1. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc Socioeconomic position (SEP) and ageing Why do we age so differently? Merete Osler Research Centre for Prevention and Health & Insitute of Public Health, University of Copenhagen VELUX FONDEN Funded by:

2. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc Socioeconomic position (SEP) and ageing  Copenhagen-Odense  SEP and ageing- selection or causation  Copenhagen-Aarhus  SEP and molecular biomarkers

3. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc Socioeconomic position Health Familiar factors (genetics and rearing environment) Ageing (longevity, chronic disease, Disability) Twin register/-cohorts Metropolit 1953- male birth cohort

4. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc  Limitations in running 100 m  Dental status  General health  Fatigue The Metropolit cohort 6,292 men born in 1953 in Copenhagen who participated in a follow-up survey in 2004 Middle-aged Danish Twins (the MADT study) 2,198 male twins born 1931-1952 who participated in a health survey in 1995.

5. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc

6. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc Metropolit MADT OR Per unit decrease Limited in running Childhood SEP 1.03 (1.00-1.08) 1.08 (1.00-1.17) Adult SEP 1.61 (1.49-1.73) 1.24 (1.16-1.36) Poor dental status Childhood SEP 1.25 (1.08-1.43) 1.06 (0.98-1.10) Adult SEP 3.06 (2.24-4.09) 1.37 (0.96-1.30) Poor self-rated health Childhood SEP 1.07 (1.01-1.15) 1.12 (0.96-1.28) Adult SEP 1.66 (1.48-1.86) 1.12 (1.00-1.10) Fatigue Childhood SEP 1.10 (1.04-1.17) 1.03 (0.95-1.12) Adult SEP 1.47 (1.32-1.62) 1.18 (1.09-1.23)

7. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc

8. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc Socioeconomic position Familiar factors (genetics and rearing environment) Ageing (longevity, chronic disease) Twin register- linked to health and social registers in Statistics Denmark Mia Madsen’ PhD-study

9. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc Socioeconomic position Molecular biomarker (telomer length, mitochondrial expression) Subsample of the Metropolit cohort examined CAMB high and low adult SEP Laila Bendix’- post-doc study

10. - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc Socioeconomic position Familiar factors (genetics and rearing environment) Ageing (longevity, chronic disease) Sibling cohort study- linking family database-to health and social registers in Statistics Denmark New PhD-study/post doc? Social status and telomeres in a longitudinal design