1. Constant Dosage day 7 Apigenin Control

2. Weight Adjusted Dosage Control Apigenin

3. Combined Mean Bone Volume Ave BV [mm 3 ]St Dev BV [mm 3 ] Apigenin0.01040.014307201 Control2.11173.134714543

4. Student t-Test Apigenin vs. Control t-Test: Two-Sample Assuming Equal Variances ApigeninControl Mean0.01042.1117 Variance0.0002046969.826435 Observations66 Pooled Variance4.91331998 Hypothesized Mean Difference0 df10 t Stat-1.641954672 P(T<=t) one-tail0.065815656 t Critical one-tail1.812461102 P(T<=t) two-tail0.131631311 t Critical two-tail2.228138842

5. Student t-Test Apigenin vs Control Constant dosage t-Test: Two-Sample Assuming Equal Variances Variable 1Variable 2 Mean0.0073673.908633 Variance4.1E-0514.80619 Observations33 Pooled Variance7.403115 Hypothesized Mean Difference0 df4 t Stat-1.75608 P(T<=t) one-tail0.07696 t Critical one-tail2.131847 P(T<=t) two-tail0.15392 t Critical two-tail2.776445

6. Student t-Test Apigenin vs Control Weight Adjusted t-Test: Two-Sample Assuming Equal Variances Weight Adjusted Variable 1Variable 2 Mean0.0134330.314767 Variance0.0004430.072991 Observations33 Pooled Variance0.036717 Hypothesized Mean Difference0 df4 t Stat-1.92601 P(T<=t) one-tail0.063197 t Critical one-tail2.131847 P(T<=t) two-tail0.126395 t Critical two-tail2.776445