1. Anusorn Cherdthong, PhD 137748 Applied Biochemistry in Nutritional Science Email: anusornc@kku.ac.th E-learning: http://ags.kku.ac.th/eLearning/137748 Protein and Amino Acids

2. Introduction  Organic compound with high MW  Similar CHO, fat but contained S  Growth and repaired  Essential for blood, tissue, enzymes, immune and hormone (Riis, 1983; McDonald et al., 2011)

3. Amino acid characteristics  Are biologically important organic compounds made from amine (-NH 2 ) and carboxylic acid (-COOH) functional groups.  Amino acid, carbon, hydrogen, oxygen, and nitrogen.  20 standard amino acids, 9 of the 20 standard amino acids are called “essential”

4. Amino acid characteristics OpenStax College (2013)

5. Structure of 20 amino acid McDonald et al. (2011)

6. Zwitter amino acid McDonald et al. (2011)

7. Type of amino acids  Neutral nonpolar amino acids  Neutral polar amino acids  Acidic amino acids  Basic amino acids

8. Peptide  >2 amino acids  Dipeptide  2 AA  Tripeptide  3 AA  Polypeptide  >3 AA

9. Peptide bond McDonald et al. (2011)

10. Role of peptide  Glutathione  Oxytocin  Enkephalins  Thyrotropin  Antibiotics

11. Protein characteristics  More than 100 molecule AA  Protein are large biological molecules consisting of one or more chains of amino acid.  Proteins perform a vast array of functions within living organisms  A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups.

12. Protein structure  Primary structure  Secondary structure  Tertiary structure  Quaternary structure OpenStax College (2013)

13. Primary structure such as DNA, RNA or typical intracellular protein

14. Secondary structure such as proteins and nucleic acids (DNA/RNA)

15. Tertiary structure Protein or any other macromolecule is its three- dimensional structure

16. Quaternary structure Arrangement of multiple folded protein or coiling protein molecules in a multi-subunit complex

17. Protein classification  Configuration  Chemical composition  Nutrient composition  Role  Part of protein  Protein in animal science

18. Role of protein  Parts of the body  Transport protein  Cell synthesis  Enzymes  Hormones  Growth  Production  protective protein  Reproductive  Storage protein  Contractile protein

19. Conclusion 1 2 3 Role of AA and protein Types of AA and protein Structure of AA and protein

20. Thank you!