Download presentation
Presentation is loading. Please wait.
Published byPhilomena Walsh Modified over 9 years ago
1
Pulse Electroporation System Onyx Medical Inc.
2
Various TDD Technologies Various TDD Technologies Electroporation - Using short electrical modulated pulses of high voltage to create transient aqueous pores in the skin. Iontophoresis – Using low voltage electrical current to drive charged drugs through the skin. Sonophoresis – Using ultrasound to disrupt the stratum corneum. Thermal energy – Using heat to make the skin more permeable Magnetophoresis - has been investigated as a means to increase drug flux across the skin. Needle Free Injection - devices for “firing” molecules through the skin at high velocity
3
Electroporation Non-invasive Alternative to mesotherapy Virtual mesotherapy or without needles Painless procedure Introduction of drugs alternating current rearrange the structure in the cells of the outer layer of skin Acts as a virtual syringe Changes direction (polarity) continuously slowly Generating new pores Micro and macromolecules 500,000 Dalton as collagen. 800.000 Dalton as hyaluronic acid
4
Electroporation For electroporation we need: Membrane potential: 0.5-1.5 volts Disrupt lipid layer Open biological channels (aquous) These channels stay open several seconds Change polarity constantly
5
When the pulse ceases, the membrane returns to its original structure, leaving retained product that has penetrated into the interior of the cell in place. The application of an electrical pulse momentarily disrupts the cell membrane, allowing entry of product. Background
6
Electroporation Electric doors called biological channels Electric pulse changes membrane polarity By slowly changing the polarization we do not cause electrolysis This disrupts lipid layer
7
Open Channels
8
Intercellular Communications
9
Cellular Penetration
10
Electroporation This effect lasts for seconds, therefore allowing the introduction of substances. Hydrofilic and hydrophobic molecules penetrate at the rate of 1 g every 1 - 1.5 minutes. Continuous formation and appearance of biological channels Dramatically increases skin permeability.
11
Conclusion Electroporation is a process that uses high-voltage current to make cell membranes permeable to allow the introduction of new materials. In a practical sense Electroporation is opening a door that allows us to insert “products” into the body.
12
Methodology Research documents 4 times better results when you do an exfoliation such as a peel or micromicrodermabrasion before Electroporation. This eliminates dead cells from the Keratinic layer. This changes the skin potential and makes it easier to create biological channels.
13
Comparison with Microdermabration
14
Indications Introduction of substances for: –Skin treatment –Cellulite –Flaccidity –Wrinkles –Obesity –Collagen production
15
Contraindicaciones Pacemakers, heart valves or other active implants. Epilepsy Pregnant women Immediately after Botox Skin outbreaks or on infected tissue Metal plates or other metal objects Ulcer or gastroenteritis
16
Wrinkles Instruction: Clean and dry skin the skin. Exfoliate by microdermabrasion. Optional: Use a micro roller after microderm. Select Protocol Power:70% - 80% Time of application: 20 – 25 minutes Amount of product: 4 to 6 cc, divided into face, neck, and décolleté Method: Circular motion, soft and slow until completely absorbed Frequency of session: One session a week during five to six weeks After one session every two week for one month A monthly session as maintenance
17
Decolette Instruction: Clean and dry skin the skin. Exfoliate by microdermabrasion. Optional: Use a micro roller after microderm. Select Protocol Power: 70% - 80% Time of application : 15 – 20 minutes Amount of product :4 cc Method: Circular motion, soft and slow until completely absorbed Frequency of session: One session a week during five to six weeks After one session every two week for one month A monthly session as maintenance
18
Body Firming Instruction: Clean and dry skin the skin. Exfoliate by microdermabrasion. Optional: Use a micro roller after microderm. Select Protocol Power: 80% - 90% Time of application: 15 – 20 minutes Amount of product: 5 to 6 cc (depending if we have to reduce or reaffirm) Method: Circular motion, soft and slow until completely absorbed Frequency of session: One session a week during six to eight weeks After one session every two week for one month A monthly session as maintenance
19
Breast Firming Instruction: Clean and dry skin the skin. Exfoliate by microdermabrasion or gentle enzyme peel. Select Protocol Power: 80% - 90% Time of application: 15 – 20 minutes Amount of product:3 - 4 cc Method: Circular motion, soft and slow until completely absorbed Frequency of session: One session a week during six to eight weeks After one session every two week for one month A monthly session as maintenance
20
Facial Rejuvenation Instruction: Clean and dry skin the skin. Exfoliate by microdermabrasion. Optional: Use a micro roller after microderm. Select Protocol Power: 70% + Face, 30-40% Lips Time of application: 20 – 25 minutes Amount of product: 5 to 6 cc, divided into face, neck, and chest (also hands) Method: Circular motion, soft and slow until absorbed Frequency of session: One session a week for three to four weeks After one session every two week for one month A monthly session as maintenance
21
Localized Obesity Instruction: Clean and dry skin the skin. Exfoliate by microdermabrasion. Optional: Use a micro roller after microderm. Select Protocol Power: 85% - 95% Time of application: 15 – 20 minutes Amount of product: 6cc - 10 cc Method: Circular motion, soft and slow until absorbed Frequency of session: One session a week during six to eight weeks After one session every two week for one month A monthly session as maintenance
22
Cellulite Instruction: Clean and dry skin the skin. Exfoliate by microdermabrasion. Optional: Use a micro roller after microderm. Select Protocol Power: 85% - 95% Time of application: 15 – 20 minutes Amount of product: 6 - 10 cc Method: Circular motion, soft and slow until absorbed Frequency of session: One session a week during six to eight weeks After one session every two week for one month A monthly session as maintenance
23
ELECTROPORATION ONYX MEDICAL INC. 1-800-333-5773WWW.ONYXMEDICAL.COM
Similar presentations
© 2024 SlidePlayer.com. Inc.
All rights reserved.