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Published byMagdalen O’Connor’ Modified over 9 years ago
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Hormones that Affect Blood Sugar
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Pancreatic Hormones Produced in the islets of Langerhans. –Beta (β) cells produce insulin. –Alpha (α) cells produce glucagon.
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Hormonal Response to High Blood Sugar ↑ blood sugar = release of insulin. Causes muscle, liver and other body cells to become permeable to glucose. Glucose stored as glycogen. Result = ↓ blood sugar.
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Hormonal Response to Low Blood Sugar ↓ blood sugar = release of glucagon. Promotes breakdown of glycogen into glucose, which is released into the blood. Result = ↑ blood sugar.
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Adrenal Glands Each composed of two glands. 1.Adrenal medulla short-term stress. 2.Adrenal cortex long-term stress.
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Adrenal Medulla Produces epinephrine (adrenaline) and norepinephrine (noradrenaline). “Fight-or Flight Response”. –↑ blood sugar (glycogen glucose). –↑ HR, breathing rate & cell metabolism. –Dilation of blood vessels. –Pupil dilation.
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Adrenal Cortex Produces 3 types of hormones: –Glucocorticoids. –Mineralcorticoids. –Sex hormones.
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Adrenal Cortex Glucocorticoids (e.g., cortisol): –Promotes conversion of amino acids to glucose –Promotes breakdown of fats to fatty acids –Decreased glucose uptake by muscles –Increased blood sugar in response to stress
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Fight or Flight and Blood Sugar Why block insulin during fight-or-flight response?
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Hormones that Affect Metabolism
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Two Major Glands Thyroid Gland Parathyroid Gland
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Thyroid Gland Thyroxine (T4) Triiodothyronine (T3) –Both need iodine to be produced. –Used to oxidize sugar and other nutrients. –More T4 in the blood will “boost metabolism”
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Hypothyroid or Hyperthyroid If the thyroid gland produces T4 and T3, hormones that regulate metabolism, what would happen if: a)The thyroid stopped producing T4 and T3? (hypothyroidism) b)The thyroid could not stop producing T4 and T3? (hyperthyroidism)
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Acronyms: TRH – Thyroid Releasing Hormone TSH – Thyroid Stimulating Hormone
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Parathyroid Glands Four groups of cells on the thyroid gland. Release a hormone called parathyroid hormone, or “PTH”. –PTH raises the calcium levels in the blood.
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Negative Feedback
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Calcitonin Calcitonin is also released by the thyroid, and it counter-acts parathyroid hormone (PTH) by: Inhibiting Ca 2+ absorption by the intestines Inhibits Ca 2+ reabsorption in the nephrons of the kidney
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Human Growth Hormone (HGH) Too much? - Giantism Too little? - Dwarfism Produced in and released from the anterior pituitary gland. Andre the giant 7 ft 4 inches 520 lb.
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Human Growth Hormone Cause cells to grow in size and in number. Promotes protein synthesis. Promotes the breakdown of fats. –↑ GH, muscles use fatty acids as energy –Loss of fat during growth spurts
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