1. Scientific Board The Scientific Board is composed by some of the Tethis co- founder and by two scientists not directly involved in the firms activities. 5 co-founders members: 5 co-founders members: - Prof. Paolo Milani - Dott. Emanuele Barborini - Dott. Paolo Piseri - Dott. Andrea Ridi - Dott. Simone Vinati 2 external members: 2 external members: - Prof. Pier Giuseppe Pelicci, Director of the Experimental Oncology Dept., Europena Institue of Oncology, Milano Prof. Massimo Sancrotti, Analytical Division Leader, TASC-INFM National Laboratory, Trieste, Italy

2. Board of Directors The Board of directors is composed by six Tethis co-founders and one delegate from the University of Milano. Six co-founders members: Six co-founders members: - Dott. Stefano Morri - President - Dott. Andrea Ridi - CEO - Dott. Mario Zanone Poma - Prof. Paolo Milani - Ing. Giovanbattista Laghezza - Dott. Massimo Gatelli One delegate from the University of Milano: One delegate from the University of Milano: - Prof. Gianpiero Sironi

3. Production and deposition of thin films through cluster assembling on metallic, semi-conducting, polymeric and organic substrates Production and deposition of thin films through cluster assembling on metallic, semi-conducting, polymeric and organic substrates Compatible with traditional thin films deposition techniques, for the production of nano-composite materials Compatible with traditional thin films deposition techniques, for the production of nano-composite materials Compatible with microelectronics planar technologies Compatible with microelectronics planar technologies Parallel production processes with high deposition rate Parallel production processes with high deposition rate Production of micro and nanopatterned films with high spatial resolution and aspect ratio Production of micro and nanopatterned films with high spatial resolution and aspect ratio Main features of the technology

4. Fields of application Tethis technology provide an high versatility and has a very broad application spectrum, i.e.: nanostructured sensor arrays for gas sensing, electronic nose, multi-parametric sensors, environmental monitoring nanostructured sensor arrays for gas sensing, electronic nose, multi-parametric sensors, environmental monitoring supercapacitors supercapacitors fuel cells fuel cells photo-catalytic devices photo-catalytic devices lab on a chip for bio-technological applications (proteomics, genomics e post genomics) lab on a chip for bio-technological applications (proteomics, genomics e post genomics) bio-compatible materials for tissue engineering bio-compatible materials for tissue engineering

5. Technology (1) The production technique, called Supersonic Cluster Beams Deposition (SCBD), consists in the assembling of clusters produced in supersonic expansions. The cluster source, called Pulsed Microplasma Cluster Source (PMCS) was designed, developed, and patented by three co-founders of Tethis To Vacuum Pump PMCS Cluster Beam Nanostructured Thin Film Source Chamber Deposition Chamber

6. PMCS principle of operation Pulsed Valve CathodeAnodeNozzle Injection of an inert gas pulse Microplasma formation due to an intense electric discharge Ion sputtering of cathode surface Thermalization of the ablated material and cluster aggregation Expansion of the mixture gas-clusters into a supersonic cluster beam 12 34 Technology (2)

7. Pre-Industrial Deposition Apparatus (1) This apparatus is at the LGM Labs, University of Milano. It can be used by Tethis personnel due to an agreement between Tethis, INFM and the University of Milano

8. An example: Nanostructured composites materials for electrochemical applications Increase of Platinum content Platinum content: 1% at. Platinum content: 20% at.