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Serotonin Syndrome: The ten minute version Russell Berger, MD.

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Presentation on theme: "Serotonin Syndrome: The ten minute version Russell Berger, MD."— Presentation transcript:

1 Serotonin Syndrome: The ten minute version Russell Berger, MD

2 Clinical Triad Altered mental status Dysautonomia Hyperreflexia (lower extremity>upper extremity)

3

4 Relevant History New serotonergic agent(usually in addition to one old agent) Rapid onset of symptoms

5

6 What are some of the more common serotonergic agents Tramadol Demerol TCA’s SSRI’s Lithium MAOi’s Linezolid(yes, the abx) Trazodone Valproic acid Tryptophan St John’s Wort Ginseng

7 Complications of Serotonin Syndrome Seizures Rhadbomyolysis Hyperthermia Metabolic Acidosis Renal Injury Death

8 Treatment Options Benzodiazepines – No risk Cyproheptadine(5HT-2A antagonist) – Anticholinergic

9 The diagnostic dilemma

10 Questions

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