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A 41 year old African patient with „multifocal neurology“ Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology
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A 41 year old female patient originally from West Africa presented with 3-week history of generalized weakness. Clinical examination presented quadriparesis, urinary incontinence and reduced level of consciousness. Maroski et al.
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The imaging of neuroaxis revealed multiple bilateral cerebral lesions including basal ganglia and midbrain. Spinal cord imaging showed lesions in conus medullaris (Figure). The HIV test was reactive with a CD4 count of 10 cells/ µL (normal range: 700- 1 200/ µL). CSF PCR for Toxoplasma gondii was positive. CSF cryptococcal antigen, fungal and mycobacterial cultures, EBV-PCR and M.tuberculosis-PCR were negative. Conus medullaris involvement is an uncommon manifestation of toxoplasmosis in advanced HIV. Maroski et al.
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