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2004-2005 Respiratory Review 8 August 2015 8:26 PM
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Abacavir Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI)
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Acebutolol Sympatholytic 1 adrenergic antagonist Class II antiarrhythmic Antihypertensive Antianginal Bronchoconstrictor
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Albuterol Sympathomimetic 2 adrenergic agonist Short acting bronchodilator Used in asthma
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Amikacin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Aminoglycosides Antibiotics Bactericidal protein synthesis inhibitors 30S ribosome Freeze initiation
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Aminophylline Bronchodilator Methylxanthine Phosphodiesterase inhibitor Used in asthma
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Amoxicillin Penicillin antibiotic Cell wall synthesis inhibitor Antiulcer Amino penicillin Inhibits peptidoglycan cross-linking
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Amphotericin B Antifungal Polyene antibiotic Binds to ergosterol and alters permeability Systemic
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Ampicillin Penicillin antibiotic Cell wall synthesis inhibitor Amino penicillin Inhibits peptidoglycan cross-linking
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Atenolol Sympatholytic 1 adrenergic antagonist Antihypertensive Antiarrhythmic Antianginal Bronchoconstrictor
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Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation
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Aztreonam New lactam antibiotic Monobactam
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Bacitracin Antibiotic Cell wall synthesis inhibitor Topical, not a lactam, Inhibits dephosphorylation of bactoprenol
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Beclomethasone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled
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Benzathine penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Inhibits peptidoglycan cross-linking Repository preparation
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Betamethasone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Not by inhalation
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Betaxolol Sympatholytic 1 adrenergic antagonist Antihypertensive Glaucoma medication Bronchoconstrictor
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Bethanecol Cholinomimetic Muscarinic agonist Induces defecation and urination Bronchoconstrictor
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Biltolterol Sympathomimetic 2 adrenergic agonist Bronchodilator
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Bispropolol Sympatholytic adrenergic antagonist Antihypertensive Bronchoconstrictor
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Budesonide Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled
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Captopril Antihypertensive Converting enzyme inhibitor Heart failure treatment Angioedema producer
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Carbenicillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
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Carteolol Sympatholytic adrenergic antagonist Antihypertensive Bronchoconstrictor
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Caspofungin Echinocandin antifungal Blocks synthesis of fungal (1,3)-d-glucan in the cell wall
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Cefaclor Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation Oral
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Cefadroxil Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral
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Cefepime Cephalosporin antibiotic Cell wall synthesis inhibitor 4 th generation CSF penetration
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Cefotaxime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration
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Cefoxitin Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation
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Ceftazidime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation
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Ceftriaxone Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration
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Cefuroxime Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation CSF penetration
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Cephalexin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral
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Cephalosporins Antibiotics lactam Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan
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Cephalothin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral
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Cetirizine Antihistamine H 1 antagonist Non-sedating
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Chloramphenicol Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits peptide bond formation
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Chlorpheniramine Classical antihistamine H 1 antagonist
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Ciprofloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase
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Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation
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Clavulanic acid -lactamase inhibitor Combined with antibacterials
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Clindamycin Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Anaerobic infections
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Clotrimazole Imidazole antifungal Inhibits synthesis of ergosterol Lanosterol 14 demethylase inhibitor
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Cloxacillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking
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Cortisol (Hydrocortisone) Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid
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Cromolyn sodium Mast cell stabilizer Inhibits release of mast cell mediators Used prophylactically in asthma
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Cycloserine Antibiotic Cell wall synthesis inhibitor Secondary TB drug Inhibits formation of Park nucleotide
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Dapsone Sulfone antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Leprosy
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Delavirdine Antiretroviral Non-nucleoside reverse transcriptase inhibitor (NNRTI)
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Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Anti-inflammatory steroid Not by inhalation
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Didanosine Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI) Dideoxyinosine (ddI)
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Diphenhydramine Classical antihistamine Antiemetic H 1 antagonist
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Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
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Ecothiophate Anticholinesterase Vasodilator Bronchoconstrictor Glaucoma treatment
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Edrophonium Anticholinesterase Vasodilator Diagnostic for myaesthenia gravis Bronchoconstrictor
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Efavirenz Antiretroviral Non-nucleoside reverse transcriptase inhibitor (NNRTI)
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Enalapril Antihypertensive Converting enzyme inhibitor Angioedema producer
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Enfuvirtide (T-20) Antiretroviral Fusion inhibitor
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Ephedrine Indirect sympathomimetic Vasoconstrictor Bronchodilator Decongestant
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Epinephrine Sympathomimetic and adrenergic agonist Vasoconstrictor Bronchodilator
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Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation
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Esmolol Sympatholytic 1 adrenergic antagonist Class II Antiarrhythmic Antihypertensive Bronchoconstrictor
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Ethambutol Antibiotic Major drug for tuberculosis
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Ethionamide Antibiotic Secondary drug for tuberculosis
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Fexofenadine Antihistamine H 1 antagonist Non-sedating
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Fluconazole Triazole antifungal Inhibits synthesis of ergosterol by inhibiting lanosterol 14 demethylase
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Flucytosine Antifungal Converted by fungi to 5-fluorouracil faulty RNA and DNA synthesis
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Flunisolide Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled
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Fluorinated Quinolones ciprofloxacin, norfloxacin Antibiotics DNA replication inhibitors Inhibit bacterial DNA gyrase
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Fluticasone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled
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Formoterol Sympathomimetic 2 adrenergic agonist Long acting bronchodilator
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Gentamicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Griseofulvin Antifungal Binds to microtubules
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Hydrocortisone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid
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Hydroxyzine Classical antihistamine H 1 antagonist
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Imipenem/Cilastatin New lactam antibiotic Cilastatin inhibits a kidney dipeptidase that inactivates imipenem
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Indinavir Antiretroviral Protease inhibitor (PI)
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Ipratropium Anticholinergic Antimuscarinic Inhaled bronchodilator
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Isoetharine Sympathomimetic adrenergic agonist Bronchodilator
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Isoniazid Antibiotic Inhibits biosynthesis of mycolic acids Major drug for tuberculosis
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Isoproterenol Sympathomimetic adrenergic agonist Vasodilator Bronchodilator
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Itraconazole Triazole antifungal Inhibits synthesis of ergosterol by inhibiting lanosterol 14 demethylase
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Ketoconazole Imidazole antifungal Inhibits synthesis of ergosterol by inhibiting lanosterol 14 demethylase
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Lamivudine Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI)
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Levobunolol Sympatholytic adrenergic antagonist Antihypertensive Bronchoconstrictor
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Linezolid Oxazolidinone antibiotic Protein synthesis inhibitor 50S ribosomal subunit
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Lisinopril Antihypertensive Converting enzyme inhibitor Heart failure treatment Angioedema producer
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Loratidine Antihistamine H 1 antagonist Non-sedating
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Macrolides erythromycin, azithromycin, clarithromycin Antibiotics Bacteriostatic protein synthesis inhibitors 50S ribosome
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Malathion Anticholinesterase Vasodilator Bronchoconstrictor
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Metaproterenol Sympathomimetic 2 adrenergic agonist Bronchodilator Used in asthma
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Methicillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking
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Methylprednisolone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Not by inhalation
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Metipranolol Sympatholytic adrenergic antagonist Bronchoconstrictor
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Metoprolol Sympatholytic 1 adrenergic antagonist Antihypertensive Heart failure medication Bronchoconstrictor
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Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA
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Miconazole Imidazole antifungal Inhibits synthesis of ergosterol by inhibiting lanosterol 14 demethylase
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Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
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Montelukast Leukotriene inhibitor LTR1 and LTD4 antagonist Asthma treatment
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Nafcillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking
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Nedocromil Mast cell stabilizer Inhibits release of mast cell mediators Used prophylactically in asthma
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Neomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation Topical
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Neostigmine Anticholinesterase Vasodilator Treatment for myaesthenia gravis Promotes defecation and urination Bronchoconstrictor
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Netilmicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Nevirapine Antiretroviral Non-nucleoside reverse transcriptase inhibitor (NNRTI)
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Norfloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase
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Nystatin Antifungal Polyene antibiotic Binds to ergosterol & alters permeability Topical
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Oxacillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking
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Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
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Para-aminosalicylic acid Antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Secondary TB drug
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Penbutolol Sympatholytic adrenergic antagonist Antihypertensive Bronchoconstrictor
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Penicillins lactam antibiotics Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan
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Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Acid labile Inhibits peptidoglycan cross-linking
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Penicillin V Penicillin antibiotic Cell wall synthesis inhibitor More acid resistant than Penicillin G Inhibits peptidoglycan cross-linking
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Phenylephrine Sympathomimetic 1 adrenergic agonist Vasoconstrictor Nasal decongestant
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Phenylpropanolamine Indirect sympathomimetic Nasal decongestant Removed from market* (may be in medicine cabinets!)
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Physostigmine Anticholinesterase Bradycardic Vasodilator Bronchoconstrictor
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Pilocarpine Cholinomimetic Muscarinic agonist Antiglaucoma Bronchoconstrictor
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Pindolol Sympatholytic adrenergic antagonist Antihypertensive Bronchoconstrictor
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Piperacillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
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Pirbuterol Sympathomimetic 2 adrenergic agonist Bronchodilator
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Polymyxin B Antibiotic Disrupts gram negative cell membrane Binds phosphatidylethanolamine Bactericidal
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Prednisone Adrenocorticosteroid Glucocorticoid Antineoplastic Anti-inflammatory Not by inhalation
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Probenecid Uricosuric Adjunct in penicillin therapy
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Procaine Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Repository preparation Inhibits peptidoglycan cross-linking
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Promethazine Classical antihistamine Antipsychotic Antiemetic H 1 antagonist
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Propranolol Sympatholytic adrenergic antagonist Class II antiarrhythmic Antihypertensive Bronchoconstrictor
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Pseudoephedrine Sympathomimetic and adrenergic agonist Vasoconstrictor Nasal decongestant
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Pyrazinamide Antibiotic Major drug for tuberculosis
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Pyridostigmine Anticholinesterase Vasodilator Treatment for myaesthenia gravis Bronchoconstrictor
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Quinopristin/Dalfopristin Streptogramin antibiotic Protein synthesis inhibitor 50S ribosomal subunit
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Rifampin Antibiotic Nucleic acid synthesis inhibitor Inhibits DNA dependent RNA polymerase Major drug for TB
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Ritonavir Antiretroviral Protease inhibitor (PI)
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Salmeterol Sympathomimetic 2 adrenergic agonist Long acting bronchodilator
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Saquinavir Antiretroviral Protease inhibitor (PI)
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Silver sulfadiazine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical
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Spectinomycin Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome
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Streptomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Succinylcholine Paralytic Depolarizing blocker Paralyzes skeletal muscles Bronchoconstrictor
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Sulfacetamide Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical
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Sulfadoxine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Dihydropteroate synthetase inhibitor
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Sulfamethoxazole Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase
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Sulfisoxazole Sulfonamide antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase
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Sulfonamides Antibiotics Nucleic acid and protein synthesis inhibitors Inhibit dihydropteroate synthetase
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Terbinafine Allylamine antifungal Inhibits ergosterol synthesis by inhibiting squalene epoxidase
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Terbutaline Sympathomimetic 2 adrenergic agonist Short acting bronchodilator Tocolytic Uterine relaxant
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Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment
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Theophylline Bronchodilator Methylxanthine Phosphodiesterase inhibitor Used in asthma
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Ticarcillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
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Timolol Sympatholytic adrenergic antagonist Antihypertensive Glaucoma treatment Anti-anginal Bronchoconstrictor
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Tobramycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Triamcinolone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled
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Trimethoprim Antibiotic Protein and nucleic acid synthesis inhibitor Folic acid antagonist Inhibits bacterial dihydrofolate reductase
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Tripelennamine Classical antihistamine H 1 antagonist
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Vancomycin Antibiotic Inhibits cell wall synthesis Not a lactam
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Voriconazole Triazole antifungal Inhibits synthesis of ergosterol by inhibiting lanosterol 14 demethylase
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Zafirlukast Leukotriene inhibitor LTR 1 and LTD 4 antagonist Asthma treatment
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Zalcitabine Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI) Dideoxycytidine (ddC)
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Zidovudine Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI) Azidothymidine (AZT)
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Zileuton Leukotriene inhibitor 5-lipoxygenase inhibitor Used in asthma
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