1.  1. I have West Nile Virus. I got the virus from a mosquito. Is this an example of a communicable or non-communicable disease and WHY?  2. Taking daily multi-vitamins to improve bone health is an example of (cause, symptom, treatment, or prevention)?  3. Describe why seeing blood in your urine is a sign of kidney disease/damage? 5/5 Daily Catalyst Pg. 67 Immune System

2.  Public health campaign presentations  Human body test on Thursday  See me for tutoring  Review day on Wednesday  Extra credit: gloves, paper towels, hand sanitizer, tissues, band aids, pens, pencils, paper, red pens, tape, glue, and colored paper, markers, and, white board markers  Extra credit school play  May 1, 2, 9  ½ sheet review STAPLED to your ticket  All make up work is due Monday, May 11th 5/5 Class Business Pg. 67 Immune System

3.  Grade danger list: Camila, Tashtoni, Estephanie, Lavone, joseph, Mohammad, Hannah L., and Chris Data Grade breakdownNumber of students A1 B11 C8 D3

4.  Daily Catalyst  Class Business  Objective  Presentations  Immune System notes  Practice time 5/5 Agenda Pg. 67 Immune System

5.  Present

6.  Today, we will compare the functions of the basic components of the human immune system and determine the relationship between vaccination and immunity. 5/5 Objective

7. Some diseases are communicable and can be transferred directly or indirectly from host to host. Other diseases are non-communicable. Which disease listed in the table is non-communicable?  A) shingles  B) impetigo  C) hemophilia  D) ringworm Lesson Starter

8.  It is Spring Break and you are at the coolest party in Kenner with all of your friends from BHS. As you enter the party you can feel the music vibrate through the floor and see flashing lights from the DJ. You grab a cup of Mountain Dew and hit the dance floor. Immune System Lab

9.  1. Count the number of healthy party goers  2. Count the number of sick party goers  3. Each student needs one cup of “mountain dew.” This cup is labeled and it is yours!  4. Do not drink the liquid in the cup! Immune System Lab

10.  The DJ (Mrs. Ireland) plays your favorite tune so you immediately head to the dance floor. On the dance floor, you friends have been dancing for hours and ask for a gulp of your Mountain Dew. Being the awesome friend you are, you pass your drink around to a few of your friends. When your cup gets back to you, there is only a little bit left. So you finish the cup and begin dancing. Immune System Lab

11.  5. You will exchange liquids with only 5 other party goers.  6. First, pour the contents of one cup into another cup, then pour half the contents back into the empty cup. This is one exchange  7. You may only exchange with 5 people  8. When you have exchanged with 5 people, return to your seat. Immune System Lab

12.  The next morning after the party you wake up at noon since you had an amazing time the night before. When you sit up, you notice your throat is sore and your head is throbbing. You try to call for your mom and no sounds comes out! Your throat is so sore and now your voice is gone! You have not been around anyone who is sick, How did this happen?! Immune System Lab

13.  Is your illness an example of a communicable or non- communicable disease?  Communicable  If the illness passed around at the party was bacterial, how would it be treated? If it was viral how would it be treated?  Antibiotics  No treatment, so rest Immune System Lab

14.  Turn and Talk with your classmates:  On Thursday, we talked about the fact that patients do not usually die of HIV/AIDS. They can die of something as small as a common cold. Explain why this is true.  HIV/AIDS (virus) attacks the immune system’s white blood cells and the body cannot fight off invaders, like the common cold. Immune System

15. This unit is about maintaining homeostasis in the human body! Homeostasis:

16. You want to be like this on the inside… Even if the outside world is like this…

17. One of the main ways to disturb homeostasis is disease! Did you know: Researchers from the Wright Patterson Medical Center in Dayton, Ohio, asked people standing in line at a grocery store checkout and at a high school concession stand to trade a $1 bill from their pocket for a new one. Then the doctors analyzed 68 of those old, worn bills. 87% of these bills contained harmful bacteria that could cause illness! Ewwwww

18. Essential questions: 1.What does my body do when a pathogen invades my body? 2.Why am I not always sick if I come in contact with pathogens often?

19.  Key Point #1: Function-  Fight off infection by keeping pathogens OUTSIDE the body and killing pathogens if they invade the body Function of the immune system: The army of the body!

20. Pathogens-review! 1. 2. 3. Pathogens cause disease! BACTERIA VIRUSES FUNGI

21. Key point #2: 1 st LINE OF DEFENSE Key Point #1: Fight off infection by keeping pathogens OUTSIDE the body 1.The skin 2.Mucous membranes 3.Stomach acid

22. WAIT!!! What if the pathogen gets past your first line of defense and breaks into your body???

23.  Key Point #3:  2 nd second line of defense  Inflammatory response  F________  S____________  R________  H________ Key Point #1: Fight off infection by keeping pathogens OUTSIDE the body and killing pathogens if they invade the body EVER WELLING EDNESS EAT

24. If the body’s first and second lines of defense don’t work then the immune system must identify and kill the pathogen.

25.  Key point #4:  3 rd line of defense  White blood cells  B Cells  T Cells  “Army”

26.  Key Point #5: Every pathogen has a unique fingerprint called an antigen. Pathogen

27. Step 1:  B-cells bring antibodies that bind to the antigen  Antibodies are flags Step 1- Investigate the problem Antibody binding to antigen

28.  Step 2:  Antibodies signal white blood cells to fight the pathogen Step 2- Call for back-up!

29. Step 3: T cells break down the pathogens and destroy them Step 3- Arrest the criminal!

30. Step 4- Put them in the system Step 4: Memory b-cells memorizes the pathogen Antibodies will be immediately released

31. Key Point #6:  Vaccines contain weakened or dead versions of the pathogens.  Your body releases antibodies in case it sees the pathogen again. Vaccines Vaccines DO get your body to produce the antibodies for the pathogen so if you do get sick, you can fight it off easily!

32.  Stop and Jot Propose an explanation for we see measles steadily decline after 1965.

33. 1. Which of the following is a part of your body’s first line of defense against pathogens? a.White blood cells b.Red blood cells c.Skin d.Nervous system For Class Points… C, the SKIN!!!

34.  2. A pathogen is… A) Pathway for white blood cells to follow to attack diseases B) A disease causing agent such as a virus or bacterial infection C) The best medicine for bacterial infections D) A cell that matches up to an antigen B, a disease causing agent!

35. 3. Which of the following is not part of your body’s immune system: a)Stomach b)White blood cells c)Skin d)antibodies A, stomach

36. 4. What part of your immune system can be compared to a SWAT team because it surrounds and destroys pathogens? a) Skin b) White blood cells c) antigens d) antibodies B, WHITE BLOOD CELLS

37. 5. Memory B-cells… a) Help your body remember the part of your body that was last infected b) Show your body how to fight all infections with the help of your brain c) Form after the pathogen has been fought off to help form antibodies in the future d) Remember the type of white blood cell that needs to be used to fight a certain disease C, form after a pathogen has been fought off

38. By the end of today you will be able to answer the questions: 1.Why am I not always sick if I come in contact with bacteria that often? 2.What does my body do when I do get sick?

39.  Directions: Using your notes, work with your partner to complete the immune system assignment. When you are finished, begin reviewing for the exit ticket and working on test corrections.  Time: 15 minutes  Noise: 1 (with partner) Work Time

40.  Name: __________ Period: 2 Date: 4/29 Score: _____/4  1. Who is the “army” of the immune system?  2. While you were building a real life model of DNA, you cut your arm. The cut on your arm starts to swell and turns red. What line of defense has been activated?  3. Why will the doctors check your white blood cell count if you are sick?  4. Describe how vaccines work. Exit ticket #15