on OAuth Application Server Glassfish Applications ONC Meaningful Use ePrescribing Surescripts gateway Appointment scheduling Integration with billing T OLVEN H EALTHCARE I NNOVATIONS Logo

7. Certification ONC Certification Meaningful Use Phase 1:29 scripts scheduled for Q2 2011 Phase 2:Completion of certification Q3 2011 ePrescribing and Surescripts Certification Clinical decision support with FDB integration Certification process underway T OLVEN H EALTHCARE I NNOVATIONS

8. Future Plans Deployment VMware Simplified deployment Improved documentation Technology Google WebToolkit (GWT) Updated database, application server and operating systems Matrix for supported technologies Applications Enhancements under SAIC/NCI contract Tolven as the core for the caBIG CIS reference implementation CBIIT standards and specification adherence caGrid 2.0 and semantic infrastructure specifications T OLVEN H EALTHCARE I NNOVATIONS Logo