1. Drug Testing in the U.S. Racing Industry Scot Waterman, DVM Executive Director RMTC

2. Drug Testing Statistics Results from two surveys sent in 2001 by the NTRA and 2008 by the RMTC Results from two surveys sent in 2001 by the NTRA and 2008 by the RMTC Surveys were substantially similar and very detailed Surveys were substantially similar and very detailed Able to draw conclusions as to how drug testing is changing Able to draw conclusions as to how drug testing is changing Some statistics will be presented without identifying jurisdiction Some statistics will be presented without identifying jurisdiction

3. Animal Selection for Testing “Top 12” Avg Tested Per Card Avg Tested Per Race #1 36 (TB) 33 (H) 4.0(TB) 3.0 (H) #2242.0 #3232.4 #4222.2 #5202.0

4. Total Spent Annually on Lab Services (2007) “Haves” “Have Nots” #1 $4.0 million #38 $10,000 #2 $3.4 million #37 $15,000 #3 $3.4 million #36 $26,000 #4 $2.0 million #35 $50,000 #5 $1.7 million #34 $52,000

5. Treatment of Laboratory Fees

6. Sample Collection Medium of Choice

7. Urine Screening Techniques 2001 vs. 2007 Methodology Number of States Utilizing—2001 Number of States Utilizing—2007 Thin Layer Chromatography 28/30 (93%) 19/28 (63%) ELISA 30/30 (100%) 18/18 (100%) HPLC 11/30 (37%) 22/27 (84%) GC/MS 11/30 (37%) 16/27 (59%) LC/MS 5/30 (17%) 12/25 (48%)

8. Number of ELISA by State

9. MS Equipment Cross-Section Sample Lab/Jurisdiction # LC/MS # GC/MS California106 Pennsylvania81 Florida32 Ohio22 Illinois14 New Jersey 14 Massachusetts01 Maine03

10. Jurisdictions Utilizing Accredited Labs in 2007 Jurisdiction Accrediting Agency & Standards Arkansas A2LA, ISO 17025 (Industrial) Arizona California A2LA, ISO 17025 (UC-Davis) Colorado A2LA, ISO 17025 (Industrial) Florida NSFTC, ISO 17025 (Univ. of FL) Kansas A2LA, ISO 17025 (CFTS) North Dakota A2LA, ISO 17025 (Industrial) Pennsylvania A2LA, ISO 17025 (Univ. of PA) South Dakota A2LA, ISO 17025 (CFTS)

11. Aggregate Statistics 2001 Total 2001 into 2007 dollars (inflation adjusted) 2007 Total Total Approx Annual Testing Spending (Responding Jurisdiction) $24 million $28,185,336 $28 million Average Spend per Responding Jurisdiction $814,000$955,953$836,000

12. RMTC Drug Testing Initiatives Post-race testing in the United States: Post-race testing in the United States: –Currently 18 laboratories conducting testing in US…too many labs chasing too few dollars –Only 5 labs ISO 17025 accredited –Funding is state-by-state and many times is under state procurement laws which reward low bidder or is statutorily directed –No industry standards for US testing labs

13. RMTC Drug Testing Initiatives 1. Creation of Industry Standards for Labs: –Starting point is Lab Standards document created by the World Anti-Doping Association –WADA labs must be ISO 17025 accredited –WADA conducts an external proficiency program with severe consequences for failure –WADA mandates that laboratories spend a percentage of their annual budget on research –WADA stick…Olympic Games, Horse Racing stick…????? Funding also a key issue

14. RMTC Drug Testing Initiatives 2. Post-doctoral and graduate student recruitment: –Our Laboratory Directors are aging…who replaces them? –Those with research programs that are racing related could do more with capable students –Developing a comprehensive program to target individuals with pharmacology/veterinary backgrounds to place in research positions and will also utilize racing laboratories and possibly U of A RTIP for broad racing education –Initial cost $100,000-200,000

15. RMTC Drug Testing Initiatives 3. Business Plan for US Drug Testing Infrastructure: –What is the most efficient system? –The Jockey Club has been tasked with this project 4. Sample Collection and Frozen Sample Strategies –Going back to McKinsey report on sample collection –Frozen sample program underway

16. RMTC Drug Testing Initiatives Pleased with progress in a short period Pleased with progress in a short period Will need broad industry support to implement Will need broad industry support to implement –Incremental funding will be needed –Industry needs to support commissions at legislative level Will need industry organizations with sticks to use them Will need industry organizations with sticks to use them

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