1. by Dr. Adrienne Hicks

2.  Cardiology  Pulmonology  Renal  Gastrointestinal  Endocrine  Reproductive  Neurology  Musculoskeletal  Psychiatry  Pediatrics  Surgery  Emergency  Hematology  Oncology  Biochemistry  Genetics  Microbiology  Immunology

3.  Hypothalamus-Pituitary Axis  Male/Female Reproduction  Menstrual Cycle  Adrenal Gland Function/Disorders  Thyroid Gland Function/Disorders  Growth Hormone Function/Disorders  Prolactinoma  Diabetes Mellitus  Diabetes Insipidus

4. There are 2 types of Diabetes Insipidus:  Neurogenic Diabetes Insipidus  Nephrogenic Diabetes Insipidus

5.  Caused by the brain trauma or injury  Hypothalamus not producing Antidiuretic Hormone (ADH), also known at Vasopressin, to be secreted to and released from the Posterior Pituitary Gland in the brain  Body in a dehydrated state where the kidneys cannot reabsorb water and urinate large volumes of dilute urine

6.  Caused by kidney damage or injury  The Antidiuretic receptors in the convoluted ducts of the kidney are not responding the Antidiuretic Hormone (ADH)  Body in a dehydrated state where the kidneys cannot reabsorb water and urinate large volumes of dilute urine

7. Water Deprivation Test:  Do not allow patients to drink fluids for 4-18 hours.  Administer Desmopressin (a derivative of Vasopressin)  Monitor blood and urine osmolarity  If patients begin to concentrate their urine, they have Neurogenic Diabetes Insipidus  If patients still cannot concentrate their urine, they have Nephrogenic Diabetes Insipidus

8. Neurogenic Diabetes Insipidus  Desmopressin- give patient what is missing from body Nephrogenic Diabetes Insipidus  Thiazide Diuretics – correct hypernatremic state of dehydration  Plenty of fluids