1. BREAST CANCER OVERVIEW Polly Stephens, M.D.

2. BREAST ANATOMY

3. breastcancer.org

4. Ductal Carcinoma In Situ

5. Calcifications

6. CALCIFICATIONS

7. The

8. Invasive Ductal Carcinoma

10. Breast cancer

12. Vascular/Lymphatic Invasion

13. Bone scan

14. Liver metastases

15. MAMMOGRAPHY In America, most breast cancers are diagnosed on mammogram 1 st mammogram age 35 –Or 10 years before your mother was diagnosed with breast cancer Yearly starting age 40 About 10% of cancers are not seen on mammogram. DO YOUR OWN EXAM

16. St Francis Cancer Institute

17. BIOPSY Ultrasound-guided Stereotactic MRI guided biopsy

18. STEREOTACTIC BIOPSY

19. ULTRASOUND BIOPSY

20. INVASIVE DUCTAL CARCINOMA Overall survival 75% Stage –0Ductal carcinoma in situ –Itumor <2cm, no lymph nodes –IItumor 2-5cm, <4 lymph nodes –IIItumor >5cm, >4 lymph nodes –IVdistant metastases

21. INFLAMMATORY BREAST CANCER P’eau d’orange

23. Treatment Local control –Lumpectomy/mastectomy –Radiation Distal control –Chemotherapy

24. Sentinel node biopsy

25. Mammosite

26. External Beam Radiation

27. Who needs chemotherapy? If there is a risk of cells in the blood stream looking for a place to settle –Bone, Liver, Lung, Brain There is no blood test for breast cancer cells in the blood stream

28. Genetics BRCA 1 and 2 –Alterations or mutations in these genes increase ones risk for breast and ovarian cancer –Only about 5% of breast cancer patients are BRCA +