1. HORMONE BALANCE© Introduction, Class 1 of 5
Young Living Connect, LLC

2. HISTORY
1938: DES developed by Sir Charles Dodd, commonly prescribed during pregnancy to prevent miscarriages or premature deliveries
5-10 million exposed from 1938 – 1971
9 out of 10 daughters of women who took DES had deformed reproductive systems
50% would never conceive
One out of seven contracted a rare and often fatal cancer called adenocarcinoma; Also linked to rare form of testicular cancer in sons
1942: Premarin developed by Ayerst Laboratories
Put on market one year AFTER study published in Cancer Research
Reported: “Estrogen is a very important factor in cervical carcinogenesis.”

3. HISTORY
1970’s: Premarin considered gold standard for hormone replacement
1975: Clinical studies reported link between synthetic horse estrogen in Premarin and uterine cancers.
Wyeth-Ayerst required by FDA to put black-box warning on package inserts
Many believed it should have been pulled from the market!
*****Changed their tactics: Premarin (synthetic estrogen) + Progestin, also known as Provera (synthetic progesterone)
Called it PREMPRO

4. HISTORY
: NIH drug trial: Women’s Health Initiative, 16,608, y/o women participated
: Data and Safety Monitoring Board (DSMB) found no statistical problems and to continue the study
2001: National Cancer Institute and NIH: opinion dramatically contrasted above
2002: Abruptly ended study – found significant invasive breast cancers

5. HISTORY
2002: Journal of American Medical Association study published: 26% increase in breast cancers
2003: Women over 65 had increased risk of dementia or Alzheimer’s on Premarin
2004: Journal of the National Cancer Institute: 54% increased risk of ovarian cancer

6. HRT vs. BHRT Bio-Identical Hormones: The Keys that Fit
Receptor site for progesterone does not recognize estrogen or testosterone, only the molecular structure of progesterone; Bio-identical hormones are identical to human hormones, have 100% relative binding affinity (RBA)…no side effects. They fit perfectly unlike synthetic hormones.
Over 400 abstracts (studies) on safety and efficacy of BHRT

7. Your Endocrine System
Cholesterol: single building block molecule from which all hormones are derived; the body makes hormones from nutrients with the help of enzymes
Pituitary and hypothalamus: regulate flow of all hormones including estrogen, progesterone, and testosterone. Also directly interacts with neurotransmitters that regulate mood.

8. Your Endocrine System
Thyroid: (<97.8 hypothyroidism) produce TSH, T3, T4 and thyroid peroxidase, known for affecting weight
Adrenal glands: (<118 = adrenal fatigue) produce hormones and regulate sympathetic nervous system; secrete 3 hormones in response to stress: adrenaline, cortisol, DHEA (anti-aging hormone)

9. Sex Hormones Estrogen Develop female sex organs
Develop secondary sex characteristics
Maintain menstrual cycle
Support growth and function of uterus
Moisturize vagina and cervix
Stimulate cell growth

10. Sex Hormones Progesterone Progesterone
maintain uterus and prepare it for pregnancy
promote survival of egg once fertilized
stimulate bone building that can prevent or treat osteoporosis
act as natural diuretic
serve as natural antidepressant
Progesterone
foster calming effect on body
Maintain libido
promote regular sleep patterns
oppose estrogen’s predisposition to promote cell growth so as to provide protection against uterine, breast and ovarian cancer as well as fibrocystic disease

11. Sex Hormones Testosterone Testosterone Boost sex drive
Support feelings of arousal
Promote sense of well-being
Promote muscle strength and healthy body composition
Testosterone
Increase energy levels
Increase body hair production
Improve bone density
Produce enlargement of penis and testes, as well as the clitoris

12. HORMONES DHEA Body’s most abundant circulating hormone
DHEA production peaks by age 25
Drops dramatically each year thereafter
By age 70 most people’s DHEA levels have declined by over 80%, leading to hormonal imbalances that can affect quality of life
These kinds of imbalances also occur with other critical hormones in our aging bodies such as testosterone, estrogen, and progesterone

13. AGING Premenopause, mid 30’s Perimenopause, mid 40’s
Almost all women are estrogen dominant
DHEA drops 10% every decade after 30 years old
Decline correlated with degenerative changes such as heart disease, cancer and osteoporosis
Perimenopause, mid 40’s
Progesterone declines even more significantly while estrogen becomes sporadic with high peaks.
Testosterone drops
Decreased sex drive, energy, muscle tone,
Thinning of vaginal wall

14. AGING Post Menopause Menopause, late 40’s-50’s
Progesterone drops to almost zero
Some cases ovaries continue to produce significant amount of testosterone;
Some estrogen from adrenal glands and body fat
Frequently estrogen dominant which is risk for breast or uterine cancer
Hair loss, weight gain, wrinkly skin, urinary incontinence, low sex drive, heart disease and osteoporosis
Menopause, late 40’s-50’s
Hasn’t had cycle for at least 12 months
Not disease, just natural transition
Affects all sex hormones
Still continue to produce estrogen in ovaries
Adrenal glands and body fat perpetuating estrogen dominance

15. AGING Andropause Decline in testosterone, progesterone and DHEA
Increase in estrogen (estradiol)
Believed by late John Lee, MD to be primary cause of prostate enlargement and cancer

16. Vicious Cycle of Hormone Imbalance
Chronic stress
Adrenal produce adrenaline and cortisol…too much too long
Destroy healthy muscle and bone
Slows healing and normal cell regeneration
Impairs digestion
Dulls mental processes
Interferes with healthy endocrine function and weaken immune system
Gain abdominal fat
Body Fat
Body fat is bad for hormone balance
Conversely non balanced estrogen and progesterone predisposes you to gain weight.
Fat cells produce even more estrogen

17. Vicious Cycle of Hormone Imbalance
Synthetic hormone drugs
Phytoestrogen
Found to be potent anti-thyroid agents and add estrogen
Hormonal pollutants
Chlorine and fluoride in tap water ultimately raises estrogen
Birth control pills

18. Vicious Cycle of Hormone Imbalance
Phthalates: chemicals that soften plastic
Toxic to reproductive system
Found in toys
New shower curtain smell
Medical supplies (IV tubes and bags)
Plastic food wrapping
Fragrances
Scented candles
Phthalates
Air fresheners
Fabric softeners
Perfumes
Nail polish
Soft plastics our food is wrapped in (frozen pizzas)
Plastic water bottles

19. Vicious Cycle of Hormone Imbalance
Xenoestrogens “foreign”
Endocrine Disruptor Chemicals
Estrogen Mimicking Molecules
Pesticides
Herbicides
Plastics
Fuels
Car exhausts
Drugs
Hygiene products
Room deodorizers
Meats
Dairy products.
Affects reproductive, cognitive, thyroid, metabolism, digestion, hormone balance
Gender bent fish and frogs; known for 10 year; sperm count decreased by 50%
Fibroid cysts, cancer – Xenoestrogens cause cells to duplicate quickly
Heart disease – causes arteriosclerosis (hardening)
Past 60 years of chemicals; hormonal pollutants, steroids excreted by humans using HRT, birth control, agricultural run off, plastics, pesticides

20. ESTROGEN DOMINANCE
Estrogen promotes cell proliferation…Progesterone inhibits cell proliferation!
Increases risk of chronic diseases including cancer, cardiac disease, stroke and Alzheimer’s
Breast cancer patients show higher estrogen levels than those without breast cancer
Creates abdominal weight gain…fat cells produce even more estrogen
Linked to migraine headaches, anxiety disorders, insomnia and decreased mental acuity
No woman with or without a uterus or ovaries should ever take estrogen of any kind alone!

21. PROGESTERONE…to the rescue
Research: Funded by AHA, International Journal of Pharmaceutical Compounding; BHRT of progesterone was shown to relieve menopausal symptoms without compromising cardiac or vascular health.
2005 study in International Journal of Cancer; Progesterone actually decreases risk of breast cancer by 10%!
Several studies showing progesterone is cancer protective, anticarcinogenic properties
Studies validate progesterone has cardio-protective effect

22. PROGESTERONE…to the rescue
Stimulates osteoblast cells…bone formation cells that result in new bone growth
Using transdermal progesterone had
7-8% increase in bone density in first year
4-5% second year and
3-4% third year

23. PROGESTERONE…to the rescue
Resolves PMS symptoms in 83% women included in study
Tempers insulin release, normalizing blood sugar levels, thereby reducing food cravings
Increases sex drive
Improves quality of life: reduces sleep disorders, hot flashes, anxiety and symptoms of depression

24. BOOST ADRENAL SYSTEM Stress less, rest more Exercise
The Relaxation Response, Dr. Benson of Harvard Medical School
10-20 minutes daily, close eyes, breathe in deeply nose, say “one”, then breathe out, say “one”
Yoga

25. BOOST ADRENAL SYSTEM Eat to eliminate extra estrogen
Cruciferous veggies: broccoli, asparagus, cauliflower, spinach, celery, brussel sprouts, kale, cabbage, radish, turnip, collard and mustard greens
Citrus fruits (D-limonene): promotes detoxification of estrogen…and lowers weight
Insoluble fiber: (binds estrogen to it) whole grains, whole wheat breads, barley, couscous, brown rice, wheat bran, seeds, carrots, cucumbers, zucchini, celery, tomatoes
Lignans: ground flaxseed, sesame seeds, flaxseed oil
Eat organic

26. BOOST ADRENAL SYSTEM Supplements Go green B Vitamins Vitamin E
Calcium-Magnesium combo: ratio of 1,500 mg. Ca+ to750 mg. Mg+
DHEA
Go green
Avoid plastics, check labels, and buy pure soaps and toothpastes and other personal care products

27. WHAT YOU CAN DO
Progessence Cream (Natural Progesterone); rub ¼ tsp to body am and pm
Prenolone + Cream (Natural Pregnenolone, Progesterone & DHEA) apply same as above
Endogize; men 2 tab 3X daily, women 1 tab 3X daily
EndoFlex; dilute 1:1 and apply to lower back, thyroid, kidneys, liver, feet, glandular areas; diffuse 30 minutes 3X daily, may take as dietary supplement, dilute with V-6 and take up to 3X daily

28. WHAT YOU CAN DO UltraYoung Oral Spray; 3 sprays in mouth
Sulfurzyme and Super C taken together work synergistically to restore flexibility of vessels/cells
Thyroid specific: if after 3 months on Endogize, if temp. below 97.8 then take 2 Thyromin at bedtime (if taken in morning works on adrenals)

29. RESOURCES Newsletter: www.hormonewell.com
Newsletter:
Testing:
Salivary and Blood Spot Testing
ZRT Laboratory:

30. RESOURCES Life Extension® offers low cost blood test panels
To order a comprehensive Male or Female Blood Test Panel, call
Once you receive your blood test results, you can take them to your doctor or talk to a Life Extension Health Advisor at:

31. RECOMMENDED READING
Young, D. Gary. Pregnenolone, A Radical New Approach to Health Longevity, and Emotional Well-being.
Lee, John R. Natural Progesterone, The Multiple Role of a Remarkable Hormone
Lee, John R., with Virginia Hopkins. What Your Doctor May Not Tell You About Menopause.
Statements with claims have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat or prevent any disease.