1. Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease Transmission Advisory Committee (DTAC) Dr. Dan Kaul

2.  Current policy requires testing for living donor from areas endemic for Strongyloides, Chagas (T. cruzi), and West Nile Virus.  Living donor recovery hospitals are struggling with identification of risk factors and testing for these living donors. The Problem

3. #4- Promote Transplant Patient Safety Minimize risk to living organ donors Properly evaluate potential living donors #5- Promote Living Donor Safety Increase capacity to identify patient safety issues Strategic Plan

4. Provide guidance to members regarding the development of a protocol for identifying and testing potential living donors for seasonal and geographically endemic disease. Goal of the Proposal

5.  Highlights six “frequently” seen infections of this type based upon review of DTAC experience, existing literature and materials available on the CDC website  Format easily digestible for any member of transplant team using tables, maps, and text How the Proposal will Achieve its Goal

6. Product Guidance Document Target Population Impact: Living Donors (though it helpful to OPO staff as well) Total IT Implementation Hours 0/10,680 Total Overall Implementation Hours 20/17,885 Overall Project Impact

7.  Histoplasmosis  Coccidioidomycosis  Chagas (T. cruzi)  Strongyloides  Tuberculosis  West Nile Virus Specific Infections Included:

8.  Risk factors to consider  Who should be screened  How to screen  Management of infected living donor  Management of recipients  Infection avoidance between testing and transplant Guidance Includes:

9. RESOLVED, that the guidance document entitled “Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation,” as set forth in Exhibit C, is hereby approved, effective November 13, 2014. Resolution 16 (page 49)