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Chronic Pelvic Pain: A Multifactorial Problem
Tony Thomas MD MRCOG Consultant O&G. Minimal Access Gynaecologic Surgeon & RCOG College Tutor Manor Hospital Walsall Healthcare NHS Trust.
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Aims Define chronic pelvic pain
Cite the prevalence and common etiologies of chronic pelvic pain Describe the symptoms and physical exam findings associated with chronic pelvic pain Discuss the psychosocial issues associated with chronic pelvic pain Discuss the steps in the evaluation and management options for chronic pelvic pain
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Definition Chronic pelvic pain can be defined as intermittent or constant pain in the lower abdomen or pelvis of a woman of at least 6 months in duration , not occurring exclusively with menstruation or intercourse and not associated with pregnancy
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Chronic Pelvic Pain Difficult to diagnose Frustration for patient and
Doctor Difficult to treat Difficult to cure
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Prevalance Chronic pelvic pain presents in primary care as frequently as migraine or low-back pain and may significantly impact on a woman’s ability to function. Overall 15-20% of women aged 18 to 50 yrs have chronic pelvic pain 10-30% of gynecologic visits 10-20% of hysterectomies 30-40% of laparoscopy indications
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Etiology frequently more than one component to chronic pelvic pain
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Etiology Psychological Gastrointestinal Urological Gynecological
Musculoskeletal
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Diagnosis Distribution
Chronic Pelvic Pain 25-50% of women had more than one diagnosis Severity and consistency of pain increased with multisystem symptoms Most common diagnoses: endometriosis adhesive disease irritable bowel syndrome interstitial cystitis Gastrointestinal Urinary Gynecological Unknown 20-30% Diagnosis Distribution Found that diagnoses related to the urinary and GI tracts were more common than gynecological diagnoses. For example, 43% of women with CPP without GI or urologic symptoms had moderate to severe pain; whereas 71% of women with both GI and urological symptoms had moderate to severe pain.
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Gynaecologic Endometriosis Adhesions Chronic PID
Ovarian remnant syndrome Pelvic congestion syndrome Recurrent hemorrhagic ovarian cysts Myomata uteri (degenerating) Uterine retroversion Adenomyosis Pelvic floor and hip muscle pain Visceral hyperalgesia
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Non Gynaecologic Genitourinary Gastrointestinal
Urinary retention Urethral syndrome Interstitial cystitis Gastrointestinal Penetrating neoplasms Irritable bowel syndrome Irritable bowel disease Partial small bowel obstruction Diverticulitis Hernia Neuro muscular and Psychological(Higher incidence in victims of abuse/anxiety disorders)
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Psychological and social issues
Enquiry should be made regarding psychological and social issues which commonly occur in association with chronic pelvic pain; Addressing these issues may be important in resolving symptoms
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Etiology Many women present because they want an explanation for their pain. Often they already have a theory or a concern about the origin of the pain. These ideas should ideally be discussed in the initial consultation.
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History The initial history should include questions about the pattern of the pain and its association with other problems, such as psychological, bladder and bowel symptoms, and the effect of movement and posture on the pain.
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Examination Abdominal and pelvic examination
Focal tenderness, enlargement, distortion or tethering Highly localised trigger points may be identified in the abdominal wall and/or pelvic floor. The sacroiliac joints or the symphysis pubis may also be tender, suggestive of a musculoskeletal origin to symptoms
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Investigations All sexually active women with chronic pelvic pain should be offered screening for sexually transmitted infections (STIs). TVS is an appropriate investigation to identify and assess adnexal masses MRI :Second line investigation useful mainly to identify adenomyosis /mass lesions
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Diagnostic laparoscopy
Regarded in the past as the ‘gold standard’ in the diagnosis of chronic pelvic pain. Becoming a second-line investigation if other therapeutic interventions fail. Diagnostic laparoscopy may have a role in developing the woman’s beliefs about her pain.
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Role of CA 125 Women reporting any of the following symptoms persistently or frequently (more than 12 times per month) – bloating, early satiety, pelvic pain or urinary urgency or frequency – should have a serum CA125 measurement taken. Particularly in women over the age of 50 years, any new IBS symptoms should prompt such action.
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Therapeutic Options Women often present because they seek an explanation for their pain The assessment process should allow enough time for the woman to be able to tell her story . This may be therapeutic in itself A pain diary may be helpful in tracking symptoms or activities associated with the pain Where pain is strikingly cyclical and no abnormality is palpable at vaginal examination, a therapeutic trial of ovarian suppression may be more helpful than a diagnostic laparoscopy In suspected IBS : trial with antispasmodics and dietary modification Appropriate analgesia
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Treatment Analgesics NSAIDS including COX-2 inhibitors
Few adequately powered clinical trials have addressed chronic pelvic pain Opioids are increasingly used but randomized trials suggest no improvement in functional or psychological status with increased risk in addiction
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The Pelvic Witch Hunt
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Surgical Arsenal Excision/Ablation of endometriosis
Division of Dense/Vascular Adhesions Ovarian cystectomy Unilateral/Bilateral Salphingo oophorectomy Total Laparoscopic Hysterectomy Unlikely to be beneficial :LUNA, Presacral neurectomy, uterine suspension
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Combined OCP Consider the combined oral contraceptive (COC) pill, first-line. Monophasic COCs containing 30–35 micrograms of ethinylestradiol, and either norethisterone or levonorgestrel, are usually the first choice. NICE suggests a three month trial of conventional treatment, then switching to tricycling after three months if necessary. Some women may find continuous use helpful.
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Combined OCPs Suppress ovulation
Stabilize estrogen and progesterone levels Abrogate menstrual increases in prostaglandin levels Useful for endometriosis-associated chronic pelvic pain
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Progestins Effectively decreases pain from endometriosis and pelvic congestion syndromes Medroxyprogesterone acetate(10 to 20 mgs /day continuous) proven for pain suppression Adverse effects include weight gain, fluid retention, depression, breakthrough bleeding Mirena® intrauterine device shown to be effective in reducing pain and may be considered alternative to hysterectomy in adenomyosis patients
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Physiotherapy Electrotherapy, fast and slow twitch exercises of the striated muscles of the pelvic floor, manual therapy of myofascial trigger points
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Psychotherapy Many suggest various modes of psychotherapy including cognitive therapy, operant conditioning, and behavioral modification appear to be helpful Significant numbers of women with chronic pelvic pain have a history of physical or sexual abuse
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If the only tool you have is a hammer, you tend to see every problem as a nail
Abraham Maslow
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Summary Multifactorial Problem
Women often present because they seek an explanation for their pain The assessment process should allow enough time for the woman to be able to tell her story. This may be therapeutic in itself Often need combination therapies Chronic Pelvic Pain requires patience, understanding and collaboration from both patient and physician Treatment options often multi modal – medical, surgical, physio therapy, cognitive
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Organisations providing further information and/or support
Endometriosis UK [ IBS Network [ Cystitis and Overactive Bladder foundation [ Women’s Health [ or [womenshealth.gov] Pelvic Pain Support Network [ Department of Health Expert Patient Initiative [
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Questions ? Thank you
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