1. Susan Warren, MD 202-994-0033 psyslw@gwumc.edu

2. Early Risk Factors for Anxiety Disorders Neurophysiological risk factors including startle, EEG and sleep Family relationship factors including the attachment relationship

3. Infants of Anxious Mothers In previous research studied 4 month and 14 month infants of mothers with panic disorder and normal controls Found that infants of mothers with panic disorder had elevated baseline salivary cortisol and more disturbed sleep Mothers with panic disorder showed less sensitivity towards their infants

4. Infants of Anxious Mothers Recruited more than 200 mothers with anxiety disorders and normal controls Infants participate at 4 months, 14 months and 2 years of age Examining child neurophysiology, temperament, and parenting behaviors that predict later child diagnoses

5. Anxious Toddlers In previous research studied diagnostic criteria for anxiety disorders in toddlers Toddlers were mostly 2-years-old Modifications to adult social phobia criteria showed good convergent and discriminant validity but modifications to adult generalized anxiety disorder did not

6. Anxious Toddlers Recruited more than 300 toddlers from the general population, some with anxiety disorders Toddlers participate at 2, 3 and 5 years of age Examining child neurophysiology, temperament, and parenting behaviors that predict later child diagnoses

7. Improving Psychiatric Diagnostic Criteria Developing new statistical procedures to test psychiatric diagnostic criteria Will use these new procedures to better define psychiatric diagnoses for young children and adults