1. “How To Design Your Model”

2. DOE Software
This EASY TO USE software has all the major experimental designs (general ANOVA, two-level full and fractional factorials, three-level factorials, several RSM designs, mixture designs, and much more).
More and more features are added with each new version of the software.
It has powerful graphical tools and it has been featured in several well-known texts on DOE. Apparently it has been WIDELY USED IN INDUSTRY.
The web site provides excellent DOE resources and one can download a 30-day full version from the web site.
Design of Experiment

3. DOE Wisdom
This software also claims that it offers PRACTICALITY and EASE-OF-USE that is IDEAL FOR BEGINNERS but with the computing power demanded by advanced users.
It basically offers VERY SIMILAR FEATURES TO DESIGN-EXPERT with the addition of the Pareto chart and a few other minor differences.
One can DOWNLOAD A 15-DAY FULL VERSION of the
software for the web site.
DOEpack
This standalone software available also FEATURES THE USUAL CLASSICAL AND TAGUCHI DESIGNS with a wide selection of SCREENING DESIGNS, PROCESS OPTIMIZATION DESIGN AND ANALYSIS TOOLS.
It has good graphical tools and an intuitive user interface

4. This standalone DOE software is developed by the well-known SAS Institute, developers of the SAS program.
This is also powerful software and provides design choices for almost every situation. Perhaps the additional feature that is not available in the other software is that the user can perform custom designs which give the experimenter the most flexibility.
Obviously, this feature is ONLY USEFUL FOR THE EXPERT USER. Limited time free download of the software is also available from the JMP web site.

5. Design Expert Version 7.1.5 or LATEST Version 8

6. Doe Vocabulary
Factor
One of the independent variables under investigation that can be set to desire value K
Number of factors or variables the effect of which are to be estimated in an experimental
Level
The numerical value or qualitative feature of a factor
Run
The act of operating the process with a factors at certain setting
Response
The numerical result of a run
Factor Experiment
Design to determine the effect of all possible combinations across all level of the factor under study
Factorial Factorial
Designed to examine k factors with the fraction of the runs required for a full factorial
Blocking
A strategy for designing experiment to provide the ability to eliminate from the experimental error a contributor of variability that is known but not under investigation

7. Why Goes For Experimental Design?1 2
EFFICIENCY Get more info from fewer experiments
FOCUSING Collect only info that really needed
is a useful complement to multivariate data analysis.
with designed experiments there is a better possibility of
testing the significance of the effects and the relevance
of the whole model .

8. Select Output Response
DOE Flowchart? 1 4 7
Set your objective
Select your design
Fit & Diagnose Model 5 8 2
Develop your strategy
Interpret Model
Select Input Factors
Will be explain next semester 9 6 3
Confirm
Model
Run Experiment
Select Output Response

9. Building a Experimental Design !
Your Final Year Project Titles
Example:
Studies Of Potential Parts Of Streblus asper (Kesinai) For Protease Production 1
To screen and identify the POTENTIAL PLANT PARTS of PROTEASE PRODUCTION from Streblus asper by using Design of Experiment (DOE).
DEFINE THE OBJECTIVE of the investigation: e.g. “sort out important variables” or “find the optimum conditions

10. Building a Experimental Design !3
Weight of your sample (g)
SELECT OUTPUT RESPONSE
that will be measured to describe the outcome of the experimental runs (response variables), and examine their precision 2
SELECT INPUT FACTORS
that will be controlled during the experiment (design variables), and their levels or ranges of variation.
Enzyme Activity (unit/mL)
Ratio (mol)
(Buffer : Sample)
Time of Extraction
(minutes)

11. Building a Experimental Design !4
SELECT YOUR DESIGN
CHOOSE among the available standard designs the one that is compatible with the objective, number of design variables and precision of measurements, and has a reasonable cost

12. Screening Design
The Screening designer supplies a list of popular screening designs for 2 or more factors.
Screening factors can be continuous or categorical with two or three levels.
The list of screening designs also includes designs that group the experimental runs into blocks of equal sizes where the size is a power of two.

13. 1
WELCOME!

14. START YOUR DESIGN!! 2

15. Choose
The Experimental
Design 3 4

16. in powers of two (4, 8, 16…) for up to 512 runs.
The choices appear in color on your screen. White squares symbolize full factorials requiring 2k runs for k (the number of factors) from 2 to 9.
The other choices are colored like a stoplight: GREEN FOR GO, YELLOW FOR PROCEED WITH CAUTION, and RED FOR STOP, which represent varying degrees of resolution: ≥ V, IV, and III, respectively.
This design builder offers full and fractional two‐level factorials for 2 to 21 factors
in powers of two (4, 8, 16…) for up to 512 runs.
For a quick overview of these color codes, press the screen tips button (or select Tips, Screen Tips) and click
topic 1: “What type of information do you want?”

17. Insert your factors and unit
Insert your range here!
Make sure the range is not too small or too big 8 7
Insert your factors and unit 9

18. Factors
Numeric
Temperature
Pressure
Categoric
Catalyst Type
Automotive Model

19. Choose number of response in your study10 11
Insert your response here! 12

20. Insert your experimental data here
Actual Values!!!! 14
Insert your experimental data here 13
List of experiment that you design before will be shown here 6 5
Run Experiment
Develop your strategy

21. 15
You might choose process factors in coded or actual

22. You’ve put in some work at this point so it is a good time to save it
You’ve put in some work at this point so it is a good time to save it. The quickest way of doing this is to press the standard save icon. But you can also go to the File menu and select Save As. Type in the name of your choice for your data file. Then click Save.

23. For Plackett Burman Design minimum factor is 11.
If your factors is less than 11, you add dummies factors to complete it.
Next step is the same as previous.

24. Response Surface Design
Response Surface Methodology (RSM) is an experimental technique invented to find the optimal response within the specified ranges of the factors.
These designs are capable of fitting a second order prediction equation for the response.
The quadratic terms in these equations model the curvature in the true response function. If a maximum or minimum exists inside the factor region, RSM can find it.
In industrial applications, RSM designs involve a small number of factors. This is because the required number of runs increases dramatically with the number of factors. The Response Surface designer in JMP lists well-known RSM designs for two to eight continuous factors. Some of these designs also allow blocking

25. CENTRAL COMPOSITE design, combines a two-level fractional factorial and two other kinds of points:
Fractional factorial point
Axial (or star) points, for which all but one factor set at zero (midrange) and one factor set at outer (axial) values.
Axial
Point
Centre
Point
Center points, for which all the factor values are at the zero (or midrange) value.
The BOX-BEHNKEN design, is an alternative to central composite designs.
One distinguishing feature of the Box-Behnken design is that there are ONLY THREE LEVELS PER FACTOR.
Another important difference between the two design types is that the BOX-BEHNKEN DESIGN HAS NO POINTS AT THE VERTICES OF THE CUBE defined by the ranges of the factors.
This is sometimes useful when it is desirable to avoid these points due to engineering considerations. The price of this characteristic is the higher uncertainty of prediction near the vertices compared to the Central Composite design.

26. Insert your optimize factor and your range here1
Insert your optimize factor and your range here
Number of run 2

27. Insert list of response involved in your optimization here3

28. Insert your experimental data here
Actual Values!!!! 5
Insert your experimental data here 4
List of experiment that you design before will be shown here 6 5
Run Experiment
Develop your strategy

29. Thank you…..