1. THE BEAN LAB: ALLELE FREQUENCY

2. THE BEAN ALLELE FREQUENCY LAB Purpose: The following pictures are a guide to show one example of how the allele frequency could change in a population due to a genetic disorder. Setup: The three types of beans (red [RR], pinto [Rr] and white [rr]) will be used to represent a population of individuals with a certain trait. If an individual has the recessive phenotype (rr) then there is a 50% chance of surviving to reproduce. Being a carrier of the trait (Rr) has no bearing on mortality. The 2012-13 class has gone through the lab and developed a set of instructions to go along with the following pictures to help walk you through how to do the lab.

3. White, rr (16) Red, RR (16) Pinto, Rr (32) Slide #1 R and r frequency = 16 + 16 + 32 64 +64

4. White, rr (8) Red, RR (16) Pinto, Rr (32) Slide #2

5. The Dating Game Slide #3

6. Who got married to who from this Parent Generation (P) Slide #4

7. The offspring of those couple, now known as the First Generation (F1). Slide #5

8. How did we get these numbers of beans?

10. Red, RR (37)Pinto, Rr (54)White, rr (21) Slide #6

11. Red, RR (37)Pinto, Rr (54)White, rr (11) Slide #7

12. Slide #8

13. Slide #9

14. Slide #10

15. Slide #11 Red, RR (82)Pinto, Rr (92) White, rr (30)

16. Slide #12 Red, RR (82)Pinto, Rr (92) White, rr (15)

17. Slide #13

18. Slide #14

19. Slide #15

20. Slide #16 Red, RR (172)Pinto, Rr (166) White, rr (38)

21. IF WE CONTINUED ON THIS PATH, WHAT SHOULD THE NEXT SLIDE SHOW?

22. Slide #17 Red, RR (172)Pinto, Rr (166) White, rr (19)

23. DATA ANALYSIS

26. What is happening to the overall bean population? Why is this happening to the OVERALL bean population? Could we expect this pattern to continue indefinitely? What factors could stop this pattern?

29. OTHER QUESTIONS ON BEAN EVOLUTION * Will the white beans ever completely disappear at this rate? * What are some scenarios that could happen to cause the white beans to completely disappear? * The mechanism of evolution that this lab demonstrates is ______ because of ________.

30. OTHER MECHANISMS THAT COULD AFFECT ALLELE FREQUENCY

31. MIGRATION (GENE FLOW) Original Population New First Generation Reproduction Populations

32. MATE SELECTION Original Parent Pairs New Parent Pairs

33. SMALL POPULATION + CHANCE EVENT – DANGEROUS MUTATION Original Population Reproduction Population

34. INTRODUCTION OF A PREDATOR Original Population Fire Breathing Dragon who eats red beans for lunch