1. Swiss Life Sciences Trend Analysis 2015

2. About Us The following statistical information has been obtained from Biotechgate. Biotechgate is a global, comprehensive, Life Sciences database encompassing the Biotechnology, Pharmaceutical and Medical Device industries. www.biotechgate.comwww.biotechgate.com The Swiss Life Sciences Database is a part of the global Biotechgate and is brought to you in partnership with the Swiss Biotech Association, BaselArea and Life Sciences Zurich / Canton of Zurich. www.swisslifesciences.com www.swisslifesciences.com Biotechgate is owned and operated by Venture Valuation AG, a Zurich based company specializing in independent assessment and valuation of technology-driven companies in high growth industries, such as the Life Sciences (Biotech, Pharma, Medtech), ICT, high-tech, Nanotech, Cleantech and Renewable energy. www.venturevaluation.comwww.venturevaluation.com

3. Overview of the Swiss Life Science Industry 2015 Statistics Total Biotech Companies343 Medtech companies231 Pharma companies47 Investor companies40 Public / Non-Profit Organizations / Medical Facilities194 Other life science related companies888 Percentage of Publicly Owned Companies4% Biotech Venture financing 2013 / 2014USD 196m / USD 321m Life Sciences Venture Financing 2013 / 2014USD 267 m / USD 420m Number of Technologies205 Licensing Opportunities136

4. Number of Employees

5. Company Ownership

6. Overview of the Swiss Biotechnology Industry 2014 Statistics2015 Statistics 346Total Biotech Companies343 101Biotech - Therapeutics100 172Biotech - R&D Services171 73Biotech - Other72 94%Percentage of SME's89% 4%Percentage of Publicly Owned Companies4% USD 325m (2013)Venture Financing/Capital RaisedUSD 321m (2014) 100Licensing Opportunities136

7. Company Foundation Timeline

8. Key Activities of Biotechnology Companies

9. Biotech Products - Breakdown by Indication

10. Products in the Pipeline – 4 years report

11. Biotechnology Financing in Switzerland – 5 year report * Until May 2015

12. Major Biotech Financing Rounds (H2 2014 – H1* 2015) CompanySectorUSD M Molecular Partners AG Biotech – Therapeutics & Diagnostics97.4 Biocartis SABiotechnology - R&D Services78.7 CRISPR TherapeuticsBiotechnology - R&D Services64 Auris Medical AGBiotech – Therapeutics & Diagnostics56 * Until May 2015

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14. Terms of Use The “Swiss Life Sciences Trend Analysis” is based on data entered in the Biotechgate Database available at www.biotechgate.com. The statistics and graphs in this presentation are based on figures and information entered in this database and we do not guarantee any accuracy hereof. The use of the figures and graphs provided in this report is free of charge for any presentations as long as www.biotechgate.com is clearly cited as the source. For all other uses please contact us for terms and conditions. Biotechgate c/o Venture Valuation VV AG Kasernenstrasse 11 8004 Zurich Switzerland +41 (43) 321 86 60 www.venturevaluation.com