1. MARKET SIZE 2012 | Onderstepoort Biological Products © |22nd February 2013Page 21 Estimated market size Estimated total market share ( OBP) Estimated vaccine market share (OBP) International Sales R2,5 billion5%13%+/-R45million =25% of sales (could be much more if OBP is GMP cerified)

2. | Onderstepoort Biological Products © |22nd February 2013Page 22

3. Competitor analysis | Onderstepoort Biological Products © |22nd February 2013Page 23 CompanyProduct range MSD ANIMAL HEALTH (Design Biologics)Complete PFIZER LABORATORIESComplete VIRBAC ANIMAL HEALTH80% BAYER ANIMAL HEALTH80% AFRIVET/ECO AH/COOPER VET PROD40% MERIAL90% CEVA ANIMAL HEALTH60% NOVARTIS70% ELANCO ANIMAL HEALTH40% OBP (PTY) LTD20% BOEHRINGER-INGELHEIM30% VTECH VETERINARY SOLUTIONS20% BIOTECH VETERINARY10% HIPRA10% IMMUNO-VET SERVICES CC10% STRIDE DISTRIBUTORS10% Deltaimmune 10%

4. OBP Product Portfolio  Rift Valley Fever – live, inactivated, Clone 13  African horse sickness  Bluetongue  B-Phemeral  Chlamysure  Lumpyskin  PI and IBR (in Leukopast 3) Fowl Pox ORF Equine Influenza | Onderstepoort Biological Products © |22nd February 2013Page 24 Actinomyces (Corynebacterium) pyogenes Anthrax Black Quarter Botulism Botulism/black quarter Blue Udder Brucella Rev 1 Brucella S19 Calf paratyphoid (live & inactivated) Corynebacterium Ovis E Coli Enterotoxaemia (pulpy kidney) Fowl Typhoid Gangrene Complex Haemophilus Coryza Lamb Dysentry Leukopast 3 (with IBR and PI) Leukopast Pasteurella Bovine Pasteurella Ovine Septicum Swelled Head Tetanus Vibrio (Campylobacter) Other Products Frozen infective blood against (in conjunction with OVI) Anaplasmosis Heartwater Redwater African / Babesiosis Redwater Asiatic / Babesiosis Antiserum Diagnostic Reagents (eg dourine, rose bengal) Bacterial Vaccine ProductsViral Vaccine Products

5. Company ranking | Onderstepoort Biological Products © |22nd February 2013Page 25 COMPANY YTD POS MSD ANIMAL HEALTH1 PFIZER LABORATORIES2 VIRBAC ANIMAL HEALTH3 BAYER ANIMAL HEALTH4 AFRIVET/ECO AH/COOPER VET PROD6 MERIAL5 CEVA ANIMAL HEALTH7 NOVARTIS8 ELANCO ANIMAL HEALTH9 OBP (PTY) LTD11 BOEHRINGER-INGELHEIM10 VTECH VETERINARY SOLUTIONS13 BIOTECH VETERINARY15 HIPRA12 IMMUNO-VET SERVICES CC14 STRIDE DISTRIBUTORS16

6. Market segments: end user market | Onderstepoort Biological Products © |22nd February 2013Page 26 Beef Cattle Dairy cattle (700) sheepFeedlot Combination products Cost effective Input is a problem No Brand loyalty Can wait on back order Combination products Cost effective Input is a problem Brand loyalty Will not wait on back order Combination products Cost effective Input very serious problem Can wait on back order Combination products Cost effective Input very serious problem Brand loyalty Will never wait 35 000 (farmers) 1,5 mil/yr

7. | Onderstepoort Biological Products © |22nd February 2013Page 27 Coops Vets Wholesalers Gov- ? Distribution segment Farmer 40% 20% 30% 3-5%

8. Product mix per segment | Onderstepoort Biological Products © |22nd February 2013Page 28 Beef Cattle Dairy cattle (700) Sheep/GoatsFeedlot Anth/BQ/BOT Cl. Noyv LSD, RVF S19 Gasgangrene, calf paratyphoid Pasteurella Anth/BQ/BOT Cl. Noyv LSD, RVF S19 Gasgangrene, calf paratyphoid Pasteurella Leucopast & L3 B phemeral Anth/BOT Cl. Noyv RVF BT Past PK Anth/BQ/BOT Cl. Noyv LSD, RVF Gasgangrene, Calf paratyphoid Pasteurella Leucopast & L3

9. OBP -Product life cycle | Onderstepoort Biological Products © |22nd February 2013Page 29 Mature phase Declining phase Growth Phase 80% of bacterial products LSD, AHS, Bl vaccines BT, B. PHEMERAL, RVF Chlamysure; Turbeculine; Past bov/ovine Time GrowthGrowth

10. Sales performance forecast in 3-4 yrs | Onderstepoort Biological Products © |22nd February 2013Page 30