1. Continuing Medical Education Programs Dr. Anika Niambi Al-Shura, Lecturer Copyright 2014 Niambi Wellness. All rights reserved

2. Health Communications in TCM Cardiology Integrative Anatomy and Patho-physiology in TCM Cardiology Integrative Examination in Cardiovascular Disease Integrative Diagnosing of Cardiovascular Diseases Integrative Study of Hematology in Cardiology Integrative Hyperlipidemia Treatments in Cardiovascular Disease Integrative Cardiovascular Clinical Therapies Copyright 2014 Niambi Wellness. All rights reserved Level 1 Course Titles

3. Niambi Wellness continuing medical education programs presents Copyright 2014 Niambi Wellness. All rights reserved

4. Integrative Hyperlipidemia Treatments in Cardiovascular Disease Copyright 2014 Niambi Wellness. All rights reserved

5. This course is approved by the following agencies: National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM) for 5 PDA points and Florida State Board of Acupuncture for 5 CEUs. The companion textbook: Essential Treatments in Cardiovascular Chinese Medicine I: Hyperlipidemia must be ordered at www.elsevier.com Copyright 2014 Niambi Wellness. All rights reserved

7. This course covers the basic Western medicine and Traditional Chinese Medicine sciences of blood lipids, clinical significance, differentiations, diagnoses, treatment principles and methods. Copyright 2014 Niambi Wellness. All rights reserved Course Description

8. Course Objectives -Describe the basic etiology of lipoprotein disorders, including genetic disorders -Describe the clinical presentations of lipoprotein disorders as a sign of cardiovascular diseases -Describe Western medicine and Traditional Chinese medicine prescriptions for lipoprotein disorders. -Describe the suggested medicated diet for patients on a treatment course. Copyright 2014 Niambi Wellness. All rights reserved

10. Course Modules Copyright 2014 Niambi Wellness. All rights reserved

11. Module 1: Etiology Module 2: Clinical Presentations Copyright 2014 Niambi Wellness. All rights reserved

13. Module 1 Etiololgy Copyright 2014 Niambi Wellness. All rights reserved

14. Chapter 1: Etiology of Lipoprotein Disorders in Chinese Medicine and Western Medicine Contents Copyright 2014 Niambi Wellness. All rights reserved

16. Chapter 1: Etiology Copyright 2014 Niambi Wellness. All rights reserved

17. Part 1: Integrative Perspectives Part 2: Genetics Part 3: Answers to Textbook Questions Contents Copyright 2014 Niambi Wellness. All rights reserved

19. Part 1: Integrative Perspectives Copyright 2014 Niambi Wellness. All rights reserved

20. Western Medicine Copyright 2014 Niambi Wellness. All rights reserved

21. The lipid transport system moves lipids from the hepato-biliary and gastrointestinal system to areas of the body where it is needed to produce certain hormones. Copyright 2014 Niambi Wellness. All rights reserved

22. Cholesterol (VLDL) is sent from the liver into the small intestine for chylomicron processing. Copyright 2014 Niambi Wellness. All rights reserved

23. Patients with chronic renal failure often have elevated triglyceride levels with a low HDL. Copyright 2014 Niambi Wellness. All rights reserved

24. Chinese Medicine Copyright 2014 Niambi Wellness. All rights reserved

25. Tan zhuo Tan zhuo is considered turbid phlegm. Copyright 2014 Niambi Wellness. All rights reserved

26. It is the thick, sticky and stubborn substance that clogs orifices, the lungs and vessels. Copyright 2014 Niambi Wellness. All rights reserved

27. It can also be considered the transformed turbid fluids. Copyright 2014 Niambi Wellness. All rights reserved

28. These fluids can be found in the tissues between the skin and muscle which give the heavier body appearance. Copyright 2014 Niambi Wellness. All rights reserved

29. Xue Yu Xue yu is considered as blood stasis which includes clotting, hemorrhage, spotting and pain. Copyright 2014 Niambi Wellness. All rights reserved

30. Xuan yun Xuan yun is also considered as dizziness or vertigo. Copyright 2014 Niambi Wellness. All rights reserved

31. It is seen especially with circumstances related to sticky phlegm obstruction, blood deficiency and qi deficiency. Copyright 2014 Niambi Wellness. All rights reserved

33. Part 2:Genetics Copyright 2014 Niambi Wellness. All rights reserved

34. Familial Hyperlipidemia (FH) Copyright 2014 Niambi Wellness. All rights reserved

35. Type I Type I is hyperlipidemia It is marked by increased transport of cholesterol on the chylomicrons produced in the small intestine and pancreatitis. Copyright 2014 Niambi Wellness. All rights reserved

36. Type II Type II is hypercholesterolemia It is marked by defects in LDL receptors which control inter and extra- cellular reception of cholesterol. Copyright 2014 Niambi Wellness. All rights reserved

37. Some patients may develop type II diabetes, hypothyroidism, atherosclerosis and coronary artery disease. Copyright 2014 Niambi Wellness. All rights reserved

38. Type III Type I is hyperlipoproteinemia It is marked by a mutation of the ApoE gene and increased production of LDL leading to facial and palmar xanthomas. Copyright 2014 Niambi Wellness. All rights reserved

39. Type IV Type IV is hyperlipoproteinemia. It is marked by stable cholesterol levels while triglycerides including LDL are elevated. Copyright 2014 Niambi Wellness. All rights reserved

40. Type V Type V is hyperlipoproteinemia. It is a combination of type I and IV. Copyright 2014 Niambi Wellness. All rights reserved

42. Apolipoprotein B Copyright 2014 Niambi Wellness. All rights reserved

43. APO B 100 This gene is found in high cholesterol levels associated with macrophage response to a Staphlococcus aureus infection. Copyright 2014 Niambi Wellness. All rights reserved

44. Macrophage foam cells leave cholesterol streaks in the arteries and cause endothelial damage. Copyright 2014 Niambi Wellness. All rights reserved

45. Apo B48 and APO E These genes are found in chylomicrons which transport lipoproteins from the small intestines to the body through the blood flow. Copyright 2014 Niambi Wellness. All rights reserved

46. Elevated presence of APO B raises LDL levels and complicates Diabetes Mellitus treatment. Copyright 2014 Niambi Wellness. All rights reserved

47. Apolipoprotein (APO)E E2: increased in risk of coronary artery disease and Parkinson disease Copyright 2014 Niambi Wellness. All rights reserved

48. Apolipoprotein (APO)E E3: studied with E4 for clinical significances E4: increased risk of atherosclerosis, sleep apnea, ischemic cerebrovascular disease, multiple sclerosis, alzheimers disease. Copyright 2014 Niambi Wellness. All rights reserved

50. Part 3: Textbook Answers Copyright 2014 Niambi Wellness. All rights reserved

51. #1 Genetic, diet and lifestyle cause lipoprotein disorders. #2 The product is sent back to the liver for fat metabolising. Copyright 2014 Niambi Wellness. All rights reserved Answer block

52. #3 Patients with glomerular nephritis #4 a. renal disease b. hepatic disease c. cardiovascular disease Copyright 2014 Niambi Wellness. All rights reserved Answer block

53. #5 Staphylococcus aureus contributes to elevated LDL levels by leaving cholesterol streaks. #6 Elevated LDL levels contribute to coronary artery disease. #7 Elevated fat levels lead to complications in other diseases. Copyright 2014 Niambi Wellness. All rights reserved

55. Module 1 Review Questions

56. Complete the Module 1 review interactive practice quiz. Copyright 2014 Niambi Wellness. All rights reserved

57. Please continue on to Module 2 Copyright 2014 Niambi Wellness. All rights reserved