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Breast Conservation Surgery
DR Shailesh Puntambekar KEM Hospital Pune These Power Point presentations are free to download only for academic purposes, with due acknowledgements to authors and this website.
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BREAST CONSERVATIVE THERAPY
Dr Shailesh Puntambekar Consulting onco surgeon Associate professor , department of surgery, KEM Hospital, Pune, India
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In the good old days we made a clean breast of malignant disease
In the good old days we made a clean breast of malignant disease.In the modern era there is no TIT for T(h)AT
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HISTORY Halstead radical mastectomy Extended radical mastectomy
Modified radical mastectomy Breast conservation therapy
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BCS:Why? Ca Breast is a local manifestation of a systemic disease.Local radicality does not change survival Cosmetic Considerations Preservation of the nipple ,an important sensate focus
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Mastectomy is a socially devastating surgery for the downtrodden Indian woman and signals an end to her married life.The relevance of BCS in the Indian scene cannot be overemphasised.
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INDICATIONS Stage I & II ? Stage III
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CONTRAINDICATIONS Pregnancy Multicentric disease
Diffuse indeterminate micro-calcification Previous RT Large tumour/ breast ratio Collagen vascular disease Large breast size Central tumour
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Small Breast Realities
In a small breast not much to achieve in cosmesis Recurrence comes as Cancer en Cuirasse
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POST MRM NO RADIOTHERAPY
SATELLITE NODULES OVER THE CHEST WALL NO TREATMENT IS EFFECTIVE PALIATIVE INTENT OF RADIOTHERAPY
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Large Breast Realities
In a large breast recurrences not easily diagnosed A recurrence is viewed as a second primary
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SPECIAL CONSIDERATIONS
Family history Primary tumour histology Margin evaluation Extensive intraductal component
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METHODS Lumpectomy +Axillary dissection +RT Lumpectomy+SLN biopsy +RT
QUART- Quadrantectomy +Axillary dissection +RT CTART- Chemotherapy +RT
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Axillary Dissection Better control of locoregional recurrence
Accurate staging of disease To decide adjuvant therapy Prognosis
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GUIDELINES OF SURGERY Incision Technique Closure Axillary Dissection
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NEW INVESTIGATION MODALITIES
MRI Intra-op ultra-sound Touch preparation cytology Percutaneous needle biopsy
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NEW TECHNIQUES OF TUMOUR MANAGEMENT
Radio Frequency Ablation –RFA Cryosurgery Focused Ultrasound Percutaneous tumour extraction
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ROLE OF NEOADJUVANT Induction chemotherapy Drugs
Selection and monitoring of induction chemotherapy patients
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SEQUENCING OF CHEMOTHERAPY AND RT
6 Cycles of CMF followed by RT RT followed by 6 cycles of CMF 3 Cycles of CMF followed by RT followed by 3 cycles of CMF (sandwich therapy)
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RADIOTHERAPY IN BCT Intraoperative radiotherapy
Post operative radiotherapy Brachytherapy
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SPECIAL CASES Hereditory breast cancer Macromastia
Occult breast cancer Pregnancy Bilateral breast cancer
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BCS : Procedures Lumpectomy with 2 cm clearance
Lumpectomy with Axillary Dissection Quadrantectomy with Axillary Dissection
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Indications for BCS Small/Early Tumors in premenopausal women
Lateral than medial tumors More important to know the contraindications
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Contraindications for BCS
Very small Breast Very large Breast Advanced / High Grade Disease Lactating Breast Multicentricity Disease in opposite Breast
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RESULTS BCT / MRM T1 & T2 TUMOUR CONTROL RATE
5 YR RELAPSE FREE SURVIVAL RECURRANCE ONLY CONS SURGERY CONS SURGERY + RT 80 TO 90 % 70 TO 88 % 15 TO 40 % 2 TO 10 %
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Newer Frontiers Laparoscopic Axillary Dissection
Laparoscopic Int Mammary Clearance Technically feasible Clearance equal to standard technique Acceptability only after it stands the test of time
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Thank You
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