1. Ocular Aberrations and Quality of Vision with Aspheric Single-Piece and Spherical Multi- Piece IOL: Contra lateral Comparative Study Ahmed Assaf MD, FRCSEd the author of this poster have received travel expense reimbursement from AMO Company

2. Intraocular Lenses (IOLs) Spherical aberration (SA) and coma are the commonest HOAs to affect quality of vision Aspheric IOLs with negative SA aim to balance the positive corneal SA, thus reducing the amount of total ocular SA with respect to conventional spherical IOLs

3. Spherical 3-piece (Sensar AR40e) IOL

4. Aspheric (Tecnis 1-P, Tecnis ZCB00) IOL OPTIC of the lens has negative spherical aberration of 0.27µm to compensate for average corneal positive spherical aberration

5. Purpose of the Study To test visual outcomes and higher ocular aberrations of aspheric (Tecnis 1-P) IOL against spherical (Sensar AR40e™) biconvex multi-piece IOL. Both lenses are made of hydrophobic acrylic and by the same company (AMO, Abbott Medical Optics, Santa Ana, CA)

6. P=0.81 P<0.001 Pre Operative Post Operative Micron 0.28 ±0.08 0.29 ±0.09 0.006 ±0.03 0.42 ±0.11 VISX ™ WaveScan Wavefront System Spherical(Sensar) Aspheric (Tecnis 1-P) Spherical(Sensar) OCULUS Optikgeräte GmbH, Easygraph Aspheric (Tecnis 1-P) n=28 Spherical Aberration

7. P=0.88 P=0.76 Pre Operative Post Operative Micron 0.167 ±0.09 0.158 ±0.085 0.154 ±0.071 0.151 ±0.071 VISX ™ WaveScan Wavefront System Spherical(Sensar) Aspheric (Tecnis 1-P) Spherical(Sensar) OCULUS Optikgeräte GmbH, Easygraph Aspheric (Tecnis 1-P) Coma

8. P=0.38 Pre Operative Post Operative Micron 0.185 ± 0.12 0.162 ± 0.12 0.157 ± 0.13 0.145 ± 0.12 VISX ™ WaveScan Wavefront System Spherical(Sensar) Aspheric (Tecnis 1-P) Spherical(Sensar) OCULUS Optikgeräte GmbH, Easygraph Aspheric (Tecnis 1-P) P=0.47 Trefoil

9. Aspheric IOL (mean±SD)Spherical IOL (mean±SD) P Sphere (D) -0.01D±0.60-0.06D±0.67 P=0.67 Cylinder (D) -0.57D±0.30-0.55D±0.32 P=0.84 Spherical Equivalent (D) -0.30D±0.66-0.34D±0.74 P=0.69 LogMAR BCVA0.046±0.010.053±0.09P=0.78

10. Log Contrast Sensitivity (CS) Cycles per Degree (CPD) n=28 VectorVision TM 1000E Chart 85cd/m 2 6 wks postop. P=0.043

11. Log Contrast Sensitivity (CS) Cycles per Degree (CPD) P<0.001 n=28 VectorVision TM 1000E Chart 6cd/m 2 6 wks postop.

12. Conclusion Aspheric (Tecnis 1-P) IOL significantly reduce ocular spherical aberration. This is reflected as improved quality of vision mainly in mesopic conditions.

13. No significant differences regards ocular coma and trefoil of aspheric single piece IOL compared to spherical multi-piece IOL. Thank You Conclusion