1. Arsenic “Because of its sinister, homicidal uses, arsenic became world-renowned as the ‘inheritance powder,’” “What made arsenic such a good homicidal poison is the same thing that makes it dangerous in environmental exposures — it gives no warning”.

2. Arsenic occurs naturally Drinking water Industrial by-products – Smelting – Coal Emissions Treated wood Pesticides or herbicides Food – Juices, Rice, Seafood

3. Forms of Arsenic Most common and stable – Arsenite (+3) – Arsenate (+5) Can bind to other elements to form inorganic/organic As. – Readily binds to Sulfur.

4. Why do we care? 20th most abundant metal in the Earth’s crust A known multiple organ carcinogen Non-cancer endpoints

5. Health Effects

6. Reproductive Effects Known developmental toxicant and teratogen. Readily crosses the placenta

7. Smedley, Pauline L.. 2008 Sources and distribution of arsenic in groundwater and aquifers. In: Appelo, Tony, (ed.) Arsenic in Groundwater : a World Problem. British Geological Survey Arsenic: continues to poison the water of millions around the globe

8. As contamination around the world