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Brain Cancer Presented by Amal Oladuja and Michelle Garro
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Introduction Brain Cancer
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Anatomy Brain cancer can spread to any tissue in the brain Brain Anatomy
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Genes Involved Glioblastoma –C/EBP –Stat3
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Symptoms Headaches (severe in the morning) Nausea and vomiting Vision and Hearing problems
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Diagnosis Imaging tests: CT or MRI Biopsy Spinal Tap
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Complications Problems with walking and balance Memory problems Muscle jerking and twitching Numbness in arms or legs Seizures
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Contributing Factors Radiation to head Genetic Risk HIV Infection Smoking Environmental Toxins
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Forms Brain tumors can be: –Benign –Malignant Two Main Types: –Primary –Metastatic
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Stages Grade 1 –Slow growth –Easily treated Grade 2 –Tumor is bigger –Has potential to become more dangerous Grade 3 –Aggressive tumor –Cancer cells can be easily distinguished from brain cells Grade 4 –Tumor is perilous –Difficult to treat
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Stages of Brain Cancer
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Treatment Individualized for each patient: Surgery –W/Knife –W/O knife: Stereotactic Radiosurgery Radiation Chemotherapy
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Side Effects of Surgery Brain swelling Damage to tissue Change in mental status Weakness in muscles Changes in brain functions
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Side Effects of Radiation Therapy Skin damage and skin sensitivity Hair loss
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Side Effects of Chemotherapy Hair loss Nausea Vomiting Weakness Damaged kidney and reproductive organs
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Prevalence Gender: –Females: 0.54% risk of being diagnosed* 0.41% chance of dying from tumor –Males: 0.66% risk of being diagnosed* 0.5% chance of dying from tumor Age: –60% of brain cancer patients are 50-70 years old
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Prevalence (cont’d) Males more at risk Middle aged and older People of European descent Workers in factories involving toxic chemicals
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Epidemiology 15-20 cases out of 100,00 people ~17,000 diagnosed w/primary cancer each yr in US ~13,000 of those diagnosed die from brain cancer
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Prevention Avoid toxic chemicals and environmental toxins Avoid HIV infections No smoking! *Lessen cell phone use
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Awareness Brain Tumor Foundation International Brain Tumor Alliance Walk Around The World for Brain Tumors International Brain Tumor Awareness Week
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Sources http://www.nlm.nih.gov/medlineplus/braincancer.html http://www.emedicinehealth.com/brain_cancer/page8_em.htm http://news.bbc.co.uk/2/hi/8426015.stm http://emedicine.medscape.com/article/1157902-overview http://www.csmc.edu/5192.html http://www.ehow.com/about_5084861_stages-brain-cancer.html http://www.abta.org/ http://images.healthcentersonline.com/cancer/images/article/BrainAnatomy_captione d.jpghttp://images.healthcentersonline.com/cancer/images/article/BrainAnatomy_captione d.jpg http://www.cancer.gov/cancertopics/factsheet/Sites-Types/metastatic http://www.virtualtrials.com/symptoms.cfm http://www.decodeme.com/risk-for-brain-cancer-glioma http://www.revolutionhealth.com/conditions/cancer/brain-cancer/facts-statistics http://kidshealth.org/kid/htbw/brain.html http://www.braintumorfoundation.org/ http://www.theibta.org/ http://www.gfmer.ch/selected_images_v2/detail_list.php?offset=15&cat1=3&cat3=96&stype=d
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