1. Blood

2. The different components of blood

3. RBC’s/Erythrocytes Transports O2 (on hemoglobin) Transports CO2 (on hemoglobin)

4. LEUKOCYTE FUNCTION: SEE TALBE 21.3—GREAT FUNCTION SUMMARY

5. Leukocytes Functions

6. Lymphocyte Basophil Neutrophil eosinophil Monocyte Leukocytes—WBC’s Granulocytes: have granules in cytoplasm Agranulocytes: no granules in cytoplasm

7. Neutrophils Function Phagocytize pathogens –particularly bacteria Structure/ID Multilobed (3-5) nucleus Inconspicuous granules ~2x size of rbc

8. Eosinophil Function Kills/attacks parasites Phagocytize allergens and antigen antibody complexes –reduces inflammation and allergic rxns Structure/ID ~ 2x size of rbc Very conspicuous red granules Bilobed nucleus

9. Basophil Function produces histamine and heparin –Promote inflamation: Structure/ID ~2x size of rbc Bilobed nuclues Very conspicuous blue granules

10. Monocytes Function Leaves vessels and then phagocytizes microorganisms and debri Structure/ID ~ 3x size of RBC/largest WBC Lobed  kidney shaped nucleus No granules

11. lymphocyte Function Produces antibodies (specific immunity) Structure/ID Slightly larger then rbc Round Nucleus fills most of cell No granules

12. Comparing Leukocytes A D CB

13. Platelets Function Reduce blood loss Platelet plug/clotting Stucture/ID Cell fragments Small (much smaller then rbc), darkish

14. Relative Abundance of Leukocyes Never Let Monkeys Eat Bananas »Nuetrophils (most common wbc) »Lymphocytes »Monocytes »Eosinophils »Basophils (least common wbc)

15. Differential WBC count Because: there is a typical amount of each WBC Each WBC has a different function WBC respond to their specific challenges by increasing in number Counting the relative abundance of each WBC (differential WBC count) can help assess what a condition/problem is

16. Normal WBC Frequencies Blood CellNormal Value Neutophil52-62% Eosinophil1-3% BasophilLess then 1% Lymphocyte25-33% Monocyte3-9%