1. Cellular Respiration Aerobic and Anaerobic Metabolism

2. Glycolysis takes place in the cytoplasm

3. Glycolysis Simplified (greatly ) If oxygen is available (aerobic), then pyruvate enters the Krebs cycle If oxygen is not available(anaerobic), then pyruvate undergoes fermentation

4. Aerobic respiration

5. Synonymous Terms Krebs cycle Citric acid cycle Tri-carboxylic acid cycle (TCA cycle)

6. Mitochondrial Structure Krebs cycle The Krebs cycle takes place across inner membrane space (matrix) of the mitochondrion

7. ElectronTransport

8. The Role of Oxygen (O 2 ) Oxygen is the terminal (final) electron acceptor ½ O 2 + 2H + + 2e -  H 2 O  Oxygen is needed only in the very LAST step of cellular respiration!

9. Mitochondrial Structure electron transport Infoldings (cristae) increase the area of membrane surface available for electron transport

10. Aerobic Respiration C 6 H 12 O 6 + 6O 2 → 6CO 2 + 6H 2 O + 38 ATP  The Krebs cycle and electron transport take place in the mitochondria  The Krebs cycle and electron transport maximize ATP yield  38 ATP vs. 2 ATP for fermentation

11. Anaerobic Respiration (Alcohol Fermentation) C 6 H 12 O 6 → 2 CH 3 CH 2 OH + 2 CO 2 + 2 ATP glucose ethyl alcohol carbon dioxide Alcohol fermentation takes place in yeast and some bacteria, and yields only the 2 ATP produced in glycolysis

12. Anaerobic Respiration (Lactic Acid Fermentation) C 6 H 12 O 6 → 2 C 3 H 6 O 3 + 2 ATP glucose lactic acid Lactic acid fermentation takes place in animal cells and some bacteria and fungi; it yields only the 2 ATP produced in glycolysis.