2. New Investigator (NI)  Has not been PI on a significant NIH research grant (R01)  Can have obtained small research grants (e.g., R03, R21), previous K or F grants, or been on T32 Early Stage Investigator (ESI)  A new investigator within 10 years of doctorate or completing residency Status of NI or ESI defined in your eRA Commons profile & check with RMG at Stanford http://grants1.nih.gov/grants/new_investigators/index.htm

4. National Research Service Awards (NRSAs)  Training Grants (T32, 34, 35, 90)  Fellowship Grants (F30-33 series) for early training  US Citizen, Non-Citizen National, or lawfully admitted for Permanent Residence  Must have a PhD or MD or comparable doctoral degree from an accredited domestic or foreign institution

5. ProgramDescription F30 Predoctoral Fellowship Combined MD/PhD and other dual-doctoral degree training. F31 Predoctoral Fellowship Dissertation research and training in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. F32 Individual Postdoctoral For individuals to broaden their scientific background and extend their potential for research in specified health-related areas. F33 NRSA for Senior Fellows To support experienced scientists who wish to make major changes in the direction of their research careers or who wish to broaden their scientific background by acquiring new research capabilities as independent investigators. F32s are mostly unsolicited http://grants.nih.gov/training/f_files_nrsa.htm

6. F32 Section Page Limit Specific Aims1 Research Strategy6 Respective Contributions1 Selection of Sponsor and Institution1 RCR1 Goals for Fellowship Training and Career1 Activities Planned Under This Award1 Doctoral Dissertation and Other Research Experience2 Sponsor and Co-Sponsor6 Biographical Sketch4

7.  F32s are training awards, not research awards  Major review considerations are your:  potential for a productive career  need for the proposed training  the degree to which the research training proposal, the sponsor, and the environment will satisfy those needs and develop the career

8. http://grants.nih.gov/training/f_files_nrsa.htm

10. http://grants.nih.gov/training/careerdevelopmentawards.htm

12.  US Citizens, Non-Citizen Nationals, Permanent Residents (except K99/R00); not renewable (except K24)  Must devote a minimum of 75% effort to research and career development activities  3-5 years of support  Principal Investigators on R03 or R21 are eligible to apply (except K99/R00)  Principal Investigators on R01 or subproject Principal Investigators on a P01 are not eligible to apply

13. ProgramDescription K01 Mentored Research Scientist Development Award Career development in a new area of research K08 Mentored Clinical Scientist Research Development Award Career development for those with clinical doctoral degree in biomedical/behavioral research, including translational research—if patient research, see K23. K07 Academic Career Award Developmental of junior candidates; leadership for individuals in improving curricula and enhancing research capacity. K22 Career Transition Award—Research or Clinical Scientist Support to an individual postdoctoral fellow in transition to a faculty position. K23 Mentored Patient-Oriented Research Career Development Award Development of the independent research scientist for patient research—if not patient-oriented research in biomedical area, see K08. K25 Mentored Quantitative Research Career Development Award To foster interdisciplinary collaboration in biomedical research by supporting career development experiences for scientists with quantitative and engineering backgrounds. K99/R00 NIH Pathway to Independence Award. Provides 5 years’ support in 2 phases: I.1-2 years of mentored support for highly promising postdoctoral fellows. II.Up to 3 years of independent support contingent on securing an independent research position.

14. ProgramDescription K22Career Transition Award Support to an individual postdoctoral fellow in transition to a faculty position. K99/R00 NIH Pathway to Independence Award. Provides 5 years’ support in 2 phases: I.1-2 years of mentored support for highly promising postdoctoral fellows II.Up to 3 years of independent support contingent on securing an independent research position.

15.  K99: Mentored research experience for up to 2 years  R00: Transition to research independence as junior faculty for up to 3 years  Applicants: no more than 5 years of postdoctoral research training at the time of initial application or resubmission  Non-US citizens may apply, but institution must be domestic  Transition to R00 phase requires offer and acceptance of tenure-track, full-time assistant professor position (or equivalent) 15

16. 16 K Contents SectionMaterial Requested Candidate Information & Career Development Plan Candidate background Career Goals and Objectives Career Development & Training Activities Training in Responsible Conduct of Research Research PlanSpecific Aims + Research Strategy Statements of SupportStatements by Mentor, Co-Mentor, Consultants Environment and Institutional Commitment to Candidate Description of Institutional Environment Institutional Commitment to Candidates Research Career Development Letters of Reference 3-5 reference letters not from the Mentor/Co-Mentor From established scientists (referees) that address candidate’s qualifications, training, interests and potential for becoming an independent scientist 12 pg

17. Candidate Mentor/Consultants Environment/Institution Research StrategyCareer Development Plan

18. Postdoc or Residency Grad or Med School Predoc T32 Predoc T32 NRSA Postdoc F32 Ment Research K01 Pathway to Independence (K99/R00) Independent Scientist K02 Midcareer Patient- Oriented K24 Early Middle Senior Postdoc T32 Senior Scientist Award K05 Ment Clinical K08 Ment Patient- Orient K23 Ment Quant RCDA K25 NRSA Predoc F30, F31 Small Research Grant R03 Exploratory/Development Grant R21 Research Project Grant R01 U-Series Cooperative Grants SBIR, STTR R41/R42 P-Series Program Project/Center Career Transition Award K22 NRSA Senior Fellow F33 NRSA Senior Fellow F33

19. GrantF32K01K99R01 NCI18%55%17%14% NIAID19.6%58%18%19% NHLBI21%17%30%14.8%

20. A valuable tool to access any F or K grant Demonstration