1. 12-2 Chromosomes and DNA Replication Pg. 295

2. A. DNA and Chromosomes 1. Prokaryotes have no nucleus; contain a single, circular strand of DNA.

3. A. DNA and Chromosomes 2. Eukaryotes have 1000 times more DNA and it is more complicated.

4. A. DNA and Chromosomes 3. DNA Length – E.Coli Bacteria (large intestine) 4,639,221 Nitrogen Bases!! (1.6mm long)

5. A. DNA and Chromosomes 4. Chromosome Structure a. Nucleus of a human cell contains 1 meter of DNA! b. Human DNA binds with protein called histones to form chromatin.

6. B. DNA Replication 1. Replication is a copying process used by DNA to duplicate (copy) itself. 2. During DNA replication, the DNA molecule separates.

7. B. DNA Replication 3. Next, 2 new strands are made following the base pairing rules (A-T, C-G).

8. B. DNA Replication 4. Each original strand of the double helix serves as a template for the 2 new strands (Semi-Conservative).

9. B. DNA Replication 5. Many enzymes carry out replication (EX: Helicase unzips DNA) but the main enzyme is DNA Polymerase: – Joins nucleotides to make a DNA molecule – Proofreads DNA to correct mistakes animation

10. Replicate this DNA!!