1. Stop Smoking With Hypnotherapy Study A Proposal

2. Bupropion studies 615 smokers – randomised to drug 100mg, 150mg, 300mg or placebo for 7 weeks Try to stop at 1 week For 300 mg - at 7 weeks[course end] –10.5% stop with placebo –24.4% stop with drug At one year point prevalence [ no smoking for last week] –12.4% placebo –23.1% drug

3. Bupropion studies 893 smokers one of 4 treatments for 9 weeks – 12 month point prevalence –Placebo oral + placebo patch  15.6% –Bupropion 300mg + placebo patch  30.3% –Nicotine patch + oral placebo  16.4% –Bupropion 300mg + nicotine patch  35.5%

4. Bupropion studies Continuous absence rates = –Bupropion alone  18.4% –Bupropion +patch  22.5% Cost –£86 + counselling – 5 sessions

5. Bupropion studies Problems with Bupropion –11% dry mouth –42% insomnia –6% hypertension { if given with patch} –1:1000 - fitting

6. Bupropion studies Contraindications –Epilepsy –Pregnancy –History of fits –History of head injury –Diabetes on drugs or insulin –Patients on TheophyllineSystemic steroids Antipsychotics Antidepressants

7. Hypnotherapy Studies Hypnotherapy –Safe –Specific Difficult to generalise Few published single session studies

8. Hypnotherapy Studies 226 Smokers [ Spiegel Frishholz Spiegel] –Single session treatment –2 year follow up 53% stop at one week 23% stop at two years

9. Hypnotherapy Studies 40 patients [Berkowitz Townsend Kohberger] –Single session 25% stop at 6/12

10. Hypnotherapy Studies LCCH method Single sessions Cost £ 150 approx Easily learned No side effects Does it work ??

11. Hypnotherapy Studies LCCH study –Single hypnotherapist –LCCH method One hour session only –Follow up one month to one year –Postal Questionnaire

15. LCCH Study Results 59 questionnaires sent { follow up 1/12 to 1 yr } –35 Returned 59.3% Of those returned –30 stopped 85% –1 cut down 2.8% –4 continued unchanged 11..4% At one month –23 stay stopped 65.7%

16. LCCH Study Results Results beyond this unsatisfactory due to lack of follow up BUT no known restarters after 6 months –Restarters 3 at less than one month 4 at 1-3/12 2 at 4-6/12 –We have a definite 12 stopped at one year { 34% } but as data is incomplete Could presume 21 stopped at one year which would be 60% stop at one year

17. LCCH Study Results

18. Hypnotherapy Proposal Randomised study - Possible Studies In conjunction with Community Stop Smoking Clinics Single session LCCH method hypnotherapy Vs Bupropion + counselling Possible arms –Single session hypnotherapy –Single session hypnotherapy + NRT –Single session hypnotherapy + Bupropion –Bupropion + counselling