1. Curtis Nordstrom, M.S. MS-3/6 – Medical University of Sofia Sofia, Bulgaria

2. Depression

7. Structure of omega-3 fatty acids

10. HARVARD-MCLEAN PSYCHIATRIC HOSPITAL STUDY (1999)

11. Harvard-McLean Study (1999) 30 patients with severe bipolar disorder Double-blind, placebo-controlled study 10g Fish Oil vs. 10g Olive Oil 4 months of treatment 11/14 (fish oil) vs. 3/16 (olive oil) reported diminished depression Fish oil also associated with diminished decrease in manic-depressive episodes

12. TEHRAN UNIVERSITY – SWALLOWNEST COURT HOSPITAL, UK (2008)

13. English-Iranian Study (2008) 60 patients, each with 15 behavioral markers for depression Three treatment groups: 1) Prozac alone; 2) Fish oil alone; 3) Prozac plus Fish oil Two months treatment Prozac = 50% decrease Fish oil = 56% decrease Prozac plus Fish oil = 81% decrease

14. Criticisms American Journal of Clinical Nutrition (2006) reported analysis of 12 trials, stating “…the evidence available provides little support…” but calls for larger trials. British Journal of Nutrition (2007) found increased EPA and DHA in diet brought no “beneficial or harmful effects on mood in mild to moderate depression.”

15. U.S. National Institutes of Health

16. What are you looking at? We’re done. Thanks for your attention!