1. Clinical Trials with SARC We’re here to help.

2. What can SARC do for you? Provide help developing a research idea Provide help with contacting pharma Provide help securing research funding – Identify granting agencies, foundations, etc – Assist in applying for funding Provide help writing a research protocol Provide help conducting a research study

3. What types of studies? Any study requiring more than 1 site – Small studies of rare disease subtypes requiring many sites for participation – Large studies of more common diseases – Pilot studies, correlative studies – Phase 1/1b studies

4. What is the process? Discuss an idea with a member of the SARC leadership Submit a Concept Sheet (available at sarctrials.org) Review by Concept Review Committee, then to Clinical Research Committee and/or Developmental Therapeutics Committee Written comments returned with suggests for change, discussion of next steps, etc

5. SARC is well-poised to conduct important sarcoma studies What are the major outstanding questions in sarcoma clinical research? In the next 6 months, let’s identify these topics and begin to design the relevant studies