1. 1 How Picsara can be used in Pathology. by

2. 2 Versatility Can be used in many disciplines Allows for MD co-operation Allows various HW to be connected.

3. 3 Examples of where Picsara is used: Dermatology Pathology & Other labs Ophthalmology Endoscopy Ultrasound Plastic Surgery

4. Picsara ◊ Digital image management ◊ Client and server ◊ Security ◊ High performance ◊ Multi user ◊ Analysis ◊ Integration with LIS & EPR 4

5. Some Customer references Karolinska University Hospital, Stockholm Sahlgrenska University Hospital, Gothenburg Sodersjukhuset, Stockholm St. Erik Eye Hospital, Stockholm Numerous regional Swedish Health Authorities Astra Zeneca Karolinska Institute, Stockholm NASA Volvo Aero Sandvik ABB Industries 5 HealthcareIndustry & Research

6. Picsara is extremely scalable 6 Single user From To (at various departments) (and/or LIS)

7. 7 Picsara vs PACS Picsara Derives from imaging outside radiology EPR/HIS/LIS centric, rather than RIS Specified by non- radiologists. Optimized client. Handles files not yet specified by DICOM Designed to handle multiple disciplines and departments in a hospital. Strong integration support, even non standard.

8. 8 Picsara integration Client in client OCX/HL7/API/ActiveX/COM Executable with switches (Direct access to database or non-standard solutions.) Server to server HL7/XML/DICOM or non-standard service solutions Picsara, full clientCase viewer

9. Security/ Departments One database-one hospital 9

10. Security/ Roles Different roles in different departments 10

11. Security/ Users Built in user management or connect to AD/external directory. 11

12. Security/ Audit trail and Statstics Who did what, when and were? How many images or documents are stored and where? 12

13. Security/ Forms Design forms for indivdual tasks or diciplines. No programming needed. 13

14. Analogue or digital video (DV). Live on-screen video. This is typically used in Endoscopy. Video as well as still images can be recorded and stored. Picsara’s capture feature allows for integration with the buttons on the handle to capture images or video. It can also be combined with a foot switch, if more buttons are needed.

15. High Resolution Direct-X cameras Fokus assistance Real time native control of camera, (without TWAIN)

16. Images, video, documents….. Picsara stores all kinds of files. Video can be edited and compressed to a preferred format.

17. Aperio solution 2D Barcode label Aperio Database AperioScan LIS Server Picsara server Slides are fed into the scanner by a lab assistant and the barcode is interpreted. All integration takes place in the background.

18. Aperio solution with Sympathy LIS, Workflow. Scenario 1 3 steps to review images

19. Enter ID number (barcode reader optional, Scan!) 1

20. Enter ID number 123-2007-251 FOTO Photo button is lit if there are images. Press! 2

21. Sympathy Picsara/ Aperio Two screen layout All slides open in a second, high resolution, window with one click or select individual slides + enter. 3

22. One screen and Picsara client. Different types of images. Scenario 2 123-2007-251 FOTO Search result

23. 123-2007-251 Image/session type FOTO Open sessions Open Select folders to open

24. 123-2007-251 Double click or drag to open FOTO

25. 123-2007-251 FOTO

26. Adding images with Macro stand, scenario 3 123-2007-251 Add picture

27. 123-2007-251 Picsara opens a new empty case. PAD, patient name etc. are automatically transfered from the LIS Add information If the camera has a live preview, It will show here automatically

28. 123-2007-251 Capture your images from your microscope or camera, analyse and sign. Capturing can be done with a foot switch, button on the microscope or by simple drag and drop

29. Additional features and examples 29/10 -All lenses can be calibrated for image analysis (one time event) -Calibration will automatically follow the image no matter where it is opened. -Each image is marked with the name and magnification of the lens (Free text) -An optional bar code reader attached to the microscope will read bar code labels (stickers) on each lens to automatically select the correct magnification and lens in Picsara on manual microscopes. -Each input device is named and will be stored with the image -All EXIF information (i.e. exposure date, type of camera, camera time etc) is saved and can be searched.

30. Collaboration 30 Due to Picsara’s ability to serve a whole hospital or trust, it’s easy to share images between various disciplines in a secure manner. An example would be Endoscopy and Pathology. It’s possible to set up rights for a Pathologist to for example only view images in the Endoscopy department and yet have full rights while in the Pathology department and vice versa. This can also be managed by the central HIS system. Pathology dept. Endoscopy dept.

31. Analysis 31/10 -In the basic version, simple area and length can be measured. Options: -The analysis module will give you more advanced features and measurements can be stored in the database and/or exported to Excel. Interactive measurements with your own Excel templates can be performed. - with the blob module you can threshold on light intensity (B/W analysis). -The script engine will let you run scripts built with the scrip builder. This is where the advanced user can build his own scripts involving colour analysis and other advanced features. The other users can then share the scripts by using the engine. -As a last step tailored analysis methods can be offered. Please contact your reseller for more info.

32. Macro or exterior photo 32/10 There are a number of cameras that can be used for Macro images in Picsara: - Canon SLRs like 20,30 or 40D can be connected directly to Picsara via a USB cable or wireless. This can be useful when doing autopsy for example. With the camera connected you can always be sure not to mix up images and memory cards. - A video/DV camera can be connected for recording various procedures for educational purposes. These films can be stored in a separate department or form to avoid being mixed up with clinical images. - A dedicated Macro stand with a HDV camera and foot controls for zoom and grabbing is also available. This gives a high resolution preview on the screen.