1. Mapping Your Future: Careers in Biomanufacturing Winnell Newman Manager, Student Programs at BTEC Golden LEAF Biomanufacturing Training and Education Center NC State University winnell_newman@ncsu.edu (919) 515-0213 NC State University winnell_newman@ncsu.edu (919) 515-0213 winnell_newman@ncsu.edu www.btec.ncsu.edu

2. The Golden LEAF BTEC: The Promise and State of Delivery

3. NCBioImpact http://www.ncbioimpact.com/ Industry informed Training and Education Nearly 19,000 people work in biomanufacturing-related jobs in North Carolina. To train residents for these high-skill, high-paying jobs, the state has put together a comprehensive and unique training program to recruit, train and retain workers. The North Carolina Biotechnology Center has joined the North Carolina Biosciences Organization, the North Carolina Community College System, the University of North Carolina System to create and implement this program. The coordinated effort, called NCBioImpact Nearly 19,000 people work in biomanufacturing-related jobs in North Carolina. To train residents for these high-skill, high-paying jobs, the state has put together a comprehensive and unique training program to recruit, train and retain workers. The North Carolina Biotechnology Center has joined the North Carolina Biosciences Organization, the North Carolina Community College System, the University of North Carolina System to create and implement this program. The coordinated effort, called NCBioImpactNorth Carolina Biotechnology CenterNorth Carolina Biosciences OrganizationNorth Carolina Biotechnology CenterNorth Carolina Biosciences Organization

4. Consortium Partners Industry

5. Who Are We? Team – Professors and Staff Team – Professors and Staff 85,000 ft 2 Facility. “The Golden LEAF Biomanufacturing Training and Education Center - BTEC ” 85,000 ft 2 Facility. “The Golden LEAF Biomanufacturing Training and Education Center - BTEC ” Hands on Training Hands on Training By Government - For Industry By Government - For Industry Advisory Board comprised of Industry and Academic Partners Advisory Board comprised of Industry and Academic Partners Grow Biotech base in North Carolina Grow Biotech base in North Carolina First of a kind facility in USA First of a kind facility in USA

6. The Promise The Golden LEAF Biomanufacturing Training and Education Center (BTEC) on the Centennial Campus at North Carolina State University provides a unique pilot-scale, industry-informed, cGMP environment critical to developing a workforce proficient in the skills needed in the biomanufacturing industry. This educational investment will fuel prosperity by positioning North Carolina as a global leader in bioprocess education and biomanufacturing workforce development.

7. The Promise The Biomanufacturing Training and Education Center (BTEC) on the Centennial Campus at North Carolina State University provides a unique pilot-scale, industry-informed, cGMP environment critical to developing a workforce proficient in the skills needed in the biomanufacturing industry. This educational investment will fuel prosperity by positioning North Carolina as a global leader in bioprocess education and biomanufacturing workforce development. (2) Facility (1)Relevant (3)Curriculum (4)Student-Industry

8. Relevant: BTEC Organization Director Assoc. Director, Strategic Support Asst Director, Student Coord. Mgr, Student Programs Operations Managers Training Associates Asst. Director, F&A Purchasing (Richardson) Admin Support IT Sr. Instructional Designer Media Developer Assoc. Director, Academic Programs Faculty Lecturers PD & Analytical AD Executive Asst. Director Executive Assistant NCSU 16/38 = 42% Other Academia = 4/38 = 11% Industry = 18/38 = 47%

9. Relevant: BTEC Advisory Board Industry Biogen-Idec Biolex Cardinal Health Diosynth Eisai GSK KBI BioPharma Merck Novartis Novo-Nordisk Novozymes PhaseBio Talecris Biotherapeutics Wyeth NCCCS System Office BioNetwork NCBC Suppliers ABB Sartorius NCBIO/BMF Golden LEAF Foundation BRITE NCSU Provost VC, Finance & Business VC, Research & Grad Studies Dept Head, Genetics

10. (2)Facility

11. State-of-the Art Facility One-of-a-kind in USA right here at NCSU in Raleigh www.btec.ncsu.edu

12. What is Biotechnology? Technologies that use cells or biomolecules to solve problems and make useful products

13. 5 Largest challenges to Human Society – biotechnology involved in solving them So what good is Biotechnology?

14. A Typical Process Gene in cells grow a few cellsgrow a LOT of cells in bioreactor spin down and break open GFP – our teaching tool purify the product use special chemistry on beads filter / separate Green Fluorescent Protein which are packed in these housings materials (from Jellyfish)

15. cGMP – Examples of Jobs Staff Staff Education/Training Education/Training Structure Structure Process Process Validated Validated Cleaning Cleaning Testing Testing Release Release Facility Facility Design Design Flow Flow Cleaning Cleaning Changeover Changeover Validation Validation Pictures Courtesy Diosynth Biotechnology

16. Resources Web links with great information on: Education needed Job Titles / Pay ranges Biotech Guide Companies in North Carolina North Carolina Biotechnology Center www.ncbiotech.org http://www.ncbiotech.org/resource_center/jobs_in_nc/window_on_the_workplace/ http://www.ncbiotech.org/news_and_events/news_releases/guidebook.html http://ncbiotech.org/resource_center/biomanufacturing.html http://ncbiotech.org/ncbio/ncindustry/directories/companies/printable_company_list.html NCSU Office of Pre-College (efforts) http://www.fis.ncsu.edu/coop%5Fed/precollege/index.html Biomanufacturing It’s a growing industry in North Carolina … … which needs an educated-trained workforce

17. MORE …. Resources Web links to videos : See, hear, learn from real people in jobs in biotechnology http://aboutbioscience.org/ Videos - www.aboutbioscience.org/bc_title.htmlwww.aboutbioscience.org/bc_title.html http://www.ncabr.org/ The mission of the North Carolina Association for Biomedical Research is to promote public understanding and support for bioscience research. Biomanufacturing It’s a growing industry in North Carolina … … which needs an educated-trained workforce

18. Biotechnology is Booming Growth in Global Biotechnology, 2005-2006 Public company Data20062005Change Revenues (US $m) 73,478 64,21314.0% R&D expenses (US $m) 27,782 20,93433.0% Net Loss (US $m) 5,446 4,03935.0% Number of employees 190,500 173,11010.0% Number of companies Public 710 6735.0% Private 4,275 4,2630.3% US Biotechnology, 2005-2006 Industry Total20062005Change Revenues (US $m) 48 4213.4% R&D expenses (US $m) 27 2130.2% Net Loss (US $m) 6 458.5% Number of employees 180,800 170,5006.0% Number of companies Public 336 3315.0% Private 1,116 1,144-1.6% Source: Ernst & Young: “Beyond Borders: the Global Biotechnology Report 2007”

19. Recruit Support Place NCSU Students NCCCS Transfers Industry Professionals K-12 Industry- Ready Graduates Career Fairs Teacher Workshops Recruiting Trips Promotional Literature SCIBLS Tours One-on-one ISPE Student Chapter Student Projects Presentation Skills Internships Co-op/Internship Options Industry Information Job Fairs Resume Assistance Interview Practice Network Support Student Coordination Creating Value for Students and Industry

20. Assist HS students to make informed Choices K-12: 6-Initiatives Today Tomorrow – with your help

21. Plan Ask for Help Success Ask your Family Ask your Teachers Ask for Trips to companies Ask for Tours of companies Ask companies if they will support activities at your school Seek out Co-op / Internship Options Web search for Industry Information Learn about what Job Fairs are Practice writing your Resume Practice Interviews / discussions with people Build your Network Ask for Help Lots of people will help, if you are focused and ASK !