1. Osteoporosis Research Center The Burden of Osteoporosis Estimates are that by the year 2020, one in two Americans will have or be at high risk for osteoporosis. Surgeon General’s Report, 2004

2. Osteoporosis Research Center Why participate in osteoporosis research?

3. Osteoporosis Research Center Benefits of research For Society and future generations: Better scientific understanding of bone health and osteoporosis More specific guidelines on preventing osteoporosis Increased treatment options Fewer persons living with the burden of osteoporosis Decreased cost to society

4. Osteoporosis Research Center Scientific Contributions made by the Creighton Osteoporosis Research Center Menopause is associated with bone loss Menopausal bone loss starts about 2 years before the last menstrual period and on average leads to loss of about 6- 12% of the skeleton Calcium supplements are effective in decreasing bone loss Calcium supplements are much better absorbed if taken with food Average daily requirements for calcium Importance of vitamin D in bone health Safety and efficacy of all of the new medications for osteoporosis

5. Osteoporosis Research Center For the individual participant: Determination of whether the participant has osteoporosis or is at high risk for it (Free bone density testing) Physical examination and laboratory tests (vary depending on the protocol) Education about bone health and osteoporosis Free medication Free calcium and vitamin D supplements Close monitoring of the response to treatment Much oversight to assure safety of the participant Help with adhering to the regimen Monetary stipend often included Benefits of research

6. Osteoporosis Research Center

7. Creighton Osteoporosis Research Center Contact Information http://osteoporosis.creighton.edu 280-BONE (2663) 1-800-368-5097