1. Оксигенатор Витал (Vital) и его конкуренты
Barbara Sleypen
Product Manager Infusion & perfusion Systems

2. Oxygenator Vital® Перенос кислорода

3. Oxygenator Vital® Транспорт СО2

4. Oxygenator Vital® Эффективность транспорта

5. Oxygenator Vital®

6. Oxygenator Vital® Показатель теплообмена

7. Vital (variable chamber)
HEAT EXCHANGER LOCATION COMPARISON- теплообмен в системе оксигенатор и резервуар
Other oxygenator
(Full chamber)
In the oxygenator
Part of the priming volume.
The heat exchanger efficiency is compromised by the priming volume
Heat exchanger is in the venous line
Vital (variable chamber)
In the venous reservoir
Not part of the priming volume
Not compromised by priming volume.
Heat exchanger is in the venous line

8. ADULT OXYGENATOR FEATURE Характеристики взрослого оксигенатора в сравнении
TEST CONDITIONS: Bovine 11,5 Hgb 64% 37°C (A.A.M.I) Blood Flow: 7 l/ min Water Flow: 15 l/ min

9. P (mmHg) X Index of Hemolysis Показатель гемолиза форменных элементов

10. Nipro Vital® в сравнении (Medtronic)
Features
O2 transfer (ml/min)
CO2 transfer (ml/min)
Surface area (m²)
Visible blood path
Priming Volume (ml)
Heat exchanger efficiency
Arterial temp port
Venous sample port
Venous temp port
Venous reservoir vol (ml)
Recirculation line
Vital
420
350
1.9
Yes
180
0.61
4000
yes
Affinity NT
435
2.5
270
0.55 No
Maxima
375
250
2.0
450
0.44
3800 no

11. Medtronic Affinity NT

12. Medronic Affinity NT
Efficient gas transfer due to patented radial flow design. The graduated bundle density design of the oxygenator maximizes gas transfer while blood shear, priming volume and blood side pressure drop are minimized.

13. Nipro Vital® в сравнении (Maquet)
Features
O2 transfer (ml/min)
CO2 transfer (ml/min)
Surface area (m²)
Visible blood path
Priming Volume (ml)
Heat exchanger efficiency
Arterial temp port
Venous sample port
Venous temp port
Venous reservoir vol (ml)
Recirculation line
Vital
420
350
1.9
Yes
180
0.61
4000
yes
Polystan
450
300
2.0
Partiel
280
0.71 No
4200
Jostra Quadrox
315
1.8
250
0.62
Jostra Quadrox D

14. Maquet Jostra Quadrox Open system
Set-up flexibility on the heart-lung machine: Quadrox can be used with a pre-mounted venous hardshell cardiotomy reservoir or as a stand-alone unit with a separate hardshell reservoir.
Closed System
Combine the Quadrox with a venous softshell reservoir and a cardiotomy reservoir in a closed system. With the Quadrox’s blood inlet and outlet in line, there is a sgnificant reduction in tubing lenghts, and consequently in priming volume: a customized set-up to the patient.
Individual ways to enhanced biocompatibility
For optimum blood handling the Quadrox is available with either Safeline or Bioline Coating. Their standard Safeline Coating minimizes trans-membrane pressure gradient and guarantees an exceptional relability. Bioline coating ensures a homogeneous, highly biocompatible surface which effectively protects patient’s blood.

15. Maquet Jostra Quadrox D
Superior fibre technology
The Quadrox D with diffusion membrane: Quadrox D provides constant, optimum safety especially in the case of prolonged perfusion. Its tight and hydrophobic hollow-fibre membrane made of polymethylpentene avoids plasma leaks. It effectively prevens the formation of micro-bubbles and protects against bacterial contamination from the gas side. Quadrox D features the outstanding handling characteristics and performance data of the Quadrox oxygenator with the microporous membrane.
Individual ways to enhanced biocompatibility
For optimum blood handling the Quadrox is available with either Safeline or Bioline Coating. Their standard Safeline Coating minimizes trans-membrane pressure gradient and guarantees an exceptional relability while significantly reducing blood trauma. Bioline ensures a homogeneous, highly biocompatible surface which effectively protects blood. Its outstanding performance is ideal for prolonged perfusion.

16. Maquet Polystan High performance
Oxygenator performance is a question of balanced parameters. The SAFE MAXI oxygenator provides a very effective air and bubble trapping and has one of the highest oxygen transfer rates available with moer than adequate excess reserve capacity. Likewise the heat exchanger is one of teh most efficient to ensure efficient cooling and rewarming.
Full rotation
The complete arterial outlet section of the SAFE MAXI oxygenator is fully rotatable through 360 degrees as is the entire oxygenator at the reservoir coupling.
This both optimises and greatly simplifies positioning of the oxygenator in relation to pump patient and reservoir. It also facilitates both left and right-hand pump set-ups and to shortening of blood lines with better access and visibility.
These features combined with the also fully rotatable venous inlet of the venous inlet of the venous reservoir give the SAFE MAXI oxygenator and VHK reservoir optimum positioning flexibility.
Standard coating
All SAFE MAXI oxygenators are surface treated with Jostra SAFELINE® coating to reduce tension on the blood contact surfaces and to significantly reduce oxygenator drops during extracorporeal circulation. Safeline improves blood compatibility and thrombocyte adhesion
New venous cardiotomy reservoir
With a minimum operating volume and a maximum capacity of 4200 ml the VHK reservoir exceeds the requirements for safe and effective management of venous return and suction blood. Clear, precise and easily eradable volume scales make volume management and monitoring accurate and reliable.
Fully transparent housings
The clear, high impact polycarbonate housings ensure full visibility. This provide security the perfusionist and contributes to patient safety.

17. Nipro Vital® в сравнении (Sorin)
Features
O2 transfer (ml/min)
CO2 transfer (ml/min)
Surface area (m²)
Visible blood path
Priming Volume (ml)
Heat exchanger efficiency
Arterial temp port
Venous sample port
Venous temp port
Venous reservoir vol (ml)
Recirculation line
Vital
420
350
1.9
Yes
180
0.61
4000
yes
Monolyth
400
310
2.2
285
0.55 No
3500
Monolyth Pro
4600
Synthesis
290
2.0
430
0.62
4300
PrimeO2X
460
340
250

18. Sorin - Synthesis
Integrated arterial filter and staged cardiotomy filter that adjusts to meet flow requirements
In the cardiotomy filter:
1 screen filter
2 depth filters
Heat exchanger uses a fan folded, stainless steel design
Arterial filter plays an essential role in cerebral protection and decreases the risk of systemic embolization. The unique linear filter can be easily primed and offers better visibility

19. Sorin – PrimO2X Superior, effecient gas transfer
It delivers one of the highest gas exchanges available for the exposed surface area
Low priming volume
Advance reservoir design
A hybrid screen/depth cardiotomy filter reduces holdup volume compared to depth media filters
Reliable Oxygenator membrane
Intuitive, fast ans easy set-up
Easy port recognition, an integral recirculation line and a unique cardioplegia port provide an easier set-up in emergency situations.
High Biocompatibility
Reservoir and oxygenator design may reduce the total foreign surface area in contact with blood. Phosphorylcholine treatment provides a stable coating, which is demonstrated to be effective in improving platelet preservation and reducing platelet foreign surface adhesion.

20. Nipro Vital® compared to (Cobe)
Features
O2 transfer (ml/min)
CO2 transfer (ml/min)
Surface area (m²)
Visible blood path
Priming Volume (ml)
Heat exchanger efficiency
Arterial temp port
Venous sample port
Venous temp port
Venous reservoir vol (ml)
Recirculation line
Vital
420
350
1.9
Yes
180
0.61
4000
yes
Optima
390
1.7
Partial
260
0.6 No no
Duo
400
2.6
0.7
Apex
450
410
2.0
310

21. Cobe – Apex™ Advanced flow design provides improved O2 transfer
Integral purge and recirculation line simplifies priming and tubing pack design
Unique cardioplegia port provides access to arterial blood without cutting into tubing
Highest gas transfer available from Cobe CV
Venous inlet, lid, reservoir and oxygenator rotates independently
Same temperature probe and bracket as Optima XP and Duo

22. Cobe – Optima XP
High gas transfer reserves capacity for extra O2 when needed
Efficient hollow fiber, cross wound mat technology for consistent performance
Top to bottom membrane flow for enhanced air handling
Bottom to top heat exchanger flow for ease of priming
High performance/high integrity heat exchanger
Ultra-low priming volume

23. Cobe - Duo® Flat sheet membrane for enhanced air handling
Continuous bloodside netting improves gas exchange
Top to bottom membrane flow for enhanced air handling
Bottom to top heat exchanger flow for ease priming
High performance/high integrity heat exchanger

24. Nipro Vital® compared to (Dideco)
Features
O2 transfer (ml/min)
CO2 transfer (ml/min)
Surface area (m²)
Visible blood path
Priming Volume (ml)
Heat exchanger efficiency
Arterial temp port
Venous sample port
Venous temp port
Venous reservoir vol (ml)
Recirculation line
Vital
420
350
1.9
Yes
180
0.61
4000
yes
903
Avant
435
340
1.7
Partiel
250
0.68 No
3500
703 Compactflo
400
2.0
270
4500
Compactflo EVO
460
4300

25. Dideco – 903 Avant Isolated chamber for cardiotomy sequestration
Bottom entry venous reservoir for safety and performance
Connection valve to direct suction blood where it’s needed
High performance gas transfer
Unique cardioplegia access port
Dual flow rate purge/recirculation valve
4700 ml total reservoir capacity
2.0 m² membrane surface area
8 LPM maximum flow

26. Dideco – 703 Compactflo

27. Dideco – Compactflo EVO

28. Nipro Vital® compared to (Terumo)
Features
O2 transfer (ml/min)
CO2 transfer (ml/min)
Surface area (m²)
Visible blood path
Priming Volume (ml)
Heat exchanger efficiency
Arterial temp port
Venous sample port
Venous temp port
Venous reservoir vol (ml)
Recirculation line
Vital
420
350
1.9
Yes
180
0.61
4000
yes
Capiox SX 18
400
260
1.8
270
0.68 No no
Capiox SX 25
490
310
2.5
340
Capiox RX 15
330
230
1.5
205
0.53
Capiox RX 25
360
250

29. Terumo – Capiox® SX Exclusive hollow fiber Low priming volume
Large reservoir capacity
Consistent, easy-to-use design
Detachable reservoir for increased versatility: the hardshell reservoir can be used attached to the oxygenator module, or detached and mounted separately as required.
Choice between open and closed system: these oxygenator systems can also be used with a soft venous reservoir in a closed system configuration.

30. Terumo - Capiox® RX High flow with very low priming volume
Optimized air handling
Exclusive hollow fiber, woven
Flexible for every setup

31. Nipro Vital® compared to (Medos)
Features
O2 transfer (ml/min)
CO2 transfer (ml/min)
Surface area (m²)
Visible blood path
Priming Volume (ml)
Heat exchanger efficiency
Arterial temp port
Venous sample port
Venous temp port
Venous reservoir vol (ml)
Recirculation line
Vital
420
350
1.9
Yes
180
0.61
4000
yes
HiLite7000
490
360
Partial
275
0.5 No no
HiLite 7000 LT

32. Medos – HiLite 7000
High performance device, designed for a safe and reliable gas transfer with high heat exchange performance. Hollow fiber is achieved by the vertical blood-, water- and gasflow directions. Due this configuration and the transparency of the housing, the observation of air and the deaering-procedure are very simple and safe.