1. { Nucleus The Brain of the Cell By: Bryonna Aldubayan

2.  Definition  Function  Significance  Structure and Components  Nuclear Envelope and Pores  Nucleolus  Nucleoplasm  Mitosis/Meiosis  Malfunctions/Disease Outline

3. In an atom: The nucleus is the center of an atom which contains the protons and neutrons Definition In a cell: The nucleus is the structure that contains the cell's genetic material (DNA) and controls the cell's activity in a eukaryotic cell.

4. Function The nucleus regulates all cell activity, growth and reproduction. It controls the cell through protein synthesis. Protein Synthesis is the process by which amino acids are arranged linearly into proteins through the involvement of ribosomal RNA, transfer RNA, messenger RNA, and various enzymes

5.  The nucleus contains DNA which contains coded instructions needed for cell reproduction and also produces proteins that control metabolism and other cell functions. Significance

6. Structure The nucleus is a spherical double membrane organelle. & Components The nucleus contains: Nuclear Envelope Pores Nucleolus Nucleoplasm

7.  The nuclear envelope is a double phospholipid bilayer membrane which surrounds the genetic material in eukaryotic cells.  Outer membrane  Inner membrane  The nuclear membrane is dotted with thousands of small holes called nuclear pores that allow material to diffuse in and out of the nucleus. Nuclear Envelope & Pores

8.  Small, dense region  Generally located in the center of the nucleus.  It is made of proteins and ribonucleic acids.  It is the location where the assembly of ribosomes begin. Nucleolus

9.  Highly Viscous Liquid  Enveloped by the inner membrane of the nuclear envelope.  Surrounds the chromatins and nucleolus Nucleoplasm

10. {{ Mitosis  Involves the replication of all eukaryotic cells except that of sex cells. Meiosis  Replication of only sex cells. Replication

11. {{ Mitosis  Cancer  Uncontrolled abnormal cell division  Spread through blood stream and lymph system  100 different types Meiosis  Down Syndrome  Trisomy 21 (nondisjunction)  Translocation  Mosaicism  3 different types Malfunctions

12. Cancer

13. Cancer

14. Down Syndrome Typical Cell Division

15. Down Syndrome Trisomy 21 (nondisjunction) Results in an embryo 3 copies of chromosome 21 Sperm or egg fails to separate

16. Down Syndrome Mosaic Chromosome 21 takes place in 1 initial cell division Mixture of 2 cell types

17. Down Syndrome

18.   "What Is Cancer?." - National Cancer Institute. N.p., 7 Mar. 2014. Web. 15 Mar. 2014..   "What Is Down Syndrome?." The National Advocate for People with Down Syndrome Since 1979. N.p., n.d. Web. 15 Mar. 2014..   "nucleus Images - Google Search." nucleus Images - Google Search. N.p., n.d. Web. 15 Mar. 2014.. Works Cited