1. Metabolic Energy for Dummies:
A quick look at
Cellular Metabolism
(Energetics)
By Richard Belicek

2. Introduction:
This presentation will cover the general steps that nutrient sources take to be utilized by the body and how energy is created through metabolism.

3. What is Metabolism?
metabolism defined: the total chemical activity and flow of resources that occurs within an organism’s boundary.
Where does it start?

4. Nutrient sources from food.
Foods such as steak, pizza, salad, ice cream and chocolate are broken down into these MACROMOLECULES:
Proteins
Fats
Carbohydrates

5. Macromolecules to Simple Subunits
Proteins = Amino Acids
Fats = Fatty Acids and Glycerol
Carbohydrates = Simple Sugars

6. Subunits follow metabolic pathways
Amino Acids >Protein catabolism = Acetyl CoA >Gluconeogenesis = Pyruvate
Fatty Acids and Glycerol >Oxidation = Acetyl CoA >Gluconeogenesis = Pyruvate
Simple Sugars (Glucose) >Glycolysis =Pyruvate

7. Glycolysis
The sequence of rxns that convert glucose into pyruvate

8. Glycolysis Occurs in the Cytoplasm Aerobic or Anaerobic
Glucose enters the glycolytic pathway
ATP: gross= 4, net= 2
NAD = 2 NADH, transported to the Electron Transport Chain (ETC)

9. The Krebs Cycle
aka:
Tricarboxcyclic Acid Cycle or
Citric Acid Cycle.

10. Krebs Cycle Pyruvate enters cycle 2 cycles per Pyruvate molecule
1 ATP is produced per cycle
NAD and FAD = 6 NADH and 2 FADH2
NADH and FADH2 are transported to the (ETC)

11. Electron Transport Chain

12. Electron Transport Chain
Occurs in the Cristea of the mitochondria
NADH and FADH2 are oxidized
Hydrogen and electrons are carried along chain transfer energy
Electrochemical gradient = ATP
O2 final acceptor = H2O

13. Electron Transport Chain
(1 NADH = 3 ATP, 1 FADH2 = 2 ATP)
Krebs Cycle = 8 NADH = 24 ATP
= 2 FADH2 = 4 ATP
For glycolysis (1 NADH= 2 ATP)
Glycolysis = 2NADH = 4 ATP

14. Overview:

15. Summary Glycolysis Krebs Cycle Electron Transport Chain
Total ATP = 36 net

17. NO
Questions, Thank you.

18. HOORAY!

19. Thank you
Have a good break!!